Protein Alignment emb and Ranbp21

DIOPT Version :10

• Sequence 1: NP_723391.2
• Gene: emb / 34167
• FlyBaseID: FBgn0020497
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: NP_608339.2
• Gene: Ranbp21 / 32970
• FlyBaseID: FBgn0031051
• Length: 1241
• Species: Drosophila melanogaster
• Alignment Length: 1185
• Identity: 219/1185 - (18%)
• Similarity: 394/1185 - (33%)
• Gaps: 348/1185 - (29%)

  Fly    17 SQKLDINLLDKIVEVVYTAQGEQLRL-AQSILTTLKEHPEAWTRVDSILEYS--QNQRTKFYALQ 78
            ::.|...|...|..|:.....:|.|| |.......||......:|...|..|  .||:.:.:.||
  Fly     7 TEALAAELASAIDLVMNPMTQQQARLEAYMACERFKEESPMCAQVGLFLASSPQSNQQVRHFGLQ 71

  Fly    79 ILEEVIKTRWKVLPRNQCEGIKKYVVSLIIKTSSDPIVMEQNKVYL---NKLNMILVHILKREWP 140
            ::|..||.||..:...:    |.|:....||..:..:...:::..|   :.|:.|:|.::|||||
  Fly    72 LIEYTIKYRWNCITHEE----KVYIKDNAIKMLNVGVGPAEDRSLLPTKDALSRIIVEMIKREWP 132

  Fly   141 RNWETFISDIVGASKTNESLCMNNMVILKNLSEEVFDFSQGQITQT-----KAKHLKDTMCSEFS 200
            :.|...:.::..|....|:.....:::...|.|:|      .:.||     :.|.:...:.:..:
  Fly   133 QQWSDLLPELSQACTKGEAQTELVLLVFLRLVEDV------ALLQTIESNQRRKDMYQALNNNMN 191

  Fly   201 QIF------------------TLCSFVLENSMNAALIHVTLETLLRFLNWIPLGYIFETQ-QIET 246
            .||                  .||::...|: ::.::.:.|.||..|:.|:.:.:|..:. ::..
  Fly   192 DIFEFFLRLVEQHVTAFRETTRLCNYTKANA-HSRVVEMVLLTLSGFVEWVSIQHIMSSNGKLMH 255

  Fly   247 LIFKFLSVPMFRNVTLKCLSEIAGLTAANYDEN-FATLFKDT----MVQLEQIVGQNMNMNHVFK 306
            .:...|:...|:....:||::|........:.. ...||.:.    :.|..||
  Fly   256 FLCILLNDKAFQCNAAECLAQITNRKGQTKERKPLLQLFNEEPLRYIYQASQI------------ 308

  Fly   307 HGSDTEQELVLNLAMFLCTFLKEHGKLVEDAKYVDYLNQALMYLVMISEVED-------VEVFKI 364
             .:||...|.:...:   .|||         |.:..||.....||.:...:|       :||...
  Fly   309 -PADTSSTLAVEQHL---NFLK---------KLLQVLNGMAQQLVALWGKDDATQRPVHLEVLLE 360

  Fly   365 CL----------------EYWNSLVEDLYNSEFFH-----PTLESTKRQQV----YPRRRFYAPI 404
            ||                ..|..|::...:|:.|.     |.|..|...::    ||........
  Fly   361 CLLLLVQHPSLGLSHGSALIWQLLLKHEPSSKDFAMVNYIPKLIHTIAPRIVKLPYPASASSPAS 425

  Fly   405 LSKVRFIMISRMAKPEEVLVVENENGEVVREFMKDTNSINLYK--NMRETLVFLTHLDSVDTDRI 467
            ||...:|.:...::.|..|..          |...|:.:.:::  .:.:.||...:     .::.
  Fly   426 LSTEAYIRLEHDSEEEYALYF----------FRCRTDFLEIFRLATLVQPLVTYGY-----CEQW 475

  Fly   468 MTLKLLNQVNGSEFSWKNLNTLCWAIGSISGAFCEEDEKRFLVTVIKDLLGLCEQKKGKDNKAII 532
            :..:|.|....::...|:.|..|..:..:   :.|.|.   ||:|:..:|
  Fly   476 LQQRLRNAQIEADAEVKSGNVSCSVLDPV---YLEWDA---LVSVLDGVL--------------- 519

  Fly   533 ASNIMYVVGQ--YPRFLRAHWKFLK-TVVNKLFEFMHETHDGVQDMACDTFIKIAIKCRRYFVTI 594
             |.|:.|..:  .|..||...:.|| ..:|.|                 |: .|.:.|.......
  Fly   520 -SRILLVAERPSVPAGLRLLEECLKLETINPL-----------------TY-SILLSCISALFVF 565

  Fly   595 QPNEACTFIDEILTTMSSIICDLQPQQVHTFYEAVGYMISAQVDQVQQDVLIERYMQLPNQVWDD 659
            ....||.........||.:  .|.|:.:...:.|:                   .|:.||:: :.
  Fly   566 LSMSACQITATNCVAMSGV--SLLPRVLDKIFRAL-------------------VMKPPNEL-EK 608

  Fly   660 IISRASKNVDFLKNMTAVKQLGSILKTNVAACKALGHAYVIQLGRIYLDMLNVYKITSENIIQAI 724
            :.::::||:.        :...|:|       ..|.|.|.:.|..::           |.|...:
  Fly   609 VQAKSAKNLR--------RHAASLL-------VKLAHKYPLLLLPVF-----------EQINGHV 647

  Fly   725 EVNGVNVNNQPLIKTMHVVKKETLNLIS----------------------EWVSRSNDNQLVMD- 766
            |:.........|.:.|....:|.|.|||                      ||::..:..:..:|
  Fly   648 ELLLKEPGKHQLCRLMRTTLQEALILISNHFCDFERQTLFIEHIVQDKRTEWLAFGDALKSPLDF 712

  Fly   767 -NFI----PP---------------LLDA---ILLDYQRCKVPS--------------------- 787
             :|:    ||               ||||   :|...:||..|.
  Fly   713 MSFVGLDKPPIFAVEGAVTLQNRSRLLDALHVVLGVVKRCTWPDDPERAQRGGFVIGCTELGNPI 777

  Fly   788 AREPKVLSAMAIIVHKLR-QHITNEV--PKIFDAVFE-------------------CTL--DMIN 828
            .|.|.....:.::.|.|. ..:.||:  |:...|:.|                   |.|  |.::
  Fly   778 CRNPATKHIVPLLSHVLSLMRVLNELFAPEALQALSEGYRGIHGMMEHEKKLLMGICALPTDPLD 842

  Fly   829 KNFEDFPQHRLSFYELLQAVNAHCFKAFLNIPPA------QFKLVFDSVVWAFKHTMRNVADMGL 887
            ......|.........:..|...|:....:..|:      |...:.|::|......|..|.|..|
  Fly   843 TTIRSEPTAFEKMQTFMMMVTEGCYHLMGSAGPSLGRDLYQLMGLSDAIVTNVFSRMDLVPDYRL 907

  Fly   888 ----NILFKMLQNLDQHPGAAQSFYQTYFTDILMQIFSVVTDTSHTAGLPNHAII--LAYMFSLV 946
                .:.||..         ..|...:::..:|:.:|      :|.|.|....:.  ..|:.||.
  Fly   908 RPIIRVFFKPF---------VYSCPPSFYDSVLVPLF------AHLAPLMCERLTRRWIYIASLY 957

  Fly   947 ENRKITVNLGPIPD---------NMIFIQEYVASLLKSAFTHLSDNQVKV-FVTGLFNLDENVQA 1001
            |:.::.   |.:.|         |....:||: .:||.|   |...|:.. .|....|.:.|..|
  Fly   958 ESGQLD---GEVNDTQEVLEDQLNRTLTREYL-DVLKIA---LVGGQIGADHVAAGANANSNSVA 1015

  Fly  1002 F--KEHLRDFLIQIR 1014
            .  :||..|...|.|
  Fly  1016 MENEEHSMDSAPQSR 1030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
emb	NP_723391.2	CRM1	13..1023	CDD:227432	219/1185 (18%)
Ranbp21	NP_608339.2	IBN_N	34..101	CDD:397745	19/70 (27%)
		Xpo1	116..274	CDD:462459	30/164 (18%)
		Exportin-5	319..1196	CDD:437105	151/849 (18%)