Protein Alignment emb and xpo5.2

DIOPT Version :9

• Sequence 1: NP_001303316.1
• Gene: emb / 34167
• FlyBaseID: FBgn0020497
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: XP_031757698.1
• Gene: xpo5.2 / 100487222
• XenbaseID: XB-GENE-996403
• Length: 1190
• Species: Xenopus tropicalis
• Alignment Length: 1113
• Identity: 202/1113 - (18%)
• Similarity: 362/1113 - (32%)
• Gaps: 384/1113 - (34%)

  Fly    67 SQNQRTKFYALQILEEVIKTRWKVLPRNQCEGIKKYVVSLIIKTSSDPIVMEQNKVYLNKLNMIL 131
            |.:...:.:.|.:||.|||.||.|:|......:|..:: |:|.....||:.|:..: .:.:..::
 Frog    63 SHSPCVRHFGLHVLEHVIKFRWNVMPLGDRVFVKNRMM-LLISYGIHPILEEKGHI-KDVIARVV 125

  Fly   132 VHILKREWPRNWETFISDIVGASKTNESLCMNNMVILKNLSEEVFDFSQGQITQTKAKHLKDTMC 196
            |.|:|||||.||...::::...:...::.....|.||..|:|::..|....|...|..|  .::.
 Frog   126 VEIIKREWPWNWLGMVNELAFTANFGDAQMELVMFILLRLAEDLGPFETRPIWCLKELH--KSLG 188

  Fly   197 SEFSQIFTLCSFVL----ENSMNAA-----LIHVTLETLLRFLNWIPLGYIF-ETQQIETLIFKF 251
            :...:|:.....||    :|..|..     :....|.||..::..:|...|. :...:..|:...
 Frog   189 ANMGKIYDFILIVLQRCEQNHQNLTQGQFRVAAAALRTLAGYIKCLPTRLIMADNCTLLWLLCVL 253

  Fly   252 LSVPMFRNVTLKCLSEIAGLTAAN-----YDEN--FATLFKD-------TMVQLEQIVGQNMNMN 302
            |:||..:....:||     |.|.|     .:|.  ...||::       |..||..
 Frog   254 LNVPELQMEAAECL-----LLAVNKKGLLLEERVPLLILFREDALRYILTAAQLAD--------- 304

  Fly   303 HVFKHGSDTEQELVLNLAMFLCTFLKEHGKLVEDAKYVDYLNQALMYLVMIS--EVEDVEVFKIC 365
                  ||..||  .|..:     ||..|:::.|      |...|..|..::  ||:..|.|...
 Frog   305 ------SDPLQE--RNYVI-----LKMIGQILCD------LGNQLCALTQVTAFEVKTPETFDRY 350

  Fly   366 LEYWNSLVEDLYNSEFFHPTLESTKRQQVY-------------PRRRFYAPILSKVRFIMISRMA 417
            ||...||..        ||:|..|....|.             |:.....|.:.:...:.|.::.
 Frog   351 LEALLSLTR--------HPSLFLTSSAFVIWGTLFSHRVLSHDPQLTAAIPDVLRAAMVSIVKVG 407

  Fly   418 KPEEVLVVENE-NGEVVR-EFMKDTNSINLYKNMRETL-VFLTHLDSVDTDRI-------MTLKL 472
            .|.    ::|. :.|..| :|..||.....:.:.|:.: :.:..|..:||..:       |..:|
 Frog   408 YPS----MDNSPSCEYSRLDFDDDTEFNTFFLSFRKQMGIVVRSLCRLDTRTVLHVATEWMRHQL 468

  Fly   473 LNQVNGSEFSWKNLNTLC---------WAIGSISGAFCEEDEKRFLVTVIKDLLGLCEQKKGKDN 528
            ...::....:..::..||         |...|.   ||.|           ....||.....::
 Frog   469 SAPLDPGPHNATSVEALCSPHSPSFLHWEAMSF---FCSE-----------VFAQLCRPLSAEE- 518

  Fly   529 KAIIASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAIKCRRYFVT 593
                            ..||...:.|:.|::      :||.|           .:.:.|
 Frog   519 ----------------ALLREGVRLLQRVIS------YETKD-----------PLIVSC------ 544

  Fly   594 IQPNEACTFIDEILTTMSSII------CDLQPQQVHTFYEAVGYMISAQVDQVQQDVLIERYMQL 652
                        :||.::|::      ..|.|..:.....|.|:   |..|.|          .:
 Frog   545 ------------VLTNLASLLPLIAHAGHLMPLVLQKLLSAAGF---ADTDGV----------TV 584

  Fly   653 PNQVWDDIISRASKNVDFLKNMTAVKQLGSILKT-------NVAACKALGHAYVIQLGRIYLDML 710
            |..|..:|.|.|                |::|:|       .|..|..:.|..:..|
 Frog   585 PRTVLRNIRSCA----------------GTLLQTVCVTFPDLVGPCFEVLHTRIKAL-------- 625

  Fly   711 NVYKITSENIIQAIE---VNGVNV---NNQPLIKTMHVVKKETLN-----LISEWVSR------- 757
                :..|.::...|   :.|..|   |:.........:.:|.|.     |:||.:.|
 Frog   626 ----LGQERLLTGAERCALMGALVLASNHFKNYSRQRSILEELLRPAVSMLLSEEMQRVLSGPRE 686

  Fly   758 --------SNDNQLVMD-------NFIPPLLDAILLDYQRCKVPS------------AREP---- 791
                    .::||...|       :.:....|.:|...::.:.|:            .|.|
 Frog   687 FISFLNNPGSENQEEGDDGGRLSYSKLCYCADTLLAAIRKSRRPNQFTEATAGGFVKGRTPNGAV 751

  Fly   792 ----------KVLSAMAIIVHKLRQ-HITNEVPKIFDAVFECTLDMINKNFEDFPQHRLSFYELL 845
                      |||..:.:::..:.. ::...:.|:.:.|.:..|::.||:..|
 Frog   752 FLNPCAGELLKVLDRLLVLIRTMNSLYLPEVMTKMAETVCQSGLEVENKSIMD------------ 804

  Fly   846 QAVNAHCFKAFL--NIPPA----QFKLVFDSVVWA-----------FKHTMRNVADMGLNILFKM 893
                  |.:..:  ::||.    |.:..::|:..|           ..|...:|.|:...:|...
 Frog   805 ------CSQPIMGESVPPVTVPEQLQGPYNSLYKACCQILGKCGPSMPHEFYSVPDLASRLLSSA 863

  Fly   894 LQNLDQHPGAAQSFYQTYFTDILMQIFSVVTDTSHTAGLPNHAIILAYMFSLVENRKITVNLGPI 958
            ..|||            |.:|:.::  .:|.|           ::...:|.....:..:|.| ||
 Frog   864 FTNLD------------YVSDLHLR--HIVND-----------LVTPLLFYCPSKKYESVVL-PI 902

  Fly   959 PDNMIFIQEYVASLLKSAFTHLSDNQVKVFVTGLFNLDENVQAFKEHLRDFLIQIREATGEDDSD 1023
                      :..||.|.:..||..                          .:.|.:.|...:.|
 Frog   903 ----------LRPLLMSLYQRLSQK--------------------------WLCINQRTTSSEED 931

  Fly  1024 LYLEEREA 1031
            |..||.|:
 Frog   932 LLEEESES 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
emb	NP_001303316.1	CRM1	13..1023	CDD:227432	197/1103 (18%)
		IBN_N	43..109	CDD:197981	13/41 (32%)
		Xpo1	120..265	CDD:285575	32/154 (21%)
		CRM1_C	701..1015	CDD:285920	57/390 (15%)
xpo5.2	XP_031757698.1	CRM1	58..>376	CDD:227432	85/357 (24%)
		Xpo1	116..267	CDD:400614	32/153 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D40069at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010