DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Acp29AB and SFTPA2

DIOPT Version :9

Sequence 1:	NP_523512.2	Gene:	Acp29AB / 34162	FlyBaseID:	FBgn0015583	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	XP_005270185.1	Gene:	SFTPA2 / 729238	HGNCID:	10799	Length:	265	Species:	Homo sapiens

Alignment Length:	161	Identity:	33/161 - (20%)
Similarity:	62/161 - (38%)	Gaps:	28/161 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 AQMEIQLQPLKIIMRHHASNIKASNNIK---MRRFEKVGSRHFHIEKNLMQTWFEA-YVTCRKMN 143
            |.::.:||......||.....:.:.:::   |...|||.|      .|.....|:| ...|.:..
Human   118 AHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFS------SNGQSITFDAIQEACARAG 176

  Fly   144 GHLANIQDEMELDGILALAPN-NSY-WIDISKLVENG------GTFVSTLTGREPFFVKWKSNQD 200
            |.:|..::..|.:.|.:.... |:| ::.:::....|      ||.|:        :..|...:.
Human   177 GRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVN--------YTNWYRGEP 233

  Fly   201 T-KKKNQCVYIYAKEMSYD-ECFEKKSFVCQ 229
            . :.|.|||.:|......| .|...:..:|:
Human   234 AGRGKEQCVEMYTDGQWNDRNCLYSRLTICE 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acp29AB	NP_523512.2	CLECT	121..229	CDD:214480	22/118 (19%)
SFTPA2	XP_005270185.1	Collagen	45..117	CDD:189968
SFTPA2	XP_005270185.1	CLECT_collectin_like	153..265	CDD:153061	27/126 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000