DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Acp29AB and SFTPD

DIOPT Version :9

Sequence 1:	NP_523512.2	Gene:	Acp29AB / 34162	FlyBaseID:	FBgn0015583	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_003010.4	Gene:	SFTPD / 6441	HGNCID:	10803	Length:	375	Species:	Homo sapiens

Alignment Length:	153	Identity:	32/153 - (20%)
Similarity:	64/153 - (41%)	Gaps:	9/153 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 AQMEIQLQPLKIIMRHHASNIKASNNIKM-RRFEKVGSRHFHIEKNLMQTWFEAYVTCRKMNGHL 146
            |.:..|::.|:..::|..:.......::: ...:.||.:.|. ....::.:.||.:.|.:..|.|
Human   225 ASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFK-TAGFVKPFTEAQLLCTQAGGQL 288

  Fly   147 ANIQDEMELDGI--LALAPNNSYWIDISKLVENGGTFVSTLTGREPFFVKWKSNQ--DTKKKNQC 207
            |:.:...|...:  |.:|.|.:.::.::. .:..|.|... ||....:..|...:  |......|
Human   289 ASPRSAAENAALQQLVVAKNEAAFLSMTD-SKTEGKFTYP-TGESLVYSNWAPGEPNDDGGSEDC 351

  Fly   208 VYIYAKEMSYDE-CFEKKSFVCQ 229
            |.|:......|. |.||:..||:
Human   352 VEIFTNGKWNDRACGEKRLVVCE 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acp29AB	NP_523512.2	CLECT	121..229	CDD:214480	25/112 (22%)
SFTPD	NP_003010.4	Collagen	46..98	CDD:189968
		Collagen	130..201	CDD:189968
		Surfac_D-trimer	224..269	CDD:286141	7/44 (16%)
		CLECT_collectin_like	262..375	CDD:153061	26/116 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910