DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Acp29AB and Clec12a

DIOPT Version :9

Sequence 1:	NP_523512.2	Gene:	Acp29AB / 34162	FlyBaseID:	FBgn0015583	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_808354.1	Gene:	Clec12a / 232413	MGIID:	3040968	Length:	267	Species:	Mus musculus

Alignment Length:	254	Identity:	52/254 - (20%)
Similarity:	97/254 - (38%)	Gaps:	75/254 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QQDIPNGKATLPSPQTPQNTI-----------DQIGINQNYWFTYNALKQNETLAIIDTMEMRIA 75
            :.|...||.:..:..:.|.|:           ..:|:....::|        |||    .|| |.
Mouse    23 KSDKCGGKVSADASHSQQKTVLILILLCLLLFIGMGVLGGIFYT--------TLA----TEM-IK 74

  Fly    76 SSLLEFKAQMEIQLQPLKIIMRHHASNIKASNNI----------------------KMRRFEKVG 118
            |:.|: :|:.|:| :.:.:.::|:.::.|...|:                      |.:...| |
Mouse    75 SNQLQ-RAKEELQ-ENVSLQLKHNLNSSKKIKNLSAMLQSTATQLCRELYSKEPEHKCKPCPK-G 136

  Fly   119 SRHF----HIEKNLMQTWFEAYVTCRKMNGHLANIQDEMELDGI---------LALAPNNSYWID 170
            |..:    :.:.|...||.|:.:.|...|..|..::::..|:.|         |||.|..    |
Mouse   137 SEWYKDSCYSQLNQYGTWQESVMACSARNASLLKVKNKDVLEFIKYKKLRYFWLALLPRK----D 197

  Fly   171 ISKLVENGGTFVSTLTGREPFFVKWKSNQDTKKKNQCVYIYAKEMSYDECFEKKSFVCQ 229
            .::...:...|:|..:.|        |..|..|| .|.||....:.|..|.::.:.:|:
Mouse   198 RTQYPLSEKMFLSEESER--------STDDIDKK-YCGYIDRVNVYYTYCTDENNIICE 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acp29AB	NP_523512.2	CLECT	121..229	CDD:214480	26/120 (22%)
Clec12a	NP_808354.1	ITIM motif	5..10
Clec12a	NP_808354.1	CLECT_NK_receptors_like	133..247	CDD:153063	29/127 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1201127at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010