DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Acp29AB and COLEC10

DIOPT Version :9

Sequence 1:	NP_523512.2	Gene:	Acp29AB / 34162	FlyBaseID:	FBgn0015583	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_006429.2	Gene:	COLEC10 / 10584	HGNCID:	2220	Length:	277	Species:	Homo sapiens

Alignment Length:	161	Identity:	39/161 - (24%)
Similarity:	65/161 - (40%)	Gaps:	26/161 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 EFKAQMEIQLQPLKIIMRHHASNIKASNNIKMRRFEKVGSRHFHI---EKNLMQTWFEAYVTCRK 141
            :|..|::|.:..||..|: ...|:.|.    :|..|:   :.::|   |||    :.|:...||.
Human   126 KFVGQLDISIARLKTSMK-FVKNVIAG----IRETEE---KFYYIVQEEKN----YRESLTHCRI 178

  Fly   142 MNGHLANIQDEMELDGILALAPNNSY---WIDISKLVENGGTFVSTLTGREPF--FVKWKSNQ-- 199
            ..|.||..:||.....|......:.:   :|.::.| |..|.::  .|...|.  :..|...:
Human   179 RGGMLAMPKDEAANTLIADYVAKSGFFRVFIGVNDL-EREGQYM--FTDNTPLQNYSNWNEGEPS 240

  Fly   200 DTKKKNQCVYIYAKEMSYD-ECFEKKSFVCQ 229
            |......||.:.:.....| ||.....|||:
Human   241 DPYGHEDCVEMLSSGRWNDTECHLTMYFVCE 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acp29AB	NP_523512.2	CLECT	121..229	CDD:214480	28/118 (24%)
COLEC10	NP_006429.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	40..107
		Collagen	45..111	CDD:189968
		CLECT_collectin_like	157..272	CDD:153061	29/125 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100086
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810