DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and Slc32a1

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_113970.1	Gene:	Slc32a1 / 83612	RGDID:	621402	Length:	525	Species:	Rattus norvegicus

Alignment Length:	497	Identity:	115/497 - (23%)
Similarity:	196/497 - (39%)	Gaps:	114/497 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 DYEGSRGSAARPVRSSPPDNTLVNVHSEDSLAASGSGDDEIGSTDK--------SYNPTHHRDLE 93
            |....||.|  |:   ||..      |:|....:|.   |.|..||        .:|.|:...
  Rat    82 DIHYQRGGA--PL---PPSG------SKDQAVGAGG---EFGGHDKPKITAWEAGWNVTNAIQ-- 130

  Fly    94 HPTSNFDTLVHLLKGNIGTGILAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRF 158
                             |..:|.:|.|..:.| |:|||..:....:|.:...:|:.|.:|.....
  Rat   131 -----------------GMFVLGLPYAILHGG-YLGLFLIIFAAVVCCYTGKILIACLYEENEDG 177

  Fly   159 QQPSLDFSEVAYCSFESGPLGLRRYSMLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMDHYYK 223
            :...:..|.||..:....|    |:..|..|:|.....| ::...|:.::.|:.|:  :.:.:..
  Rat   178 EVVRVRDSYVAIANACCAP----RFPTLGGRVVNVAQII-ELVMTCILYVVVSGNL--MYNSFPG 235

  Fly   224 MPV--QIYLLIMLGPMILLNLVRNLKYLTPVSLVAALLTVAGLAITFSYMLVDLPDVHTVKPVAT 286
            :||  :.:.:|....::....::|||.::..||:..|.......:..:|.|....|
  Rat   236 LPVSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARD--------- 291

  Fly   287 WA-----------TLPLYFGTAIYAFEGIGVVLP-LENNMRTPEDFGGTTGVLNTGMVIVACLYT 339
            ||           ..|:..|..::::.. .:.|| ||.||:.|.:|    ..:.....|.||:..
  Rat   292 WAWEKVKFYIDVKKFPISIGIIVFSYTS-QIFLPSLEGNMQQPSEF----HCMMNWTHIAACVLK 351

  Fly   340 AVGFF---GYLKYGEHVEGSITLNLPQGDTLSQLVRISMAVAIFLSYTLQFYVPVNIVEPFV--- 398
              |.|   .||.:.:..:..||.|||  .::..:|.|.:.....|||.|.|:..|.::|..:
  Rat   352 --GLFALVAYLTWADETKEVITDNLP--GSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQE 412

  Fly   399 --RSHFDTT-----RAKDLSATVLRVVLVTFTFLLATCIPNLGSIISLVGAVSSSALALIAPPII 456
              |:.|...     |.|....| ||..||.||.|:|..:|:...::.|.|:::.:.|..:.|.:.
  Rat   413 GSRAFFPACYGGDGRLKSWGLT-LRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLF 476

  Fly   457 EVITFYNVGYGRFNW--MLWKDV-----LILIFGLC---GFV 488
            .:         |..|  :||..|     :.:|.|:|   |||
  Rat   477 HL---------RLLWRKLLWHQVFFDVAIFVIGGICSVSGFV 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	94/425 (22%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	99/432 (23%)
Slc32a1	NP_113970.1	Aa_trans	115..512	CDD:279788	101/450 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352536
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740