DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and SLC38A1

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001265319.1	Gene:	SLC38A1 / 81539	HGNCID:	13447	Length:	503	Species:	Homo sapiens

Alignment Length:	486	Identity:	103/486 - (21%)
Similarity:	192/486 - (39%)	Gaps:	95/486 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DLTPLTNLQQIPEGAPRKKKMTERQPLLLQSDASDY-EGSRGSA-ARPVRSSPPDNTLVNVHSED 65
            :||.|.|: .:||...            :.:|::|: |...|.. ::.:.......:|.|.|.|.
Human     9 ELTELQNM-TVPEDDN------------ISNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEK 60

  Fly    66 SLAASGSGDDEIGSTDKSYNPTHHRDLEHPTSNFDTLVHLLKGNIGTGILAMPDAFKNAGLYVGL 130
            ...     |:.|..|               ||...::.:|....:|:|||.:..|..|.|:.:.|
Human    61 KKC-----DEYIPGT---------------TSLGMSVFNLSNAIMGSGILGLAFALANTGILLFL 105

  Fly   131 FGTMIMGAICTHCMHMLVNCSHEL-CRRFQQPSLDFSEVAYCSFESGPLGLRRYSMLARRIVTTF 194
            .....:..:..:.:::|:.||.|. |..:::                 ||.:.:....:.::...
Human   106 VLLTSVTLLSIYSINLLLICSKETGCMVYEK-----------------LGEQVFGTTGKFVIFGA 153

  Fly   195 LFITQIGFCCVYFLFVALN-----IKDVM------DHYYKMPVQIYLLIMLGPMILLNLVRNLKY 248
            ..:...| ..:.:||:..|     ||.:|      ..:|.....:.:::..|.::.|.|::||.|
Human   154 TSLQNTG-AMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGY 217

  Fly   249 LTPVSLVAALLTVAGLAITFSYMLVDLP-----------------DVHTVKPVATWATLPLY-FG 295
            |...|..:....|..|.:.. |....:|                 |..|.|.| |:.:..:| ..
Human   218 LGYTSGFSLSCMVFFLIVVI-YKKFQIPCIVPELNSTISANSTNADTCTPKYV-TFNSKTVYALP 280

  Fly   296 TAIYAFEGIGVVLPLENNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLN 360
            |..:||.....|||:.:.::.... .....|.|.....:..:|.....||||.:.::|:..: |:
Human   281 TIAFAFVCHPSVLPIYSELKDRSQ-KKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDL-LH 343

  Fly   361 LPQG--DTLSQLVRISMAVAIFLSYTLQFY-VPVNIVEPFVRSHFDTTRAKDLSATVLRVVLVTF 422
            ..|.  |.|...||:::.||:.|:..:.|: |..::.|...::.|:..|     .||:..:|:..
Human   344 KYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFNLCR-----HTVVTCILLVV 403

  Fly   423 TFLLATCIPNLGSIISLVGAVSSSALALIAP 453
            ..||...||::..|..:||..|::.|..|.|
Human   404 INLLVIFIPSMKDIFGVVGVTSANMLIFILP 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	86/395 (22%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	86/393 (22%)
SLC38A1	NP_001265319.1	SLC5-6-like_sbd	69..480	CDD:382020	87/408 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158644
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750