DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and slc32a1

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001074170.1	Gene:	slc32a1 / 798575	ZFINID:	ZDB-GENE-061201-1	Length:	530	Species:	Danio rerio

Alignment Length:	519	Identity:	108/519 - (20%)
Similarity:	202/519 - (38%)	Gaps:	120/519 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 DASDYEGSRGSAARPVRSSPPDNTLVNVHSEDSLAASGS---GDDEIGSTDKSYN-------PTH 88
            |..||:..:|             ..:::...|.:...|.   |:|.:...|..|.       |:.
Zfish    52 DDLDYDHRQG-------------LQMDILKNDEMGGEGGGEMGEDGMAEGDSHYQRDGTGPPPSA 103

  Fly    89 HRD--LEHPTSNFD-----------TLVHLLKGNIGTGILAMPDAFKNAGLYVGLFGTMIMGAIC 140
            .:|  |.....|.|           .:.:.::|..   :|.:|.|..:.| |:|||..:....:|
Zfish   104 SKDGGLCSEIGNPDKPRITAWEAGWNVTNAIQGMF---VLGLPYAILHGG-YLGLFLIIFAAVVC 164

  Fly   141 THCMHMLVNCSHE-----LCRRFQQPSLDFSEVAYCSFESGPLGLRRYSMLARRIVTTFLFITQI 200
            .:...:|:.|.:|     ...|.:...:|.:. |.|:        .|:..|...:|.....| ::
Zfish   165 CYTGKILIACLYEENEDGQLVRVRDSYVDIAN-ACCA--------PRFPALGGHVVNVAQII-EL 219

  Fly   201 GFCCVYFLFVALNIKDVMDHYYKMPV--QIYLLIMLGPMILLNLVRNLKYLTPVSLVAALLTVAG 263
            ...|:.::.|:.|:  :.:.:..:||  :.:.:|....::....::|||.::..||:..|.....
Zfish   220 VMTCILYVVVSGNL--MYNSFPTLPVSQRSWAIIATAALLPCAFLKNLKAVSKFSLLCTLAHFVI 282

  Fly   264 LAITFSYMLVDLPDVHTVKPVATWA-----------TLPLYFGTAIYAFEGIGVVLP-LENNMRT 316
            ..:..:|.|....|         ||           ..|:..|..::::.. .:.|| ||.||:.
Zfish   283 NILVIAYCLSRARD---------WAWDKVKFYIDVKKFPISIGIIVFSYTS-QIFLPSLEGNMQK 337

  Fly   317 PEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQGDTLSQLVRISMAVAIFL 381
            |.:|.......:....|:..|:..|   .||.:.:..:..||.|||  .::..:|.:.:.....|
Zfish   338 PSEFHCMMNWTHIAACILKGLFALV---AYLTWADETKEVITDNLP--SSIRAVVNLFLVSKALL 397

  Fly   382 SYTLQFYVPVNIVEPFV-----RSHFDTTRAKD-------LSATVLRVVLVTFTFLLATCIPNLG 434
            ||.|.|:..|.::|...     |:.|......|       ||   ||..||.||.|:|..:|:..
Zfish   398 SYPLPFFAAVEVLEKTFFQDGGRAFFPDCYGGDGRLKSWGLS---LRCALVVFTMLMAIYVPHFA 459

  Fly   435 SIISLVGAVSSSALALIAPPIIEVITFYNVGYGRFNW--MLWKDV-----LILIFGLC---GFV 488
            .::.|.|:::.:.|..:.|.:..:         :..|  :||..|     :.:|.|:|   ||:
Zfish   460 LLMGLTGSLTGAGLCFLLPSLFHL---------KLLWRKLLWHQVFFDVAIFVIGGICSISGFI 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	92/440 (21%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	95/447 (21%)
slc32a1	NP_001074170.1	Aa_trans	120..517	CDD:279788	93/438 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594481
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740