DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and Slc38a10

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	XP_006534347.1	Gene:	Slc38a10 / 72055	MGIID:	1919305	Length:	1111	Species:	Mus musculus

Alignment Length:	430	Identity:	86/430 - (20%)
Similarity:	177/430 - (41%)	Gaps:	91/430 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 TSNFDTLVHLLKGNIGTGILAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCS---HELCRR 157
            ||.:..:.:::...:|..:|.||..||..|:        ::||:      :||.||   |:.| .
Mouse     6 TSKWGLITNVVNSIVGVSVLTMPFCFKQCGI--------VLGAL------LLVFCSWMTHQSC-M 55

  Fly   158 FQQPSLDFSE-VAYCSFESGPLGLRRYSMLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMDHY 221
            |...|...|: ..|..     |....|....:.:|.|.:....:|.|..:::.:.    |:..::
Mouse    56 FLVKSASLSKRRTYAG-----LAFHAYGKAGKMLVETSMIGLMLGSCITFYVVIG----DLGSNF 111

  Fly   222 Y--------KMPVQIYLLIMLGPMIL--LNLVRNLKYLTPVSLVAALLTVAGLAITF--SYMLVD 274
            :        ...|:::||..:...|:  |:|.||        ::|::.:.:.:|:.|  .:|.|.
Mouse   112 FAPLLGLQVTRTVRVFLLFAVSLFIVLPLSLQRN--------MMASIQSFSAMALLFYTVFMFVI 168

  Fly   275 --------------LPDVHTVKPVATWATLPLYFGTAIYAFEGIGVVLPLENNMRTPEDFGGTTG 325
                          |..|..::....:..:|: ||   .:|.....|||..:::..| .....:.
Mouse   169 VLSSLKHGLFSGQWLRQVSYIRWEGVFRCVPI-FG---MSFACQSQVLPTYDSLDEP-SVKTMSS 228

  Fly   326 VLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQGDTLSQLVRISMAVAIFLSYTLQFYVP 390
            :..:.:.:|...|..||||||:.:.:...|::.::.| .:.:::::|:...:::.:.:.:
Mouse   229 IFASSLNVVTAFYVMVGFFGYVSFTDATTGNVLIHFP-SNPVTEMIRVGFVMSVAVGFPM----- 287

  Fly   391 VNIVEP---------FVRSHFDTTRAKDLSATVLRVVLVTFTFLLAT-----CIPNLGSIISLVG 441
              ::.|         |.:...|.|.|.......||..::|.:.:..|     .|||:.:|:...|
Mouse   288 --MILPCRQALNTLLFEQQQKDGTFAAGGYMPPLRFKVLTLSVVFGTMVGGVMIPNVETILGFTG 350

  Fly   442 AVSSSALALIAPPIIEVITFYNVGYGRFNWMLWKDVLILI 481
            |...|.:..|.|.:|......|....:.  :||..:.||:
Mouse   351 ATMGSLICFICPALIYKKAHKNAPSAQV--VLWVGLGILV 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	86/430 (20%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	86/430 (20%)
Slc38a10	XP_006534347.1	SLC5-6-like_sbd	6..381	CDD:382020	82/421 (19%)
		PTZ00121	<407..789	CDD:173412
		PTZ00449	<731..>991	CDD:185628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810