DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and Slc38a4

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001344987.1	Gene:	Slc38a4 / 69354	MGIID:	1916604	Length:	547	Species:	Mus musculus

Alignment Length:	512	Identity:	103/512 - (20%)
Similarity:	193/512 - (37%)	Gaps:	140/512 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 HRDLEHP--TSNFDTLVHLLKGNIGTGILAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCS 151
            :.|..||  ||...:..:|....:|:|||.:..|..|.|:.:.:...:.:..:..:.:|:|:..:
Mouse    66 YADEHHPGMTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLTVAILSLYSVHLLLKTA 130

  Fly   152 HELCRRFQQPSLDFSEVAYCSFE-SGPLGLRRYSMLARRIVTTFLFIT--QIGFCCVYFLFVALN 213
            .|      ..||.:.::...:|. .|.:|             .|:.||  .||....|...:...
Mouse   131 KE------GGSLIYEKLGEKAFGWPGKIG-------------AFISITMQNIGAMSSYLFIIKYE 176

  Fly   214 IKDVM----------DHYYKMPVQIYLLIMLGPMILLNLVRNLKYL---TPVSLVAALLTVAGLA 265
            :.:|:          ..:|.....:.|.:.:|.::.|:|::||.||   :..||...:..|:.:.
Mouse   177 LPEVIRAFMGLEENTGEWYLNGNYLVLFVSVGIILPLSLLKNLGYLGYTSGFSLSCMVFFVSVVI 241

  Fly   266 -------------------ITFSYML----VDLPD-----------------------------V 278
                               :||:..|    :.||:                             :
Mouse   242 YKKFQIPCPLPALDHNNGNLTFNNTLPIHMISLPNDSESSGVNFMMDYAHHNPAGLDEKQVAGPL 306

  Fly   279 HT--VKPVATWA--TLPLYF----GTA------IYAFEGIGVVLPLENNM--RTPEDFGGTTGVL 327
            |:  |:..|..|  ..|.||    .||      .:||.....|||:.:.:  |:.......:.:.
Mouse   307 HSNGVEYEAQGAEKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNIS 371

  Fly   328 NTGMVIVACLYTAVGFFGYLKYGEHVEGSIT---LNLPQGDTLSQLVRISMAVAIFLSYTLQFYV 389
            .:||::   :|.....||||.:...||..:.   ..:...||...:||:::.||:.|:..:..:
Mouse   372 ISGMLV---MYLLAALFGYLSFYGDVEDELLHAYSKVYTFDTALLMVRLAVLVAVTLTVPIVLF- 432

  Fly   390 PVN---IVEPFVRSHFDTTRAKDLSATVLRVVLVTFTFLLATCIPNLGSIISLVGAVSSSALALI 451
            |:.   |...|.|..|...:...::|     :::....:|...:|.:..|...:||.|::.|..|
Mouse   433 PIRTSVITLLFPRKPFSWLKHFGIAA-----IIIALNNILVILVPTIKYIFGFIGASSATMLIFI 492

  Fly   452 APPIIEVITFYNVGYGRFNWMLWKDVL-------ILIFGLCGFVFGTWASLAQILND 501
            .|     ..||..       ::.|:.|       .|:|.:.|.:| ...|:|.|:.|
Mouse   493 LP-----AAFYLK-------LVKKEPLRSPQKIGALVFLVTGIIF-MMGSMALIILD 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	96/490 (20%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	98/499 (20%)
Slc38a4	NP_001344987.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34
Slc38a4	NP_001344987.1	SLC5-6-like_sbd	75..535	CDD:382020	99/500 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910