DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and slc38a2

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001038569.1	Gene:	slc38a2 / 566537	ZFINID:	ZDB-GENE-030131-9659	Length:	504	Species:	Danio rerio

Alignment Length:	485	Identity:	100/485 - (20%)
Similarity:	188/485 - (38%)	Gaps:	97/485 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 NPTHHRDLEHPTSNFDTLVHLLK---------------------GN--IGTGILAMPDAFKNAGL 126
            |...:.|:|..:.||.:..||.|                     ||  :|:|||.:..|..|.|:
Zfish    40 NGIQYSDVEAESQNFLSDHHLGKKKYEAEYSPGSASFGMSVFNLGNAIMGSGILGLSYAMANTGI 104

  Fly   127 YVGLFGTMIMGAICTHCMHMLVNCSHELCRRFQQPSLDFSEVAYCSF-------ESGPLGLRRYS 184
            .:.:...:.:.....:.:|:|:..::|      ..||.:.::.|.:|       .|..:.::.:.
Zfish   105 AMFVILLVAVAIFSLYSVHLLLKTANE------GGSLVYEQLGYKAFGIPGKLAASCSITMQNFG 163

  Fly   185 MLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMDH-YYKMPVQIYLLIMLGPMILLNLVRNLKY 248
            .:|     ::|:|.:.....|...|:     |..|: :|.....:.|::.:..::.|:|::||.|
Zfish   164 AMA-----SYLYIVKYELPIVIRAFL-----DSNDNAWYTNGDYLVLIVTMSIILPLSLLKNLGY 218

  Fly   249 LTPVSLVAALLTVAGLAITFSYMLVDLP----------DVHTVKPVAT------WATLPLYF--- 294
            |...|..:.|..|..|.:.. |....:|          .|:..:|..|      ....|.||
Zfish   219 LGYTSGFSLLCMVFFLIVVI-YKKFQIPCPLPENFINITVNVSQPPQTNNSTDEECCKPKYFIFN 282

  Fly   295 GTAIY-------AFEGIGVVLPLENNM--RTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYG 350
            ...:|       ||.....:||:...:  |:.........|...||.|   :|.....||||.:.
Zfish   283 SQTVYAVPILTFAFVCHPAILPMYEELKDRSRRKMQNVANVSFLGMFI---MYLLAALFGYLTFN 344

  Fly   351 EHVEGSI------TLNLPQGDTLSQLVRISMAVAIFLSYTLQFYVPVNIVEPFVRSHFDTTRAKD 409
            |.||..:      ..|.   |.:..:||:::..|:.|:..:..:.....|...:.:..:.:..:.
Zfish   345 EAVEPELLHTYSKVYNF---DVVLLIVRLAVLTAVTLTVPVVLFPIRTSVNHLLGASKEFSWPRH 406

  Fly   410 LSATVLRVVLVTFTFLLATCIPNLGSIISLVGAVSSSALALIAPPIIEVITFYNVGYGRFNWMLW 474
            :..||..:|.|.   :|...:|.:..|...:||.:::.|..|.|.     .||.....:.:....
Zfish   407 ICITVALLVCVN---ILVIFVPTIRDIFGFIGASAAAMLIFILPS-----AFYIKLVKKESMKSV 463

  Fly   475 KDVLILIFGLCGFVFGTWASLAQILNDRTH 504
            :.:...:|.:.||:..| .|:|.|:.|..|
Zfish   464 QKIGATLFLIMGFLVMT-GSMALIIMDWIH 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	90/456 (20%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	92/465 (20%)
slc38a2	NP_001038569.1	Regulates protein turnover upon amino acid deprivation. /evidence=ECO:0000250	1..99		14/58 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		SdaC	70..479	CDD:223884	86/439 (20%)
		SLC5-6-like_sbd	72..488	CDD:294310	90/447 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594594
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750