DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and slc36a1

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	XP_021336836.1	Gene:	slc36a1 / 559308	ZFINID:	ZDB-GENE-061117-1	Length:	468	Species:	Danio rerio

Alignment Length:	450	Identity:	186/450 - (41%)
Similarity:	265/450 - (58%)	Gaps:	35/450 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 DEIGSTDKSYNPTHHRDLEHP-------TSNFDTLVHLLKGNIGTGILAMPDAFKNAGLYVGLFG 132
            ||..:.|:..:....|..|:.       :|...|::||||||||||:|.:|.|.:||||.||...
Zfish    17 DESPTEDEPIHSPGSRQTEYERIGGRTGSSVLQTIIHLLKGNIGTGLLGLPLAVRNAGLLVGPLS 81

  Fly   133 TMIMGAICTHCMHMLVNCSHELCRRFQQPSLDFSEVAYCSFESGPLGLRRYSMLARRIVTTFLFI 197
            .:|||.:..|||::||.|:|.|..:..:|.|.:.:......|: ...|.|:|:..|.:|..||.|
Zfish    82 LLIMGIVAVHCMNLLVKCAHHLSAKLGKPFLSYGDAVEYGMEN-VSWLSRHSIWGRHVVNLFLNI 145

  Fly   198 TQIGFCCVYFLFVALNIKDVMD-----------HYYKMPV-----QIYLLIMLGPMILLNLVRNL 246
            ||:|||||||:|::.|:|.|::           :...:||     ::|::..|..:|||..:|||
Zfish   146 TQLGFCCVYFVFLSDNVKQVVETANATTGNCHNNETAVPVPSYDSRLYMVFFLPFIILLVFIRNL 210

  Fly   247 KYLTPVSLVAALLTVAGLAITFSYMLVDLPDVHTVKPVATWATLPLYFGTAIYAFEGIGVVLPLE 311
            |||.|:|..|.:...|.|.:.:.|.|.::|:...:......|..||:|||||:||||||||||||
Zfish   211 KYLAPLSFAANICMCASLVLIYYYCLTNIPNPINLPLAGRGADYPLFFGTAIFAFEGIGVVLPLE 275

  Fly   312 NNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQGDTLSQLVRISMA 376
            |.|:.|.:|   |.||..||.||..||.::|..||:.:||.:.||||||||. ..|.|:|::..:
Zfish   276 NKMQNPRNF---TKVLYLGMGIVTFLYISLGTIGYIGFGEEIRGSITLNLPL-CWLYQIVKLLYS 336

  Fly   377 VAIFLSYTLQFYVPVNIVEP--FVRSHFDTTRAKDLSATVLRVVLVTFTFLLATCIPNLGSIISL 439
            ..|:::|.|||||...|:.|  ..|.........|||   :||.||..|..||..||.|..:|||
Zfish   337 FGIYITYALQFYVSAEILIPPAVARCGPRWALMVDLS---IRVALVGLTCALAILIPELDLVISL 398

  Fly   440 VGAVSSSALALIAPPIIEVITFYNVGYGRFNWMLWKDVLILIFGLCGFVFGTWASLAQIL 499
            ||:|||||||||.||::::|||:|....  .|:..||:||.:.|..||:.||:.|:.:|:
Zfish   399 VGSVSSSALALIIPPLLQIITFHNEDMK--PWVFAKDILISVLGFVGFIAGTYTSIQEIV 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	175/416 (42%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	179/425 (42%)
slc36a1	XP_021336836.1	SLC5-6-like_sbd	44..453	CDD:320982	180/418 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594523
Domainoid	1	1.000	309	1.000	Domainoid score	I1306
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	312	1.000	Inparanoid score	I2564
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm6436
orthoMCL	1	0.900	-	-		OOG6_100466
Panther	1	1.100	-	-	LDO	PTHR22950
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R126
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.900