DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and SLC38A7

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001356537.1	Gene:	SLC38A7 / 55238	HGNCID:	25582	Length:	462	Species:	Homo sapiens

Alignment Length:	507	Identity:	109/507 - (21%)
Similarity:	196/507 - (38%)	Gaps:	110/507 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LQSDASDYEGS--RGSAARPVRSSPPDNTLVNVHSEDSLAASGSGDDEIGSTDKSYNPTHHRDLE 93
            :.:|.|:::.|  .|..||.::|...|.           |.....:...|..|:.
Human     6 INNDYSEWDLSTDAGERARLLQSPCVDT-----------APKSEWEASPGGLDRG---------- 49

  Fly    94 HPTSNFDTLVHLLKGNIGTGILAMPDAFKNAG-------LYVGLFGTMIMGAICTHCMHMLVNCS 151
             .||....:..::...:|.|:|..|.||..||       |.:|:...:|.|.:      :|..||
Human    50 -TTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLV------ILAYCS 107

  Fly   152 HELCRRFQQPSLDFSEV--AYCSFESGPLGLRRYSMLARRIVTTFLFITQIGFCCVYFLFVALNI 214
            .....|      .:.||  |.|...:|        :|....:..:.|.|     |:.||.:..:.
Human   108 QASNER------TYQEVVWAVCGKLTG--------VLCEVAIAVYTFGT-----CIAFLIIIGDQ 153

  Fly   215 KD----VM-------------DHYYKMPVQIYLLIMLGPMILLNLVRNLKYLTPVSLVAALLTVA 262
            :|    ||             |..:.:.:..:|.|:  |:.:...:...||.:.:|:|......|
Human   154 QDKIIAVMAKEPEGASGPWYTDRKFTISLTAFLFIL--PLSIPREIGFQKYASFLSVVGTWYVTA 216

  Fly   263 GLAITFSYMLVDLPDVHTVKPVATWATLPLYFGTAIYAFEGIGVVLPLENNMRTPE--DFGGTTG 325
            .:.|.:.:...::...:.:...|:|..:.....|..:.|:.....:|:.|:|:.||  .:|   |
Human   217 IVIIKYIWPDKEMTPGNILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWG---G 278

  Fly   326 VLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQGDTLSQLVRISMAVAIFLSYTLQFYVP 390
            |:...|||...:|...|..|:|.:|..|:..:.|:.|..|....:.|..:.:::..||.:..:..
Human   279 VVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCG 343

  Fly   391 VNIVEPFVRSHFDTTRAKDLSATVLRVVLVT-----FTFLLATCIPNLGSIISLVGAVSS----- 445
            ..:||.....:......:|:.....|.||.|     .|.|||..||::|.:||::|.:::
Human   344 RAVVEGLWLRYQGVPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFV 408

  Fly   446 -SALALIAPPIIEV------ITFYNVGYGRFNWMLWKDVLILIFGLCGFVFG 490
             ..|.||...:.|:      ..:..|.||           :|:..|..|:||
Human   409 FPGLCLIQAKLSEMEEVKPASWWVLVSYG-----------VLLVTLGAFIFG 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	94/436 (22%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	98/442 (22%)
SLC38A7	NP_001356537.1	SLC5-6-like_sbd	49..457	CDD:320982	98/453 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158603
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750