Protein Alignment CG13384 and SLC38A2

DIOPT Version :9

• Sequence 1: NP_723383.1
• Gene: CG13384 / 34160
• FlyBaseID: FBgn0032036
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_061849.2
• Gene: SLC38A2 / 54407
• HGNCID: 13448
• Length: 506
• Species: Homo sapiens
• Alignment Length: 530
• Identity: 118/530 - (22%)
• Similarity: 209/530 - (39%)
• Gaps: 116/530 - (21%)

  Fly    51 SSPPDNTLVNVHSEDSLAASGSGDDEIG-STDKSYNPTHHRDLEHPTSNF-----------DTLV 103
            |..||        |||.:.|.:.|.... .|.::...:|:.|::....||           :|..
Human    10 SISPD--------EDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETEF 66

  Fly   104 H------------LLKGNIGTGILAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCR 156
            |            |....:|:|||.:..|..|.|:.:.:.....:.....:.:|:|:..::|
Human    67 HPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANE--- 128

  Fly   157 RFQQPSLDFSEVAYCSF-------ESGPLGLRRYSMLARRIVTTFLFITQIGFCCVYFLFVALNI 214
               ..||.:.::.|.:|       .||.:.::....:     :::|||.:.....|  :....||
Human   129 ---GGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAM-----SSYLFIVKYELPLV--IQALTNI 183

  Fly   215 KDVMDHYYKMPVQIYLLIMLGPMILLNLVRNLKYLTPVSLVAALLTVAGLAITF----------- 268
            :|....:|.....:.||:.|..::.|:|.|||.||...|.::.|..|..|.:..
Human   184 EDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVE 248

  Fly   269 -SYMLVDLPDVHTVKPVATWATL-----------PLYF----------GTAIYAFEGIGVVLPLE 311
             :.::.:..:....:|.|....|           |.||          ...|::|.....|||:.
Human   249 AALIINETINTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIY 313

  Fly   312 NNMRTPEDFGGTTGVLNTGMV---IVACLYTAVGFFGYLKYGEHVEGSI--TLNLPQG-DTLSQL 370
            ..::.    .....::|...:   .:..:|.....||||.:.||||..:  |.:...| |.|..:
Human   314 EELKD----RSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSSILGTDILLLI 374

  Fly   371 VRISMAVAIFLSYTLQFYVPVNIVEPFVRS---HFDTTRAKDLS---ATVLRVVLVTFTFLLATC 429
            ||:::.:|:.|:      ||| ::.| :||   |. ...:||.|   .:::.|.::.||.||...
Human   375 VRLAVLMAVTLT------VPV-VIFP-IRSSVTHL-LCASKDFSWWRHSLITVSILAFTNLLVIF 430

  Fly   430 IPNLGSIISLVGAVSSSALALIAPPIIEVITFYNVGYGRFNWMLWKDVLILIFGLCGFVFGTWAS 494
            :|.:..|...:||.::|.|..|.|.     .||.....:......:.:..|.|.|.|.:..| .|
Human   431 VPTIRDIFGFIGASAASMLIFILPS-----AFYIKLVKKEPMKSVQKIGALFFLLSGVLVMT-GS 489

  Fly   495 LAQILNDRTH 504
            :|.|:.|..|
Human   490 MALIVLDWVH 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	99/466 (21%)
		SLC5-6-like_sbd	94..495	CDD:294310	102/475 (21%)
SLC38A2	NP_061849.2	Regulates protein turnover upon amino acid deprivation. /evidence=ECO:0000250	1..96		20/93 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		7/20 (35%)
		SLC5-6-like_sbd	69..495	CDD:320982	101/457 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158646
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750