DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and slc36a4

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	XP_002664741.3	Gene:	slc36a4 / 504109	ZFINID:	ZDB-GENE-050309-239	Length:	488	Species:	Danio rerio

Alignment Length:	457	Identity:	181/457 - (39%)
Similarity:	263/457 - (57%)	Gaps:	37/457 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 ASGSGDDEIGSTDKSYNPTHHRDLEHPTSNFDTLVHLLKGNIGTGILAMPDAFKNAGLYVGLFGT 133
            |.|..::|..:.|...:..|   |....:...||:||||||||||:|.:|.|.||||:.:|....
Zfish    19 AEGEEEEEDENVDGDEDSKH---LPQGITFTQTLLHLLKGNIGTGLLGLPLAVKNAGIVLGPVSL 80

  Fly   134 MIMGAICTHCMHMLVNCSHELCRRFQQPSLDFSEVAYCSFE-SGPLGLRRYSMLARRIVTTFLFI 197
            ::||.:|.||||:||||||:|..|.::..|.:||....:.| |....|||.:...|.:|..||.:
Zfish    81 VLMGVVCVHCMHILVNCSHQLSERLKRSPLGYSETVAAAMELSSSQCLRRSAHFGRHLVNFFLVL 145

  Fly   198 TQIGFCCVYFLFVALNIKDVMDHYY-----------------------KMPVQIYLLIMLGPMIL 239
            ||:|||.|||:|:|.|||.||:..:                       .:.:::|::.:|..:|:
Zfish   146 TQLGFCSVYFVFLAENIKQVMEGTHMNSTAETVLLSSNSSEASVASSVAIDLRLYMVFLLPFIIV 210

  Fly   240 LNLVRNLKYLTPVSLVAALLTVAGLAITFSYMLVDLPDVHTVKPVATWATLPLYFGTAIYAFEGI 304
            |..:|:|:.:..:|.:|.|.....|...|||:|.||.|...:...:||...|.:|||||:|||||
Zfish   211 LTFIRDLRNMAALSAIANLCMAISLIFIFSYILNDLSDPRRLPYASTWRKFPFFFGTAIFAFEGI 275

  Fly   305 GVVLPLENNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQGDTLSQ 369
            ||||||||.||.|:.|   ...||.||..:..||..:...|||::.:.::||||||||.....:|
Zfish   276 GVVLPLENQMREPKRF---PQALNIGMGFIIVLYVTLATLGYLRFRDDIKGSITLNLPHDSWSNQ 337

  Fly   370 LVRISMAVAIFLSYTLQFYVPVNIVEPFV--RSHFDTTRAKDLSATVLRVVLVTFTFLLATCIPN 432
            ||::..:..:|:|:.:||:||..|:.|.:  |......|..|||   ||.:||..|.:.|..||.
Zfish   338 LVKVLYSFGVFVSFAVQFFVPAEILLPPMCERVRKSWRRVADLS---LRALLVCLTCVTAVLIPR 399

  Fly   433 LGSIISLVGAVSSSALALIAPPIIEVITFYNVGYGRFNWMLWKDVLILIFGLCGFVFGTWASLAQ 497
            |..:||||||||||||||:.||::|:|.|.:......  :|.||:.|...|..||:.||:.::.:
Zfish   400 LDLVISLVGAVSSSALALVFPPLVELIAFPSQPPPPM--LLLKDISIAALGFIGFLTGTYVTVEE 462

  Fly   498 IL 499
            |:
Zfish   463 II 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	170/417 (41%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	174/426 (41%)
slc36a4	XP_002664741.3	SLC5-6-like_sbd	42..460	CDD:294310	174/425 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594558
Domainoid	1	1.000	309	1.000	Domainoid score	I1306
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56300
Inparanoid	1	1.050	312	1.000	Inparanoid score	I2564
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm6436
orthoMCL	1	0.900	-	-		OOG6_100466
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R126
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.940