DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13384 and CG7888

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	195/463 - (42%)
Similarity:	278/463 - (60%)	Gaps:	32/463 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 NVHSEDS----------LAASGSGDDEIGSTDKSYNPTHHRDLEHPTSNFDTLVHLLKGNIGTGI 114
            |.||..:          ||..|..:..:.:.|..|||.||||:||||:|.:||.|||||::||||
  Fly     7 NGHSNSAYVADHPDKLELAEKGQKNKAVVAKDPDYNPYHHRDVEHPTTNSETLFHLLKGSLGTGI 71

  Fly   115 LAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRFQQPSLDFSEVAYCSFESGPLG 179
            ||||:||:|:|...|..||:::|.|||.|:|.||...:|||||.:.||:::..||..:...||..
  Fly    72 LAMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAETAMGEGPKC 136

  Fly   180 LRRYSMLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMDHY--YKMPVQIYLLIMLGPMILLNL 242
            .|.::.....:|.|||.|.|:|.||||.:|||.|||.::|..  ..:.|::.::|:|.|:||:|.
  Fly   137 FRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTSIDVRLCMIIILLPLILINW 201

  Fly   243 VRNLKYLTPVSLVAALLTVAGLAITFSYMLVDLPDVHTVKPVATW--------ATLPLYFGTAIY 299
            |||||||.|.|.:|..:|:....|...|:..:        ||.|.        :..||:|||.::
  Fly   202 VRNLKYLAPFSTLANAITMVSFGIICYYIFRE--------PVTTEGKDAFGKPSNFPLFFGTVLF 258

  Fly   300 AFEGIGVVLPLENNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQG 364
            |.|.|||:|||||.|:||:.|||:.||||..||::..||..:|.||||.||..|.||||||:|:.
  Fly   259 ALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITLNMPEH 323

  Fly   365 DTLSQLVRISMAVAIFLSYTLQFYVPVNIV-EPFVRSHFDTTRAKDLSATVLRVVLVTFTFLLAT 428
            :.||..|:..:|.||::::.|..||.::|. ..:|.......|........:|..||..|||||.
  Fly   324 EVLSMCVKGMLAFAIYITHGLACYVAIDITWNDYVAKRLGAQRNALFWEYAVRTGLVLITFLLAV 388

  Fly   429 CIPNLGSIISLVGAVSSSALALIAPPIIEVIT-FYNV-GYGRFNWMLWKDVLILIFGLCGFVFGT 491
            .||||...|||.||:..|||.|..|.:|::.| :||. |:.:. |::..:.:::|.|:.|.|.||
  Fly   389 AIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKV-WLVLSNFVLIIVGILGLVIGT 452

  Fly   492 WASLAQIL 499
            :.||.:|:
  Fly   453 YTSLKEIV 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	173/404 (43%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	177/413 (43%)
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	176/410 (43%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	170/402 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468318
Domainoid	1	1.000	157	1.000	Domainoid score	I1306
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1622
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm8749
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
	10	9.900