DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and Slc38a2

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	XP_006242344.1	Gene:	Slc38a2 / 29642	RGDID:	69420	Length:	535	Species:	Rattus norvegicus

Alignment Length:	555	Identity:	118/555 - (21%)
Similarity:	202/555 - (36%)	Gaps:	169/555 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 EDSLAASGSGDDEIG-STDKSYNPTHHRDLEHPTSNFDTLVHLLKGN------------------ 109
            |||.:.|.:||.... .|.::...:|:.|::....||     ||:.|
  Rat    15 EDSSSYSSNGDFNYSYPTKQAALKSHYVDVDPENQNF-----LLESNLGKKKYETDFHPGTTSFG 74

  Fly   110 ----------IGTGILAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRFQQPSLD 164
                      :|:|||.:..|..|.|:.:.:.....:.....:.:|:|:..::|      ..||.
  Rat    75 MSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANE------GGSLL 133

  Fly   165 FSEVAYCSFESGPLGLRRYSMLARRIVTTFLFITQIGFCCVYFLFV----------ALNIKDVMD 219
            :.:          ||.:.|.:..:...:..:.:..||....|...|          .:||:|...
  Rat   134 YEQ----------LGHKAYGLAGKLAASGSITMQNIGAMSSYLFIVKYELPLVIKALMNIEDTNG 188

  Fly   220 HYYKMPVQIYLLIMLGPMILLNLVRNLKYL---TPVSLVAAL--LTVAGLAI------------- 266
            .:|.....:.||:....::.|:|:|||.||   :.:||:..:  |.|.|:.:
  Rat   189 LWYLNGDYLVLLVSFVLILPLSLLRNLGYLGYTSGLSLLCMIFFLIVVGVVVFVCRKCILKALSG 253

  Fly   267 --------TFSYML------------VDLPDVHTVKPVATWATL--------------PLYF--- 294
                    .|...:            |.|....||....|...|              |.||
  Rat   254 HPALLTSAIFCCQVICKKFQIPCPVEVALMANETVNGTFTQVALAALASNSTAADTCRPRYFIFN 318

  Fly   295 GTAIYA-------FEGIGVVLPLENNMRTPEDFGGTTGVLNTGMV---IVACLYTAVGFFGYLKY 349
            ...:||       |.....|||:...:::    .....::|...:   .:..:|.....||||.:
  Rat   319 SQTVYAVPILTFSFVCHPAVLPIYEELKS----RSRRRMMNVSKISFFAMFLMYLLAALFGYLTF 379

  Fly   350 GEHVEGSI--TLNLPQG-DTLSQLVRISMAVAIFLSYTLQFYVPVNIVEPFVRS---HFDTTRAK 408
            .||||..:  |.:...| |.|..:||:::.||:.|:      ||| ::.| :||   |. ....|
  Rat   380 YEHVESELLHTYSAIVGTDILLLVVRLAVLVAVTLT------VPV-VIFP-IRSSVTHL-LCPTK 435

  Fly   409 DLS---ATVLRVVLVTFTFLLATCIPNLGSIISLVGAVSSSALALIAPPIIEVITFY-------- 462
            :.|   .:|:.|.::.||.||...:|.:..|...:||.:::.|..|.|.     .||
  Rat   436 EFSWFRHSVITVTILAFTNLLVIFVPTIRDIFGFIGASAAAMLIFILPS-----AFYIKLVKKEP 495

  Fly   463 -----NVGYGRFNWMLWKDVLILIFGLCGFVFGTW 492
                 .:|...|   |...|:::| |..|.:...|
  Rat   496 MRSVQKIGALCF---LLSGVVVMI-GSMGLIVLDW 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	106/516 (21%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	109/524 (21%)
Slc38a2	XP_006242344.1	SdaC	64..516	CDD:223884	100/488 (20%)
Slc38a2	XP_006242344.1	SLC5-6-like_sbd	69..518	CDD:294310	101/486 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352652
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750