DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and Slc36a2

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_694810.2	Gene:	Slc36a2 / 246049	MGIID:	1891430	Length:	478	Species:	Mus musculus

Alignment Length:	473	Identity:	191/473 - (40%)
Similarity:	273/473 - (57%)	Gaps:	42/473 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 ARPVRSSPPDNTLVNVHSEDSLAASGSGDDEIGSTDKSYNPTHHRDLEHPTSNFDTLVHLLKGNI 110
            |.|:....|::. ..:.|:|...|:||..:   |:.|:...|          .|.|||||:|||:
Mouse    13 ATPLNLDLPESA-KKLQSQDPSPANGSSSE---SSKKTKGIT----------GFQTLVHLVKGNM 63

  Fly   111 GTGILAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRFQQPSLDFSEVAYCSFES 175
            |||||.:|.|.||||:.:|....::||.|..||||:||.|:...|.|..:|.:|:.:........
Mouse    64 GTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRLNKPFMDYGDTVMHGLAF 128

  Fly   176 GP-LGLRRYSMLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMD---------HYYK------- 223
            .| ..|:.::...||:|:.||.:||:||||||.:|:|.|:|.|::         |..:
Mouse   129 SPNAWLQNHAHWGRRVVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNETVVLTPT 193

  Fly   224 MPVQIYLLIMLGPMILLNLVRNLKYLTPVSLVAALLTVAGLAITFSYMLVDLPDVHTVKPVATWA 288
            |..::|:|..|..:.||..||||:.||..||:|.:..:..|.|...|::.::||...:..||:|.
Mouse   194 MDSRLYMLSFLPVLGLLVFVRNLRVLTIFSLLANISMLVSLVIIAQYIIQEIPDASQLPLVASWK 258

  Fly   289 TLPLYFGTAIYAFEGIGVVLPLENNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHV 353
            |.||:|||||::||.|||||||||.|:   |..|...:|:.||.|:..||.|:|..|||::|:.:
Mouse   259 TYPLFFGTAIFSFESIGVVLPLENKMK---DARGFPTILSLGMSIITTLYIAIGALGYLRFGDDI 320

  Fly   354 EGSITLNLPQGDTLSQLVRISMAVAIFLSYTLQFYVPVNIVEPFVRSHFDTTRA--KDLSATVLR 416
            :.||||||| ...|.|.|::...|.|..:|.||||||..|:.|...|......|  .|||   :|
Mouse   321 KASITLNLP-NCWLYQSVKLLYVVGILCTYALQFYVPAEIIIPLAVSQVSKRWALPVDLS---IR 381

  Fly   417 VVLVTFTFLLATCIPNLGSIISLVGAVSSSALALIAPPIIEVITFYNVGYGRFNWMLWKDVLILI 481
            :.||..|.:||..||.|..::||||:|||||||||.||::||:|:|..|.....  :.||.||.|
Mouse   382 LALVCLTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVVTYYGEGISPLT--VTKDALISI 444

  Fly   482 FGLCGFVFGTWASLAQIL 499
            .|..|||.||:.:|.:::
Mouse   445 LGFMGFVVGTYQALDELI 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	173/410 (42%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	179/419 (43%)
Slc36a2	NP_694810.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..46		9/36 (25%)
Slc36a2	NP_694810.2	SLC5-6-like_sbd	48..458	CDD:294310	180/428 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849008
Domainoid	1	1.000	317	1.000	Domainoid score	I1261
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2472
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm8749
orthoMCL	1	0.900	-	-		OOG6_100466
Panther	1	1.100	-	-	LDO	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770