DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and Slc36a1

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_694779.3	Gene:	Slc36a1 / 215335	MGIID:	2445299	Length:	475	Species:	Mus musculus

Alignment Length:	468	Identity:	192/468 - (41%)
Similarity:	275/468 - (58%)	Gaps:	44/468 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 DNTLVNVHSEDSLAASGSGDDEIGSTDKSYNPTHHRDLEHPTSN--FDTLVHLLKGNIGTGILAM 117
            |.:..:|..|:| .:.|.|         |::|..::.|...:|.  |.||:||||||||||:|.:
Mouse    13 DYSSTDVSPEES-PSEGLG---------SFSPGSYQRLGENSSMTWFQTLIHLLKGNIGTGLLGL 67

  Fly   118 PDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRFQQPSLDFSEVAYCSFESGP-LGLR 181
            |.|.|||||.:|....:::|.:..|||.:||.|:|.||||..:|.||:.:......|..| ..:|
Mouse    68 PLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRLNKPFLDYGDTVMYGLECSPSTWVR 132

  Fly   182 RYSMLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMDHYY----------------KMPVQIYL 230
            .:|...||||..||.:||:|||||||:|:|.|.|.|::...                .|..::|:
Mouse   133 NHSHWGRRIVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTTNCNNNVTVIPTPTMDSRLYM 197

  Fly   231 LIMLGPMILLNLVRNLKYLTPVSLVAALLTVAGLAITFSYMLVDLPDVHTVKPVATWATLPLYFG 295
            |..|..::||:.:|||:.|:..||:|.:.....|.:.:.:::..:||...:..||.|.|.||:||
Mouse   198 LSFLPFLVLLSFIRNLRVLSIFSLLANISMFVSLIMIYQFIVQRIPDPSHLPLVAPWKTYPLFFG 262

  Fly   296 TAIYAFEGIGVVLPLENNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLN 360
            |||:|||||||||||||.|:..:.|   ..:|..||.|:..||.::|..|||::|.:::||||||
Mouse   263 TAIFAFEGIGVVLPLENKMKDSQKF---PLILYLGMAIITVLYISLGSLGYLQFGANIKGSITLN 324

  Fly   361 LPQGDTLSQLVRISMAVAIFLSYTLQFYVPVNIVEPFVRS----HFDTTRAKDLSATVLRVVLVT 421
            || ...|.|.|::..::.||.:|.|||||...|:.|.:.|    ||:.  ..||   .:|..:|.
Mouse   325 LP-NCWLYQSVKLLYSIGIFFTYALQFYVAAEIIIPAIVSRVPEHFEL--MVDL---CVRTAMVC 383

  Fly   422 FTFLLATCIPNLGSIISLVGAVSSSALALIAPPIIEVITFYNVGYGRFNWMLWKDVLILIFGLCG 486
            .|.:||..||.|..:|||||:|||||||||.||::||:|:|..|.....  :.||.||.|.|..|
Mouse   384 VTCVLAILIPRLDLVISLVGSVSSSALALIIPPLLEVVTYYGEGISPLT--VTKDALISILGFVG 446

  Fly   487 FVFGTWASLAQIL 499
            ||.||:.||.:::
Mouse   447 FVVGTYESLCELI 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	176/414 (43%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	181/423 (43%)
Slc36a1	NP_694779.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32		6/28 (21%)
Slc36a1	NP_694779.3	SLC5-6-like_sbd	47..452	CDD:294310	179/415 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848962
Domainoid	1	1.000	317	1.000	Domainoid score	I1261
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2472
Isobase	1	0.950	-	0	Normalized mean entropy	S2463
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm8749
orthoMCL	1	0.900	-	-		OOG6_100466
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R126
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.750