DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13384 and Slc36a3

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_758462.2	Gene:	Slc36a3 / 215332	MGIID:	2665001	Length:	477	Species:	Mus musculus

Alignment Length:	470	Identity:	180/470 - (38%)
Similarity:	267/470 - (56%)	Gaps:	44/470 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 NVHSEDSLAASGSGDDEIGSTDKSYNPTHHRDLEHPTSNFDTL------VHLLKGNIGTGILAMP 118
            |:....:.::.||      |..:|.:.|..:  :.|....|.|      :||||.|||||.|.:|
Mouse    16 NMFGRSTASSKGS------SNSRSSSSTSPK--KGPRREADALMFIQIFIHLLKSNIGTGFLGLP 72

  Fly   119 DAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRFQQPSLDFSEVAYCSFESGPL-GLRR 182
            .|.|||||.||....:.:||:..|||.:|:||:..|.:|.|:..:::.|....|.|:.|. .||.
Mouse    73 LAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTQRLQRSFVNYEETTMYSLETCPSPWLRT 137

  Fly   183 YSMLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMD--HYYK--------------MPVQIYLL 231
            :|:..|.:|:..|.:||:|||.|||:|:|.|::.:|:  |:..              :..:.|:|
Mouse   138 HSVWGRYVVSFLLIVTQLGFCSVYFMFLADNLQQIMEEAHFTSNVCQPRQSLVMTSILDTRFYML 202

  Fly   232 IMLGPMILLNLVRNLKYLTPVSLVAALLTVAGLAITFSYMLVDLPDVHTVKPVATWATLPLYFGT 296
            .:|..:|||.|::|.:.|:..|.:|.:.|::.||:.|.| |:..|....:..||.|.|..|:|||
Mouse   203 TILPFLILLVLIQNPQVLSIFSTLATITTLSSLALIFEY-LIQTPHHSNLPLVANWKTFLLFFGT 266

  Fly   297 AIYAFEGIGVVLPLENNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNL 361
            ||:.|||:|:||||::.|::|:.|   ..||..||..|..||..:|..||:|:|...:.||||||
Mouse   267 AIFTFEGVGMVLPLKSQMKSPQQF---PAVLYLGMSFVIFLYICLGTLGYMKFGTDTQASITLNL 328

  Fly   362 PQGDTLSQLVRISMAVAIFLSYTLQFYVPVNIVEPFVRSHFDTTRAKDLSATVLRVVLVTFTFLL 426
            |. ..|.|.|::..:|.||.:|.|||:||..|:.|:|.|......|..:..|| |..||..|...
Mouse   329 PI-CWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPYVVSRVSENWALFVDLTV-RTALVCLTCFS 391

  Fly   427 ATCIPNLGSIISLVGAVSSSALALIAPPIIEVITFY--NVGYGRFNWMLWKDVLILIFGLCGFVF 489
            |..||.|..:|||||:|||||||:|.||::|:.|||  |:...    .:.||::|.|.||.|.|.
Mouse   392 AVLIPRLDLVISLVGSVSSSALAIIIPPLLEIATFYSENISCA----TIVKDIMISILGLLGCVL 452

  Fly   490 GTWASLAQILNDRTH 504
            ||:.:|.: :..:||
Mouse   453 GTYQALYE-MTQQTH 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	165/416 (40%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	171/425 (40%)
Slc36a3	NP_758462.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..43		5/31 (16%)
Slc36a3	NP_758462.2	SLC5-6-like_sbd	52..458	CDD:382020	168/415 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849015
Domainoid	1	1.000	317	1.000	Domainoid score	I1261
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2472
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm8749
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.870