DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and Slc38a4

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_570104.1	Gene:	Slc38a4 / 170573	RGDID:	621836	Length:	547	Species:	Rattus norvegicus

Alignment Length:	580	Identity:	114/580 - (19%)
Similarity:	213/580 - (36%)	Gaps:	175/580 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 RPVRSSPPDNTLVNVHSEDSLAA--SGSGDDEIGSTDKSY-------------------NPTHHR 90
            |.|...|.:::.    |.||:.:  :|.|:.|.|:.|..:                   ..|.:.
  Rat     7 RSVNIEPYEDSC----SVDSIQSCYTGMGNSEKGAMDSQFANEDAESQKFLTNGFLGKKTLTDYA 67

  Fly    91 DLEHP-TSNFD-TLVHLLKGNIGTGILAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHE 153
            |..|| |::|. :..:|....:|:|||.:..|..|.|:.:.:...:.:..:..:.:|:|:..:.|
  Rat    68 DEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIVLFVIMLLTVAILSLYSVHLLLKTAKE 132

  Fly   154 LCRRFQQPSLDFSEVAYCSFE-SGPLGLRRYSMLARRIVTTFLFIT--QIGFCCVYFLFVALNIK 215
                  ..||.:.::...:|. .|.:|             .|:.||  .||....|...:...:.
  Rat   133 ------GGSLIYEKLGEKAFGWPGKIG-------------AFISITMQNIGAMSSYLFIIKYELP 178

  Fly   216 DVM----------DHYYKMPVQIYLLIMLGPMILLNLVRNLKYL---TPVSLVAALLTVAGLA-- 265
            :|:          ..:|.....:.|.:.:|.::.|:|::||.||   :..||...:..|:.:.
  Rat   179 EVIRVFMGLEENTGEWYLNGNYLVLFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYK 243

  Fly   266 -----------------ITFSYML-------------------VDL----PDVHTVKPVATWATL 290
                             :||:..|                   ||.    |:....||.|.
  Rat   244 KFQIPCPLPVLDHNNGNLTFNNTLPMHVIMLPNNSESTGMNFMVDYTHRDPEGLDEKPAAG---- 304

  Fly   291 PLYFGTAI-----------------------------YAFEGIGVVLPLENNM--RTPEDFGGTT 324
            ||: |:.:                             :||.....|||:.:.:  |:.......:
  Rat   305 PLH-GSGVEYEAHSGDKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVS 368

  Fly   325 GVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSIT---LNLPQGDTLSQLVRISMAVAIFLSYTLQ 386
            .:..|||::   :|.....||||.:...||..:.   ..:...||...:||:::.||:.|:..:.
  Rat   369 NISITGMLV---MYLLAALFGYLSFYGEVEDELLHAYSKVYTFDTALLMVRLAVLVAVTLTVPIV 430

  Fly   387 FYVPVN---IVEPFVRSHFDTTRAKDLSATVLRVVLVTFTFLLATCIPNLGSIISLVGAVSSSAL 448
            .: |:.   |...|.|..|...:...::|     :::....:|...:|.:..|...:||.|::.|
  Rat   431 LF-PIRTSVITLLFPRRPFSWVKHFGIAA-----IIIALNNVLVILVPTIKYIFGFIGASSATML 489

  Fly   449 ALIAPPIIEVITFYNVGYGRFNWMLWKDVL-------ILIFGLCGFVFGTWASLAQILND 501
            ..|.|     ..||..       ::.|:.|       .|:|.:.|.:| ...|:|.|:.|
  Rat   490 IFILP-----AAFYLK-------LVKKEPLRSPQKIGALVFLVTGIIF-MMGSMALIIID 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	95/495 (19%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	97/504 (19%)
Slc38a4	NP_570104.1	SLC5-6-like_sbd	73..535	CDD:382020	98/507 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910