DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13384 and slc38a5a

DIOPT Version :9

Sequence 1:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	XP_001344749.1	Gene:	slc38a5a / 100005797	ZFINID:	ZDB-GENE-081105-92	Length:	491	Species:	Danio rerio

Alignment Length:	499	Identity:	104/499 - (20%)
Similarity:	190/499 - (38%)	Gaps:	113/499 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 VNVHSE----DSLAASGSGDDEIGSTDKSYNPTHHRDLEHPTSNFDTLVHLLKGNIGTGILAMPD 119
            :|:..|    |:|.....||..:.|.......|...|.|..||...::.:|....:|:|||.:..
Zfish    16 MNLEKEFTGFDALENMAEGDQFLSSKSNGKIETQFTDFEGKTSFGMSIFNLSNAIMGSGILGLAY 80

  Fly   120 AFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRFQQPSLDFSEVAYCSFESGPLGLRRYS 184
            |..|.|:.:.:|..:.:..:.::.:|:|:.                        .:|.:|:|.|.
Zfish    81 AMANTGIILFVFLLITIALLSSYSIHLLLR------------------------SAGVVGIRAYE 121

  Fly   185 MLARRIVTT--------FLFITQIGFCCVYFLFVALNIKDVMDHYYKMPVQI--------YLLIM 233
            .|..|...|        .:.:..||....|...|.:.:..|::....:|...        ||:|:
Zfish   122 QLGYRAFGTPGKVVAGCIITLHNIGAMSSYLFIVKIELPHVIEGLTGLPDNSGHWYVDGRYLIII 186

  Fly   234 LGPMIL--LNLVRNLKYL-------------TPVSLVAALLTVAGL--------AITFS--YMLV 273
            :...::  |.|::.|.||             ..:|::...|:.:|:        ..|||  .|:.
Zfish   187 VSVCVIFPLALMKRLGYLGYTSGFSLSCMVFFLISVIYKCLSNSGIDSESNQNEKCTFSNASMIS 251

  Fly   274 DLPDVH--------------TVKPVATWATLPLYFGTAIYAFEGIGVVLPLENNMRTPEDFGGTT 324
            ...:::              |:.| .|..|:|:    ..:||.....|||:...::.|.. ....
Zfish   252 STTEINEINSTTEICEAKLLTINP-QTAFTIPI----IAFAFVCHPEVLPIYTELKNPSK-KQMQ 310

  Fly   325 GVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQGDTLSQLVRISMAVAIFLSYTLQFYV 389
            .|.|..::.:..:|.....||||.:..:|:..:.....:.|.|...||:::.||:.|:      |
Zfish   311 KVANISILAMFVMYLLTAIFGYLTFFANVDSELLKMYNKNDILMLCVRLAVLVAVTLT------V 369

  Fly   390 PVNIVEP---------FVRSHFDTTRAKDLSATVLRVVLVTFTFLLATCIPNLGSIISLVGAVSS 445
            || ::.|         |....|...|     ..::.:.|:....||...:||:..|...:||.|:
Zfish   370 PV-VLFPIRRAVLQLLFPEKPFSWVR-----HIIIAMCLLFAVNLLVIFVPNIRDIFGFIGATSA 428

  Fly   446 SALALIAPPIIEVITFYNVGYGRFNWMLWKDVLILIFGLCGFVF 489
            .:|..|.|.|..:   |.|...:........:|.::|...||:|
Zfish   429 PSLIFILPGIFYI---YIVPEEQEPLKSRPKILAILFVTLGFIF 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	92/455 (20%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	94/460 (20%)
slc38a5a	XP_001344749.1	SdaC	55..479	CDD:223884	94/460 (20%)
slc38a5a	XP_001344749.1	SLC5-6-like_sbd	55..479	CDD:294310	94/460 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594596
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750