Protein Alignment AlaRS and AlaRS-m

DIOPT Version :10

• Sequence 1: NP_523511.2
• Gene: AlaRS / 34156
• FlyBaseID: FBgn0027094
• Length: 966
• Species: Drosophila melanogaster
• Sequence 2: NP_523932.2
• Gene: AlaRS-m / 38595
• FlyBaseID: FBgn0028962
• Length: 1012
• Species: Drosophila melanogaster
• Alignment Length: 1057
• Identity: 349/1057 - (33%)
• Similarity: 520/1057 - (49%)
• Gaps: 153/1057 - (14%)

  Fly     2 KLLTAKEVRNAYLDFFK-EQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGT-ADPNSEMSK 64
            ::|||:|:|..:||.|. ...|.:|.||..:|..|||:.|.||||||||.:|||| |.|:.
  Fly    10 RVLTAREIRKTFLDHFTVNHGHKFVRSSPVVPFCDPTVAFVNAGMNQFKSVFLGTAAAPHK---- 70

  Fly    65 WVRVANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPK 129
              ||.|:|||:|.|||||||..||.|.|||||||||||||||||||:|.|:.|.|.|.....:..
  Fly    71 --RVVNSQKCVRVGGKHNDLSVVGTDGYHHTFFEMLGNWSFGDYFKREACAMALELLRGPYNIDP 133

  Fly   130 DRLYVTYFGGDAASGLEPDLECKQMWLDLGLKPEHILPGSMKDNFWEMGETGPCGPCSELHFDR- 193
            .|||||||.||...|:..||||.::|..||.....|||....|||||||.|||||||:|:|.|.
  Fly   134 GRLYVTYFAGDKVLGIPADLECFEIWRSLGFPASRILPFGCADNFWEMGATGPCGPCTEIHIDHR 198

  Fly   194 --IGGRSVPE---LVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGFERLVSVIQNK 253
              :|  ||.:   |||....|:.|:||||||||||.:|||:.|||..|:|.|||||||.:|:|||
  Fly   199 PDLG--SVEQRAKLVNAGRSDLTELWNLVFIQYNRHADGSISQLPAHHVDTGMGFERLTAVLQNK 261

  Fly   254 RSNYDTDLFVPLFDAIQAGTGAPPYQGRVGADDVDG-----IDMAYRVLADHARTITIALADGGT 313
            .||||||||.|:||.||.....|.|.|..    .||     :|.:||:||||||.:|..||||..
  Fly   262 SSNYDTDLFTPIFDGIQQAAKTPVYSGSF----PDGGNAAVLDTSYRILADHARMVTACLADGML 322

  Fly   314 PDNTGRGYVLRRILRRAVRYATEKLNAKPGFFATLVNTVVDLLGDAFPEVKKDPQHIIDII-NEE 377
            ||...:   |||:||:|:. .:|.:.|.......||..||:.||:|:||:....|.:||:| :|:
  Fly   323 PDQNQK---LRRVLRKALN-ISEHVFAHDKLLTQLVPIVVETLGEAYPEMAAKQQAVIDLICHEQ 383

  Fly   378 EL----------QFLKTLTRGRNL-------------LNRTIE----KLGNQTTIPGDVAWRLYD 415
            |:          .|.:.|....||             ..|.::    |..| .|||||..::|.|
  Fly   384 EVYKNLRESSSKAFAEVLMEFPNLDDIDLMECPGFVPAYRELQMQRCKFSN-NTIPGDFLYKLTD 447

  Fly   416 TYGFPVDLTQLMAEEKSLKIDMDGYEA--------AKHNSYVLSQGKGASKIEEINLDVHAISQL 472
            |||...:....:||.:::..|::.|.|        ||.|....:.|.......|..: ..|.:.|
  Fly   448 TYGLTEESFLKLAELENMNCDLERYRAEVSLAKLKAKGNQRETAGGSLCDLATEQRI-AEAQAML 511

  Fly   473 QEQGVPPTNDTFKYKYEAVSDERDSAYNYGVCNSKIVALRFENQFVNEITSGQK--------AGI 529
            .:: :.||:::.||.|.  .|:...:|......::::.:...:..|:. |.|.:        ..|
  Fly   512 TKR-LTPTDNSHKYTYS--FDKESDSYQIPPLKTRVLGMLLNDAEVSR-TQGSRIQQPFTDLISI 572

  Fly   530 VLDKTNFYAESGGQIYDQGALVKVN----DEANEFLVDRVYNRGGYILHIGVVEG-----TLKVG 585
            |...:|||.|||||..|.|.::..|    |..:...|..|.:....::||..:..     .|.:|
  Fly   573 VTAGSNFYYESGGQQSDGGKILVSNHQQPDHPHSLDVIGVKHLNDCVVHICKLSSPTDAFQLAIG 637

  Fly   586 DELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTEQKGSLVVPEKLRFDFNSKAAMTIEQVS 650
            ||:||.:|.::|.|...:|:|||.||..:..:..|.|.|..|.|..::.:.:.    .:..:::.
  Fly   638 DEVELQVDAQQRQLNTCHHTATHLLNAAIRSLFKKVTYQVSSSVSSDQCKLEL----GLLGKRIQ 698

  Fly   651 KTE-QLTKEMVYKNV----PIYAKESKLALAKKIRGLRSVFDEVYPDP-VRVISFGVPVDELEQN 709
            ||: ||.::::.:.:    |:..:....|...:...:..|..||||:. :|::           |
  Fly   699 KTDVQLIEDLINRVICSAAPVEVQLLSAAEVLEQNDITMVPGEVYPEQGLRLV-----------N 752

  Fly   710 PDSEAGEQTSVEFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAFEQEI 774
            .:|...:.:|.|.|.|||...:..:..|.|.:.:...:......|:.|..|...||.:......:
  Fly   753 VESPELQLSSKELCCGTHATNTSELSCFCIVNLKQTNRARFAFTAVAGQAAENVLKTAALLRHRV 817

  Fly   775 VRLKATIDNDKSGKDSKSHVKEIVELTEQISHATI--PYV-KKDEMRNLLKGLKKTLDDKERALR 836
            ..|:.....||....:::   |:..:...:.|..|  ||. |.|.:..:.:.||:..|.....|:
  Fly   818 DLLEKQFQTDKLTNATEA---ELQTIRHNMLHTDIKLPYAFKMDTLERITEMLKRIKDSSRTTLK 879

  Fly   837 AAVSVTVVERAKTLCEANP-----------NATVLVEQLEAFNNTKALDAALKQVRSQLPDAAAM 890
            ..|.|.:    :||.:..|           .::.|||::           .|::.....||...:
  Fly   880 EFVDVEM----RTLLQEKPLDTHPFILHYITSSALVEEI-----------PLQRATKLCPDRPIL 929

  Fly   891 FLSVDADSKKIFCLSSVPKSAVEKGLKANEWVQHVSATLGGK----GGGKPESA------QASGT 945
            .:||.....|..|  .||:..:.:...|:.|:|..:.|..|:    .|..|::.      :.|..
  Fly   930 VISVCDSVVKARC--CVPEKCITEKFNASAWLQSFADTFNGQIAAPKGQNPQAVCNMKGRRVSNL 992

  Fly   946 NYEKVDEIVQLASKFAQ 962
            ..|::::.:..|..:|:
  Fly   993 FEEQLEQAMSKAHAYAK 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AlaRS	NP_523511.2	PLN02900	5..963	CDD:215487	348/1054 (33%)
AlaRS-m	NP_523932.2	PLN02900	13..1010	CDD:215487	348/1054 (33%)