Protein Alignment AlaRS and aars1

DIOPT Version :10

• Sequence 1: NP_523511.2
• Gene: AlaRS / 34156
• FlyBaseID: FBgn0027094
• Length: 966
• Species: Drosophila melanogaster
• Sequence 2: NP_001037775.1
• Gene: aars1 / 324940
• ZFINID: ZDB-GENE-030131-3663
• Length: 991
• Species: Danio rerio
• Alignment Length: 966
• Identity: 581/966 - (60%)
• Similarity: 726/966 - (75%)
• Gaps: 11/966 - (1%)

  Fly     4 LTAKEVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPNSEMSKWVRV 68
            |||.::|..::|||:..:|.|||||:||||||||||||||||||||||||.|.||:..|::..|.
Zfish    30 LTAAQIREKFIDFFRRHEHQYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMARLRRA 94

  Fly    69 ANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPKDRLY 133
            |||||||||||||||||||||||||||||||||:||||||||...|..|.|.|||...:|.:|||
Zfish    95 ANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKHLACKMALELLTQEFGIPIERLY 159

  Fly   134 VTYFGGDAASGLEPDLECKQMWLDLGLKPEHILPGSMKDNFWEMGETGPCGPCSELHFDRIGGRS 198
            ||||||.|.:||||||||||:|||||::...||||||||||||||:|||||||||:|:||||||.
Zfish   160 VTYFGGHADAGLEPDLECKQIWLDLGMEESRILPGSMKDNFWEMGDTGPCGPCSEIHYDRIGGRD 224

  Fly   199 VPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGFERLVSVIQNKRSNYDTDLFV 263
            ...|||||||:|||||||||||:||||:..||.||||.||.|||.||||||:|||.|||||||||
Zfish   225 AAHLVNMDDPNVLEIWNLVFIQFNRESETVLKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFV 289

  Fly   264 PLFDAIQAGTGAPPYQGRVGADDVDGIDMAYRVLADHARTITIALADGGTPDNTGRGYVLRRILR 328
            |.|:|||.||||..|.|:|||:|.|||||||||||||||||||||:|||.|||||||||||||||
Zfish   290 PYFEAIQKGTGARAYTGKVGAEDTDGIDMAYRVLADHARTITIALSDGGRPDNTGRGYVLRRILR 354

  Fly   329 RAVRYATEKLNAKPGFFATLVNTVVDLLGDAFPEVKKDPQHIIDIINEEELQFLKTLTRGRNLLN 393
            |||||:.|||.|:.||||:||:.||..|||||||::|||..:.|||||||.||||||:|||.:|:
Zfish   355 RAVRYSHEKLGAQRGFFASLVDVVVKSLGDAFPELRKDPDMVKDIINEEEAQFLKTLSRGRRILD 419

  Fly   394 RTIEKLGNQTTIPGDVAWRLYDTYGFPVDLTQLMAEEKSLKIDMDGYEAAKHNSYVLSQGKGASK 458
            |.|:.||..||||||.||.||||||||:|||.|:|||:.:.:|:..:|..|..:.:.|||||:..
Zfish   420 RKIQSLGESTTIPGDTAWLLYDTYGFPLDLTALIAEERGMGVDLLAFEEEKKAAQLKSQGKGSGD 484

  Fly   459 IEEINLDVHAISQLQEQGVPPTNDTFKYKYEAVSDERDSAYNYGVCNSKIVALRFENQFVNEITS 523
            .:.|.||::||.:|:.:||..|:|:.||||  .||:..: |.:......::|||.|..||:|:.:
Zfish   485 EDHIMLDIYAIDELRNKGVAATDDSPKYKY--TSDDNGN-YEFEQAVGTVLALRRERMFVDEVIT 546

  Fly   524 GQKAGIVLDKTNFYAESGGQIYDQGALVKVNDEAN---EFLVDRVYNRGGYILHIGVVEGTLKVG 585
            ||:.|::||||:||||.|||.:|:|.:::.||.|.   ||.|.....||||:||||.|.||||||
Zfish   547 GQECGVLLDKTSFYAEQGGQSFDEGYMLRENDSAEDRMEFTVKNTQVRGGYVLHIGTVYGTLKVG 611

  Fly   586 DELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTEQKGSLVVPEKLRFDFNSKAAMTIEQVS 650
            |.|.||:|..||...|.||:|||.||:.|..||| :.:|:||||.|::|||||.:|.||:.::|.
Zfish   612 DRLTLHVDEARRRPIMSNHTATHILNYGLRSVLG-EADQRGSLVAPDRLRFDFTAKGAMSTDEVR 675

  Fly   651 KTEQLTKEMVYKNVPIYAKESKLALAKKIRGLRSVFDEVYPDPVRVISFGVPVDELEQNPDSEAG 715
            :||::...|:.....:||.::.||.||.|:|||:||||.|||||||:|.||||:||..:|:|.||
Zfish   676 RTEEIAAAMIADAKGVYALDAPLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVEELLADPNSPAG 740

  Fly   716 EQTSVEFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAFEQEIVRLKAT 780
            ..||:||||||||:.|.|...|||.||||||||||||||:||.||.||.:|::|.:   :.|.|.
Zfish   741 SLTSIEFCGGTHLQNSSHAAPFVIVSEEAIAKGIRRIVAVTGAEAQKAQRKADALK---LSLDAL 802

  Fly   781 IDNDKSGK-DSKSHVKEIVELTEQISHATIPYVKKDEMRNLLKGLKKTLDDKERALRAAVSVTVV 844
            .:..|:.. .:|...|||.::||.:..|.|...:|||||..||||||.:||.:||.:|.|...|:
Zfish   803 AEKVKAQSIPNKDVQKEIADMTESLGTAVISQWRKDEMRESLKGLKKIMDDLDRASKADVQKRVL 867

  Fly   845 ERAKTLCEANPNATVLVEQLEAFNNTKALDAALKQVRSQLPDAAAMFLSVDADSKKIFCLSSVPK 909
            |:.|.:.::|||..::|.::|:..:.|||:.:||.:::..|..|||..:||.|:.||.||..||:
Zfish   868 EKTKEIIDSNPNQPLIVMEMESGASAKALNESLKMLKTNSPQTAAMLFTVDNDAGKIICLCQVPQ 932

  Fly   910 SAVEKGLKANEWVQHVSATLGGKGGGKPESAQASGTNYEKVDEIVQLASKFAQSKL 965
            ....:||||:||||.|...|.||||||..||||:|.|.:.:.|.:||||:||:.||
Zfish   933 DVANRGLKASEWVQEVCPLLDGKGGGKDMSAQATGRNTQCIQEALQLASEFARLKL 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AlaRS	NP_523511.2	PLN02900	5..963	CDD:215487	578/961 (60%)
aars1	NP_001037775.1	PLN02900	31..984	CDD:215487	576/959 (60%)