Protein Alignment CG17294 and HDHD5

DIOPT Version :10

• Sequence 1: NP_609219.1
• Gene: CG17294 / 34155
• FlyBaseID: FBgn0032032
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_149061.1
• Gene: HDHD5 / 27440
• HGNCID: 1843
• Length: 423
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 75/337 - (22%)
• Similarity: 113/337 - (33%)
• Gaps: 114/337 - (33%)

  Fly     5 GALIDLSGTLHVEDEPTPNAVEALKRLRDS----GVLVKFVTNT---TKDSKATLHERLCRIGFQ 62
            |.|:|:.|.|.......|.|::|.:||.:|    .|.|.||||.   .:.|||  .|....:|.:
Human    48 GFLLDIDGVLVRGHRVIPAALKAFRRLVNSQGQLRVPVVFVTNAGNILQHSKA--QELSALLGCE 110

  Fly    63 LDASEI---YSSLSAAVSYVENERL----NPY-----------YILSEDARQDFPPED----TRR 105
            :||.::   :|.:.....|.|...|    .|.           .:..::.|..||..|    .||
Human   111 VDADQVILSHSPMKLFSEYHEKRMLVSGQGPVMENAQGLGFRNVVTVDELRMAFPLLDMVDLERR 175

  Fly   106 YKDSVV----------IGLAPKAFNYE-QLNEAFNVLLEN-------------------KNHKLI 140
            .|.:.:          :.|..:...:| .|....:|||.|                   .|..|:
Human   176 LKTTPLPRNDFPRIEGVLLLGEPVRWETSLQLIMDVLLSNGSPGAGLATPPYPHLPVLASNMDLL 240

  Fly   141 AVHQGKYYKRAEGLALGPGCFVKGLEF----ATGRTAK---VIGKPN--PYFFEGALAGRDP--- 193
            .:.:.|..:      .|.|.|:..||.    .||:..:   ::|||:  .|.:...|..|..
Human   241 WMAEAKMPR------FGHGTFLLCLETIYQKVTGKELRYEGLMGKPSILTYQYAEDLIRRQAERR 299

  Fly   194 ------ASCVMIGDDANDDIV---------------GAMSMGMQG--------------ILVKTG 223
                  .....:||:...|:.               ||..:|..|              |||.||
Human   300 GWAAPIRKLYAVGDNPMSDVYGANLFHQYLQKATHDGAPELGAGGTRQQQPSASQSCISILVCTG 364

  Fly   224 KYLPDVKPSPPP 235
            .|.|....|..|
Human   365 VYNPRNPQSTEP 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17294	NP_609219.1	HAD_PPase	4..250	CDD:319812	75/337 (22%)
HDHD5	NP_149061.1	CECR5	47..360	CDD:200106	66/319 (21%)