DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17294 and lhpp

DIOPT Version :9

Sequence 1:	NP_609219.1	Gene:	CG17294 / 34155	FlyBaseID:	FBgn0032032	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_002937837.3	Gene:	lhpp / 100498369	XenbaseID:	XB-GENE-955676	Length:	270	Species:	Xenopus tropicalis

Alignment Length:	263	Identity:	90/263 - (34%)
Similarity:	152/263 - (57%)	Gaps:	10/263 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SIKGALIDLSGTLHVE-----DEPTPNAVEALKRLRDSGVLVKFVTNTTKDSKATLHERLCRIGF 61
            :::..|:|:||.|:..     ......:|:|:.|:|.:|:.::|.||.::.:::...::|.|.||
Frog     7 NVRAVLLDVSGVLYDSGGSGGGSAIQGSVDAVNRIRQAGLKLRFCTNESQATRSHFAQKLQRFGF 71

  Fly    62 QLDASEIYSSLSAAVSYVENERLNPYYILSEDARQDFPPEDTRRYKDSVVIGLAPKAFNYEQLNE 126
            .:...|:.:...||...::.:.|.|:.::.:|...:|...:|.. .:.|:||.|.:.|:|:.:|.
Frog    72 SISKEEVTAPGPAATRLMKEQGLRPHLLVHDDLLPEFESIETSD-PNCVLIGDAAENFSYQNVNR 135

  Fly   127 AFNVLLENKNHKLIAVHQGKYYKRAEGLALGPGCFVKGLEFATGRTAKVIGKPNPYFFEGAL--A 189
            ||.||:..:...||::.:|:|||..:||.|..|.::|.||:|....|:|:|||:|.||..||  .
Frog   136 AFQVLINLQKPVLISLGKGRYYKETDGLKLDVGAYMKALEYACDIKAEVVGKPSPNFFLSALEEM 200

  Fly   190 GRDPASCVMIGDDANDDIVGAMSMGMQGILVKTGKYLPDVKPSPPPTA--LLENFAEAVDWIIQK 252
            |..|...||||||..:||.||.|.|::.:||:||||.|..:..|..||  .::|.|.|||.::..
Frog   201 GAKPEEAVMIGDDIVNDIGGAQSCGIRAVLVRTGKYRPSDEKHPEVTADGYVDNLAHAVDILLAS 265

  Fly   253 NQS 255
            ..|
Frog   266 RAS 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17294	NP_609219.1	HAD-SF-IIA-hyp3	3..251	CDD:162372	89/256 (35%)
		Hydrolase_6	7..98	CDD:290083	23/95 (24%)
		DUF843	<84..136	CDD:114536	16/51 (31%)
		Hydrolase_like	175..245	CDD:289983	35/73 (48%)
lhpp	XP_002937837.3	HAD_PPase	9..263	CDD:319812	89/254 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	61	1.000	Domainoid score	I10288
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D535833at33208
OrthoFinder	1	1.000	-	-		FOG0002535
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010