DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17294 and hdhd2

DIOPT Version :9

Sequence 1:	NP_609219.1	Gene:	CG17294 / 34155	FlyBaseID:	FBgn0032032	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001120092.1	Gene:	hdhd2 / 100145104	XenbaseID:	XB-GENE-977915	Length:	259	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	122/253 - (48%)
Similarity:	168/253 - (66%)	Gaps:	7/253 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IKGALIDLSGTLHVEDEPTPNAVEALKRLRDSGVLVKFVTNTTKDSKATLHERLCRIGFQLDASE 67
            :|..|:||||||||||...|.|.|||:|||::.|.::|||||||:.|.||.|||.::.|.:...|
Frog     7 LKAVLVDLSGTLHVEDTAIPGAQEALRRLREAPVALRFVTNTTKECKQTLLERLHQLNFDIQEDE 71

  Fly    68 IYSSLSAAVSYVENERLNPYYILSEDARQDFPPEDTRRYKDSVVIGLAPKAFNYEQLNEAFNVLL 132
            |::||:||.:.:|.:.:.|..::.:.|.:||....|.. .:::||||||:.||||.:||||.:.|
Frog    72 IFTSLTAARNLLEQKNVRPMLLVDDSALRDFEGVATHS-PNALVIGLAPQHFNYETMNEAFRLAL 135

  Fly   133 ENKNHKLIAVHQGKYYKRAEGLALGPGCFVKGLEFATGRTAKVIGKPNPYFFEGAL--AGRDPAS 195
            :..  .:||:|:.:|||:.:|||||||.||..||:||...|.|:|||...||..||  .|..||.
Frog   136 DGA--PIIAIHKARYYKKKDGLALGPGPFVTALEYATDTRATVVGKPEKTFFLEALRSTGCSPAE 198

  Fly   196 CVMIGDDANDDIVGAMSMGMQGILVKTGKYL--PDVKPSPPPTALLENFAEAVDWIIQ 251
            .||||||..||:.||.:.||.|||||||||.  .:.|..|.|..:.::|.:|||.|::
Frog   199 AVMIGDDCRDDVGGAQNAGMLGILVKTGKYRAGDEGKIDPAPYVVCDSFPQAVDHILK 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17294	NP_609219.1	HAD-SF-IIA-hyp3	3..251	CDD:162372	122/251 (49%)
		Hydrolase_6	7..98	CDD:290083	43/90 (48%)
		DUF843	<84..136	CDD:114536	20/51 (39%)
		Hydrolase_like	175..245	CDD:289983	36/73 (49%)
hdhd2	NP_001120092.1	HAD-SF-IIA-hyp3	7..257	CDD:162372	122/253 (48%)
		Hydrolase_6	10..>87	CDD:290083	41/76 (54%)
		Hydrolase_like	176..250	CDD:289983	36/73 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I8010
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H12667
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3434
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1088513at2759
OrthoFinder	1	1.000	-	-		FOG0002535
OrthoInspector	1	1.000	-	-		oto103334
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5514
SonicParanoid	1	1.000	-	-		X5124
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090