DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wdr82 and AT5G66240

DIOPT Version :9

Sequence 1:	NP_609217.1	Gene:	Wdr82 / 34153	FlyBaseID:	FBgn0032030	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_569031.1	Gene:	AT5G66240 / 836756	AraportID:	AT5G66240	Length:	331	Species:	Arabidopsis thaliana

Alignment Length:	314	Identity:	126/314 - (40%)
Similarity:	192/314 - (61%)	Gaps:	8/314 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKIKLIDSVVRSFKVAKIFRENTDKINAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRTVNSKK 65
            :.::|.:.:::|.:...:||:...:|::|||......:::.|:||.|.:||....|..:|:||||
plant    11 VSLELSEEIIQSMEPGAVFRDYNCRISSIDFHKTSTCMVTASDDDSIRLYDVASATCLKTINSKK 75

  Fly    66 YGVDLIHFTHANNTAIHSSTK-VDDTIRYLSLHDNKYLRYFPGHTKKVISLCISPVEDTFLSGSL 129
            |||||:.||....|.|:||.. .||::|.||||||||||||.||..:|:||.:....:.|:||||
plant    76 YGVDLVCFTSHPTTVIYSSRNGWDDSLRLLSLHDNKYLRYFKGHHDRVVSLSLCSGGECFISGSL 140

  Fly   130 DKTLRLWDLRSPNCQGLMHLSGRPIAAYDPEGLIFAAGVNSESIKLYDLRSFDKGPFVTFKLNQE 194
            |:|:.|||.|...||||:.:.|||.||||.:|||||..... .|:::|.|.::||||..|.:..:
plant   141 DRTVLLWDQRVEKCQGLLRVQGRPAAAYDDQGLIFAIAFGG-YIRMFDARMYEKGPFEIFSVGGD 204

  Fly   195 KECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTGYPNNKGIPIEASFSPDSQFIFSG 259
            .. :...:|||.||:.:|::|....|.::|:|.||.|.||:..|......::|:|||:..|:.||
plant   205 LS-EANVVKFSNDGRLMLLTTMDGFIHVLDSFRGTLLSTFSVKPVAGESTLDAAFSPEGMFVVSG 268

  Fly   260 STDGRVHIWNADTGNKV-SVLN-GDHPGPVQCVQFNPKYMMLASACTNMAFWLP 311
            |.||..|.|...:|.:| |.:. |..| ||  :::.|...|..:..:.:||.:|
plant   269 SGDGSTHAWGVRSGKQVHSWMGLGSEP-PV--IKWGPGSPMFVTGSSELAFVIP 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wdr82	NP_609217.1	WD40	17..302	CDD:238121	121/287 (42%)
		WD40 repeat	26..63	CDD:293791	12/36 (33%)
		WD40 repeat	69..107	CDD:293791	23/38 (61%)
		WD40 repeat	112..150	CDD:293791	18/37 (49%)
		WD40 repeat	155..192	CDD:293791	17/36 (47%)
		WD40 repeat	199..235	CDD:293791	14/35 (40%)
		WD40 repeat	243..280	CDD:293791	15/37 (41%)
		WD40 repeat	287..309	CDD:293791	4/21 (19%)
AT5G66240	NP_569031.1	WD40	3..>313	CDD:225201	123/306 (40%)
		WD40	27..312	CDD:295369	121/289 (42%)
		WD40 repeat	36..73	CDD:293791	12/36 (33%)
		WD40 repeat	79..118	CDD:293791	23/38 (61%)
		WD40 repeat	123..158	CDD:293791	17/34 (50%)
		WD40 repeat	164..200	CDD:293791	17/36 (47%)
		WD40 repeat	208..244	CDD:293791	14/35 (40%)
		WD40 repeat	253..290	CDD:293791	15/36 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	86	1.000	Domainoid score	I2800
eggNOG	1	0.900	-	-		E1_KOG1446
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H42951
Inparanoid	1	1.050	250	1.000	Inparanoid score	I1029
OMA	1	1.010	-	-		QHG54522
OrthoDB	1	1.010	-	-		D1146727at2759
OrthoFinder	1	1.000	-	-		FOG0002456
OrthoInspector	1	1.000	-	-		otm2833
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR19861
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1869
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.940