DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wdr82 and AT5G14530

DIOPT Version :9

Sequence 1:	NP_609217.1	Gene:	Wdr82 / 34153	FlyBaseID:	FBgn0032030	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_196957.1	Gene:	AT5G14530 / 831304	AraportID:	AT5G14530	Length:	330	Species:	Arabidopsis thaliana

Alignment Length:	316	Identity:	124/316 - (39%)
Similarity:	201/316 - (63%)	Gaps:	7/316 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KLIDSVVRSFKVAKIFRENTDKINAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRTVNSKKYGV 68
            :|.|.:||...:..:|.:...||:::.|....:.|::.||||.:.::|.....|.:....||:|.
plant     5 ELDDGLVRRMAMGAVFSDFGGKIHSVGFHRTDDLLVTSSEDDSLRLFDIANAKQLKITYHKKHGT 69

  Fly    69 DLIHFTHANNTAIHSS----TKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISPVEDTFLSGSL 129
            |.:.|||..::.|.||    ....:::||||::||:.||||.||..:|:|||:||:.|:|:||||
plant    70 DRVCFTHHPSSLICSSRYNLESTGESLRYLSMYDNRILRYFKGHKDRVVSLCMSPINDSFMSGSL 134

  Fly   130 DKTLRLWDLRSPNCQGLMHLSGRPIAAYDPEGLIFAAGVNSESIKLYDLRSFDKGPFVTFKLNQE 194
            |:::||||||...|||::||.|||..|||.:||:||..:...::||:|.|.:|||||.||.:..:
plant   135 DRSVRLWDLRVNACQGILHLRGRPAVAYDQQGLVFAIAMEGGAVKLFDSRCYDKGPFDTFLVGGD 199

  Fly   195 KECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTGYPNNKGIPIEASFSPDSQFIFSG 259
             ..:...:|||.|||::|::|..:.|.::||:.|.....|:..| ::|.||||:|:||.:::.||
plant   200 -TAEVNDIKFSNDGKSMLLTTTNNNIYVLDAYRGEKKCGFSLEP-SQGTPIEATFTPDGKYVLSG 262

  Fly   260 STDGRVHIWNADTGNKVSVLNGDHPGPVQCVQFNPKYMMLASACTNMAFWLPTSEE 315
            |.||.:|.||.:..::|:... ::.|.|.|:::.|:..|..:|.|.:.||:|...|
plant   263 SGDGTLHAWNIENPSEVARWE-NNIGVVSCLKWAPRRAMFVAASTVLTFWIPNDGE 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wdr82	NP_609217.1	WD40	17..302	CDD:238121	114/288 (40%)
		WD40 repeat	26..63	CDD:293791	9/36 (25%)
		WD40 repeat	69..107	CDD:293791	17/41 (41%)
		WD40 repeat	112..150	CDD:293791	23/37 (62%)
		WD40 repeat	155..192	CDD:293791	18/36 (50%)
		WD40 repeat	199..235	CDD:293791	12/35 (34%)
		WD40 repeat	243..280	CDD:293791	16/36 (44%)
		WD40 repeat	287..309	CDD:293791	6/21 (29%)
AT5G14530	NP_196957.1	WD40	18..306	CDD:421866	115/290 (40%)
		WD40 repeat	27..63	CDD:293791	9/35 (26%)
		WD40 repeat	69..112	CDD:293791	17/42 (40%)
		WD40 repeat	117..152	CDD:293791	22/34 (65%)
		WD40 repeat	158..196	CDD:293791	19/37 (51%)
		WD40 repeat	203..239	CDD:293791	12/35 (34%)
		WD40 repeat	247..279	CDD:293791	15/31 (48%)
		WD40 repeat	289..311	CDD:293791	6/21 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	86	1.000	Domainoid score	I2800
eggNOG	1	0.900	-	-		E1_KOG1446
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I1029
OMA	1	1.010	-	-		QHG54522
OrthoDB	1	1.010	-	-		D1146727at2759
OrthoFinder	1	1.000	-	-		FOG0002456
OrthoInspector	1	1.000	-	-		otm2833
orthoMCL	1	0.900	-	-		OOG6_102214
Panther	1	1.100	-	-	LDO	PTHR19861
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1869
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840