DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wdr82 and Wdr82

DIOPT Version :9

Sequence 1:	NP_609217.1	Gene:	Wdr82 / 34153	FlyBaseID:	FBgn0032030	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001258235.1	Gene:	Wdr82 / 686295	RGDID:	1584269	Length:	313	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	216/313 - (69%)
Similarity:	269/313 - (85%)	Gaps:	0/313 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IKLIDSVVRSFKVAKIFRENTDKINAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRTVNSKKYG 67
            :||.|||:|||:|||:||||:||||..||:||||.:||.|:||.||:|||::|...||:.|||||
  Rat     1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYG 65

  Fly    68 VDLIHFTHANNTAIHSSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISPVEDTFLSGSLDKT 132
            ||||.:|||.||.::||.|:||||||||||||||:||||||:|:|::|.:|||:|||:|||||||
  Rat    66 VDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKT 130

  Fly   133 LRLWDLRSPNCQGLMHLSGRPIAAYDPEGLIFAAGVNSESIKLYDLRSFDKGPFVTFKLNQEKEC 197
            :||||||||||||||||.|:|:.::||||||||||||||.:|||||||||||||.|||:..::.|
  Rat   131 IRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTC 195

  Fly   198 DWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTGYPNNKGIPIEASFSPDSQFIFSGSTD 262
            :|||||||.|||.||||||||.|||:|||.|..:.||.||.|:|.:.:||||:||||||..||.|
  Rat   196 EWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSED 260

  Fly   263 GRVHIWNADTGNKVSVLNGDHPGPVQCVQFNPKYMMLASACTNMAFWLPTSEE 315
            |::|:||.::|.||:||:|.|.||:.|:|||||:|..||||:||||||||.::
  Rat   261 GKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASACSNMAFWLPTIDD 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wdr82	NP_609217.1	WD40	17..302	CDD:238121	195/284 (69%)
		WD40 repeat	26..63	CDD:293791	21/36 (58%)
		WD40 repeat	69..107	CDD:293791	28/37 (76%)
		WD40 repeat	112..150	CDD:293791	30/37 (81%)
		WD40 repeat	155..192	CDD:293791	30/36 (83%)
		WD40 repeat	199..235	CDD:293791	26/35 (74%)
		WD40 repeat	243..280	CDD:293791	21/36 (58%)
		WD40 repeat	287..309	CDD:293791	14/21 (67%)
Wdr82	NP_001258235.1	WD40	15..300	CDD:238121	195/284 (69%)
		WD40 repeat	24..61	CDD:293791	21/36 (58%)
		WD40 repeat	67..105	CDD:293791	28/37 (76%)
		WD40 repeat	110..148	CDD:293791	30/37 (81%)
		WD40 repeat	153..190	CDD:293791	30/36 (83%)
		WD40 repeat	197..233	CDD:293791	26/35 (74%)
		WD40 repeat	241..282	CDD:293791	23/40 (58%)
		WD40 repeat	285..307	CDD:293791	14/21 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339338
Domainoid	1	1.000	156	1.000	Domainoid score	I4102
eggNOG	1	0.900	-	-		E1_KOG1446
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H42951
Inparanoid	1	1.050	464	1.000	Inparanoid score	I1485
OMA	1	1.010	-	-		QHG54522
OrthoDB	1	1.010	-	-		D1146727at2759
OrthoFinder	1	1.000	-	-		FOG0002456
OrthoInspector	1	1.000	-	-		oto97498
orthoMCL	1	0.900	-	-		OOG6_102214
Panther	1	1.100	-	-	LDO	PTHR19861
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1869
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.810