Protein Alignment CG7627 and Abcb8

DIOPT Version :9

• Sequence 1: NP_001245943.1
• Gene: CG7627 / 34148
• FlyBaseID: FBgn0032026
• Length: 1355
• Species: Drosophila melanogaster
• Sequence 2: NP_083296.2
• Gene: Abcb8 / 74610
• MGIID: 1351667
• Length: 717
• Species: Mus musculus
• Alignment Length: 540
• Identity: 134/540 - (24%)
• Similarity: 240/540 - (44%)
• Gaps: 100/540 - (18%)

  Fly   826 LVTVARSFLFFNLAMKASIRLHNSMFRGITRAAMYFFNTNPSGRILNRFSKDMGQVDEILPAVMM 890
            |:|.....|..::..:.::.:..::|..:.|..:.||:...:|::::|.:.|:.:.......|:.
Mouse   189 LLTFGYLVLLSHIGERMAMDMRKALFSSLLRQDIAFFDAKKTGQLVSRLTTDVQEFKSSFKLVIS 253

  Fly   891 DVIQIFLALAGIVIVIAVVNP-----LFLIPTVVLGI---IFYQLRTFYLKTSRDVKRMEAITRS 947
            ..::....:.|.::.:::::|     |.::...::|:   :...||    |.||..:  |.|.|:
Mouse   254 QGLRSCTQVIGSLVSLSMLSPRLTLMLAVVTPALMGVGTLMGSGLR----KLSRQCQ--EQIARA 312

  Fly   948 PVYSHLAASLTGLSTIRAFGAQRVLE----AEFDN--------------YQDMHSSAF------Y 988
            ...:..|  |..:.|:|||..::..|    ||.::              :|.:.:.||      .
Mouse   313 TGVADEA--LGNVRTVRAFAMEKREEERYQAELESCCCKAEELGRGIALFQGLSNIAFNCMVLGT 375

  Fly   989 MFISTSRAFGYWLDCFCVIYIAIITLSFFIFPPANGGDVGLAITQAMGMTGMVQWGMRQSAELE- 1052
            :||..|...|..|                     .|||:       |......|...|..|.|.
Mouse   376 LFIGGSLVAGQQL---------------------KGGDL-------MSFLVASQTVQRSMASLSV 412

  Fly  1053 ------NTMTAVERVVEYEDIEP----EGALEAPADKKPPKSWPEQGKIVFDELSLRYTPDPKSE 1107
                  ..::|..||.||..:.|    .|....|       :...:|.|.|..::..| |.....
Mouse   413 LFGQVVRGLSAGARVFEYMALSPVIPLTGGYCIP-------NKDIRGSITFQNVTFSY-PCRPGF 469

  Fly  1108 NVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRLSYND--GSVLIDKRDTSEMGLHDLRSK-I 1169
            ||||..:..:...:.|.:||::|.||:::.:.|.|. |:.  |||.:|..|...:....||.: |
Mouse   470 NVLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERF-YDPEAGSVTLDGHDLRTLNPSWLRGQVI 533

  Fly  1170 SIIPQEPVLFSGTMRYN-----LDPFDEYSDDKLWRSLEEVKLKEVVADLPSGLQSKITEGGTNF 1229
            ..|.||||||:.|:..|     ||.    ||::::.:..|....|.::..|.|..:.:.|.||..
Mouse   534 GFISQEPVLFATTIMENIRFGKLDA----SDEEVYTAAREANAHEFISSFPDGYSTVVGERGTTL 594

  Fly  1230 SVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQTTIRNKFKECTVLTIAHRLHTIMDSD 1294
            |.||:|.:.:|||::::..:|::||||:.:|.:::.::|..:.......|||.|||||.|:..:.
Mouse   595 SGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRAAH 659

  Fly  1295 KVLVMDAGRAVEFGTPYELL 1314
            .::||..|:..|.||..|||
Mouse   660 SIIVMANGQVCEAGTHEELL 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7627	NP_001245943.1	CFTR_protein	12..1315	CDD:273530	134/540 (25%)
		ABC_membrane	107..360	CDD:294371
		ABCC_MRP_domain1	445..645	CDD:213217
		ABC_membrane	815..1014	CDD:294371	40/219 (18%)
		ABCC_MRP_domain2	1089..1310	CDD:213211	74/228 (32%)
Abcb8	NP_083296.2	MdlB	116..695	CDD:224055	134/540 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	695..717

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000