Protein Alignment CG7627 and Tap2

DIOPT Version :9

• Sequence 1: NP_001245943.1
• Gene: CG7627 / 34148
• FlyBaseID: FBgn0032026
• Length: 1355
• Species: Drosophila melanogaster
• Sequence 2: NP_114445.2
• Gene: Tap2 / 24812
• RGDID: 3818
• Length: 703
• Species: Rattus norvegicus
• Alignment Length: 558
• Identity: 150/558 - (26%)
• Similarity: 264/558 - (47%)
• Gaps: 82/558 - (14%)

  Fly   790 EELEPRLSTWLRDI-GLSVDAEMLDTYIF--TVITVLTILVTVAR--SFLFFNLAMKASIRLHNS 849
            |.|.|..|..:.|| |...|.:...:.||  .:.:|.:.|....|  ||||  ...:.::|:...
  Rat   166 ETLIPHYSGRVIDILGGDFDPDAFASAIFFMCLFSVGSSLSAGCRGGSFLF--TMSRINLRIREQ 228

  Fly   850 MFRGITRAAMYFFNTNPSGRILNRFSKDMGQVDEILPAVMMDVIQIFLALAGIVIVIAVVNP--- 911
            :|..:.|..:.||....:|.:.:|.|.|...:...||.....:::..:.:.|:...:..|:|
  Rat   229 LFSSLLRQDLAFFQETKTGELNSRLSSDTSLMSRWLPFNANILLRSLVKVVGLYYFMLQVSPRLT 293

  Fly   912 ---LFLIP-TVVLGIIFYQLRTFYLKTSRD-VKRMEAITRSPVYSHLAASLTGLSTIRAFGAQRV 971
               |..:| |:....::.......||..:| |.:...:.|..|        .||.|:|:|||:
  Rat   294 FLSLLDLPLTIAAEKVYNPRHQAVLKEIQDVVAKAGQVVREAV--------GGLQTVRSFGAE-- 348

  Fly   972 LEAEFDNY-------------QDMHSSAFYMFISTSRAFGYW---LDC-FCVIYIAIIT----LS 1015
             |.|...|             :|:... .|:.|....|.|..   |:| ...|....:|    ||
  Rat   349 -EQEVSRYKEALERCRQLWWRRDLEKE-LYLVIRRVMALGMQVLILNCGVQQILAGEVTRGGLLS 411

  Fly  1016 FFIFPPANGGDVGLAITQAMGMTGMVQWGMRQSAELENTMTAVERVVEYEDIEPEGALEAPADKK 1080
            |.::..    :||..:...:.|.|          ::.:.:.|.|:|..|.|..|.  |..|....
  Rat   412 FLLYQE----EVGHHVRNLVYMYG----------DMLSNVGAAEKVFSYLDRRPN--LPKPGTLA 460

  Fly  1081 PPKSWPEQGKIVFDELSLRYTPDPKSENVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRLSY 1145
            ||:   .:|::.|.::|..| |....:.||:.|:|.:.|.:...:||..|:|||: :.||.:..|
  Rat   461 PPR---VEGRVEFQDVSFSY-PSRPEKPVLQGLTFTLHPGKVTALVGPNGSGKST-VAALLQNLY 520

  Fly  1146 --NDGSVLIDKRDTSEMGLHDLRSKISIIPQEPVLFSGTMRYNLDPFDEY-----SDDKLWRSLE 1203
              ..|.||:|.....:...|.|..::.::.||||||||:::.|:    .|     .|.::..:.:
  Rat   521 QPTGGKVLLDGEPLVQYDHHYLHRQVVLVGQEPVLFSGSVKDNI----AYGLRNCEDAQVMAAAQ 581

  Fly  1204 EVKLKEVVADLPSGLQSKITEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQ 1268
            .....:.:.::.:|:.::|.|.|:..:|||:|.:.:|||::|..|:|::||||:.:|.:.:..:|
  Rat   582 AACADDFIGEMTNGINTEIGERGSQLAVGQKQRLAIARALVRNPRVLILDEATSALDAECEQALQ 646

  Fly  1269 TTIRNKFKECTVLTIAHRLHTIMDSDKVLVMDAGRAVE 1306
            |. |:: ::.|:|.|||||||:.::|:|||:..|:.||
  Rat   647 TW-RSQ-EDRTMLVIAHRLHTVQNADQVLVLKQGQLVE 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7627	NP_001245943.1	CFTR_protein	12..1315	CDD:273530	150/558 (27%)
		ABC_membrane	107..360	CDD:294371
		ABCC_MRP_domain1	445..645	CDD:213217
		ABC_membrane	815..1014	CDD:294371	51/231 (22%)
		ABCC_MRP_domain2	1089..1310	CDD:213211	74/225 (33%)
Tap2	NP_114445.2	3a01208	1..697	CDD:273363	150/558 (27%)
		ABC_membrane	156..416	CDD:279056	62/263 (24%)
		P-loop_NTPase	457..680	CDD:304359	74/233 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000