| Sequence 1: | NP_001245943.1 | Gene: | CG7627 / 34148 | FlyBaseID: | FBgn0032026 | Length: | 1355 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001028508.2 | Gene: | Abcc4 / 239273 | MGIID: | 2443111 | Length: | 1325 | Species: | Mus musculus |
| Alignment Length: | 1359 | Identity: | 600/1359 - (44%) |
|---|---|---|---|
| Similarity: | 865/1359 - (63%) | Gaps: | 88/1359 - (6%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 8 DLPENPREHCNFISAACFWYTMPTFIKGRKRTLDTKDLYRALKEHKSETLGNKLCASWELEL--- 69
Fly 70 EKTKGKPNLLRALLRVFGWYFALLGLVLFLLELGLRTLQPIFLLKLIAYY----THGSESIESAY 130
Fly 131 YYAAGVILCSALNVIIMHPYMLGTMHVGLKMRVGMCSMIYRKALRLSKSALGDTTAGHVVNLMSN 195
Fly 196 DVGRLDLATIFVHYLWVGPLETLFITYLMYREIGIAAVFGVAFMLLFIPLQAYLGKRTSVLRLRT 260
Fly 261 ALRTDERVRMMNEIISGIQVIKMYAWELPFEHMVAFARKKEINAIRHVSYIRGILLSFIIFLTRV 325
Fly 326 SIFLSLVGYVLLGTFLTPEVAFLITAYYNILRTTMTVFFPQGISQMAETLVSIKRVQKYMQSDET 390
Fly 391 NVMDMSVDLTEDFQGSNQETVHADGDEERDEAEDKLLGPPIATVNENAKLSEAGISISGLMAKWD 455
Fly 456 --VNSPDYSLNGVNLRVQPGTMLGIVGRTGSGKSSLIQAILGELPAESGEIKVNGSMSYASQEPW 518
Fly 519 LFSGTVRQNILFGQPMDRRRYAKVVKKCALERDFELLPFKDKTIVGERGASLSGGQKARISLARA 583
Fly 584 VYRETSIYLLDDPLSAVDTHVARHLFEQCMRGYLRERIVILATHQLQFLQHADQIVIMDKGRVSA 648
Fly 649 VGTYESLRESGLDFASMLADPERDEQSEERSRS------RSGSYTHSHSDQRRNSEQSLLSMADS 707
Fly 708 CMDDLEAEQANNQERQEAGQIGLRLYSKYFKAGGGFFAFFVMMGFCVLSQGLASLGDYFLSYWVT 772
Fly 773 KKG--NVAYRADNNDTTRSEELEPRLSTWLRDIGLSVDAEMLDTYIFTVITVLTILVTVARSFLF 835
Fly 836 FNLAMKASIRLHNSMFRGITRAAMYFFNTNPSGRILNRFSKDMGQVDEILPAVMMDVIQIFLALA 900
Fly 901 GIVIVIAVVNPLFLIPTVVLGIIFYQLRTFYLKTSRDVKRMEAITRSPVYSHLAASLTGLSTIRA 965
Fly 966 FGAQRVLEAEFDNYQDMHSSAFYMFISTSRAFGYWLDCFCVIYIAIITL-SFFIFPPANGGDVGL 1029
Fly 1030 AITQAMGMTGMVQWGMRQSAELENTMTAVERVVEYEDIEPEGALEAPADKKPPKSWPEQGKIVFD 1094
Fly 1095 ELSLRYTPDPKSENVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRLSYNDGSVLIDKRDTSE 1159
Fly 1160 MGLHDLRSKISIIPQEPVLFSGTMRYNLDPFDEYSDDKLWRSLEEVKLKEVVADLPSGLQSKITE 1224
Fly 1225 GGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQTTIRNKFKECTVLTIAHRLHT 1289
Fly 1290 IMDSDKVLVMDAGRAVEFGTPYELLTLADSKVFHGMVKQTGHATYESLLKIAQKAFENR 1348 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG7627 | NP_001245943.1 | CFTR_protein | 12..1315 | CDD:273530 | 590/1320 (45%) |
| ABC_membrane | 107..360 | CDD:294371 | 112/256 (44%) | ||
| ABCC_MRP_domain1 | 445..645 | CDD:213217 | 106/201 (53%) | ||
| ABC_membrane | 815..1014 | CDD:294371 | 94/198 (47%) | ||
| ABCC_MRP_domain2 | 1089..1310 | CDD:213211 | 145/220 (66%) | ||
| Abcc4 | NP_001028508.2 | PLN03130 | 12..1284 | CDD:215595 | 596/1341 (44%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 657..690 | 5/32 (16%) | |||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:O15439 | 1322..1325 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167841677 | |
| Domainoid | 1 | 1.000 | 232 | 1.000 | Domainoid score | I2403 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0054 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H74563 | |
| Inparanoid | 1 | 1.050 | 1109 | 1.000 | Inparanoid score | I229 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG51855 | |
| OrthoDB | 1 | 1.010 | - | - | D138195at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001028 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42331 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100026 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24223 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5383 |
| SonicParanoid | 1 | 1.000 | - | - | X771 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 15 | 14.840 | |||||