Protein Alignment CG7627 and haf-8

DIOPT Version :9

• Sequence 1: NP_001245943.1
• Gene: CG7627 / 34148
• FlyBaseID: FBgn0032026
• Length: 1355
• Species: Drosophila melanogaster
• Sequence 2: NP_502776.1
• Gene: haf-8 / 190369
• WormBaseID: WBGene00001818
• Length: 633
• Species: Caenorhabditis elegans
• Alignment Length: 526
• Identity: 135/526 - (25%)
• Similarity: 242/526 - (46%)
• Gaps: 56/526 - (10%)

  Fly   833 FLFFNLAMKASIR-LHNSMFRGITRAAMYFFNTNPSGRILNRFSKDMGQVDEILPAVMMDVI-QI 895
            :.|...|.|.:.| :...:||.|....:.||:.|.:|::::|.:.|...:...||..:..:: .:
 Worm   116 YFFMQYAEKLTARNIRIQLFRSILHQEISFFDENKTGQLVSRITHDSESISNTLPVHIETLVNNL 180

  Fly   896 FLALAGIVIVIAVVNPLFLIPTVVLGIIFYQLRTFYL---KTSRDVKRMEAITRSPVYSHLAASL 957
            |:....|.|:......|.|...:...|.....|.:.|   |.|.......|.:...|...|:|
 Worm   181 FMFFGSIPIMFCYSWQLTLTSFIEFPITLLMTRYYGLAVEKLSEKENDATAASNETVEEVLSA-- 243

  Fly   958 TGLSTIRAFGAQRVLEAEF-DNYQDMHSSAFYMFISTSRA-----FGY-WLDCFCVIYIAIITLS 1015
              :.|:|:|.|:...:..: .|.:|      :..|||...     :.| |         |::..|
 Worm   244 --IRTVRSFAAENFEQKRYTKNTED------WFKISTKTVTLGTIYNYFW---------ALMLRS 291

  Fly  1016 FFIFPPANGGDVGLAITQAMGMTGMV-----QWGMRQS--------AELENTMTAVERVVEYEDI 1067
            ..:.....||  .||:...|....::     .|.:..:        :.:..|:....:|:...:.
 Worm   292 QDVIRYLYGG--YLALNGRMAPEALLTFIFYHWRLHTAINAFSSLFSGVMKTIGLSRKVIHLINR 354

  Fly  1068 EPEGALEAPADKKPPKSWPEQGKIVFDELSLRYTPDPKSENVLKSLSFVIKPKEKVGIVGRTGAG 1132
            :|:  |:.....:.|:.   ||||.|:.:...| |..|:.||:..::..|:..:.|.:||.:|.|
 Worm   355 KPQ--LDYDFGTETPEI---QGKIEFEVVEFAY-PTRKTVNVINGINLSIESGKTVALVGPSGNG 413

  Fly  1133 KSSLINALFRLSY--NDGSVLIDKRDTSEMGLHDLRSKISIIPQEPVLFSGTMRYN-LDPFDEYS 1194
            ||:|: :|.:..|  ..|.:|.|......:......|.|:::.|||.|||||:|.| |...:..:
 Worm   414 KSTLV-SLIQQFYTPQSGRILTDGIPIQNINHQHYHSNIALVAQEPTLFSGTIRENILFGIENGT 477

  Fly  1195 DDKLWRSLEEVKLKEVVADLPSGLQSKITEGGTNFSVGQRQLVCLARAILRENRILVMDEATANV 1259
            ::.:.::.|...:.|.|:.:..|..:|..|.|...|.||:|.:.:|||::|..|:|::||||:.:
 Worm   478 EEAMLKAAEMANVHEFVSKMDDGYDTKCGEKGVQMSGGQKQRIAIARALIRNPRVLILDEATSAL 542

  Fly  1260 DPQTDGLIQTTIRNKFKECTVLTIAHRLHTIMDSDKVLVMDAGRAVEFGTPYELLTLADSKVFHG 1324
            |.:::|::|..:....||.||:.|||||.|:..:.|:.|::.|...|.|...||:...|...:..
 Worm   543 DSESEGMVQEALNKCAKERTVIVIAHRLSTVRKAQKIAVIENGSVKEMGCHDELMENQDGLYYKL 607

  Fly  1325 MVKQTG 1330
            :.||.|
 Worm   608 VSKQLG 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7627	NP_001245943.1	CFTR_protein	12..1315	CDD:273530	131/509 (26%)
		ABC_membrane	107..360	CDD:294371
		ABCC_MRP_domain1	445..645	CDD:213217
		ABC_membrane	815..1014	CDD:294371	41/192 (21%)
		ABCC_MRP_domain2	1089..1310	CDD:213211	75/223 (34%)
haf-8	NP_502776.1	MdlB	42..613	CDD:224055	134/524 (26%)
		ABC_membrane	63..318	CDD:279056	47/222 (21%)
		ABC_MTABC3_MDL1_MDL2	373..611	CDD:213216	76/239 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000