Protein Alignment CG7627 and mrp-7

DIOPT Version :10

• Sequence 1: NP_609215.3
• Gene: CG7627 / 34148
• FlyBaseID: FBgn0032026
• Length: 1355
• Species: Drosophila melanogaster
• Sequence 2: NP_507812.3
• Gene: mrp-7 / 180289
• WormBaseID: WBGene00003413
• Length: 1525
• Species: Caenorhabditis elegans
• Alignment Length: 1409
• Identity: 481/1409 - (34%)
• Similarity: 735/1409 - (52%)
• Gaps: 179/1409 - (12%)

  Fly     3 SLKTADLPENPREHCNFISAACFWYTMPTFIKGRKRTLDTKDLYRALKEHKSETLGNKLCASWE- 66
            |.|:|..||   ...:|::....|:.......|.:|.|:..|::...:...:|.|.....:.||
 Worm   201 SSKSAASPE---LQSSFLNRLTLWWFNSIPWTGARRDLEIDDIFELNERSGTEFLSELWESFWEP 262

  Fly    67 -----------------LELEKTKGK-PNLLRALLRVFGWYFALLGLVLFLLELGLRTLQ---PI 110
                             .|.||.... |:::.:|..:|.|.|.|...:.|:.:    |:|   |.
 Worm   263 KRLKYIHDTSIWAKKDPSEQEKDPVVIPSVVSSLFMMFRWEFLLASTLKFVSD----TMQFASPF 323

  Fly   111 FLLKLIAYYTHGSESIESAYYY---AAGVIL--CSALNVIIMHPYMLGTMHVGLKMRVGMCSMIY 170
            .|.:|:.:.     |.::|.::   |..:::  .|.|..:|::.|......:|.|::..:.:.:|
 Worm   324 LLHELLNFI-----SAKNAPFWKGMALSILMFSVSELRSLILNGYFYIMFRMGTKIQTSLTAAVY 383

  Fly   171 RKALRLSKSALGDTTAGHVVNLMSNDVGRLDLATIFVHYLWVGPLETLFITYLMYREIGIAAVFG 235
            :|.|.:|.||..|.|.|.:||||:.||.|..:.|..:...|..|.:..|....::..:|.:|:.|
 Worm   384 KKTLLISNSARRDRTVGEIVNLMAIDVERFQMITPQIQQFWSCPYQITFALVYLFITLGYSALPG 448

  Fly   236 VAFMLLFIPLQAYLGKRTSVLRLRTALRTDERVRMMNEIISGIQVIKMYAWELPFEHMVAFARKK 300
            |..|::|:|:...........::......|||.:|:||:::||:|:|:||||:|.|..:...|.|
 Worm   449 VVIMVIFVPMNIISSMIVRKWQIEQMKLKDERTKMVNEVLNGIKVVKLYAWEVPMEAYIDEIRTK 513

  Fly   301 EINAIRHVSYIRGILLSFIIFLTRVSIFLSLVGYVLLGTF--------LTPEVAFLITAYYNILR 357
            |:..|:..:.:|.||.||    ...|.|  ||.....|||        |||::||:..|.:|.||
 Worm   514 ELALIKKSAMVRNILDSF----NTASPF--LVALFSFGTFVLSNPSHLLTPQIAFVSLALFNQLR 572

  Fly   358 TTMTVFFPQGISQMAETLVSIKRVQKYMQSDETN--VMDMSVDLTEDFQGSNQETVHADGDEERD 420
            :.||: ....|:|..:.:||.||:::::.::|.:  .:|.||
 Worm   573 SPMTM-IALLINQAVQAVVSNKRLKEFLVAEELDEKCVDRSV----------------------- 613

  Fly   421 EAEDKLLGPPIATVNENAKLSEAGISISGLMAKWDVN--SPDYSLNGVNLRVQPGTMLGIVGRTG 483
                            |.:.|...:.:..|.|.||..  :.:.:|..|:|.....:::.:||:.|
 Worm   614 ----------------NIERSHNAVRVENLTASWDPEEAAGEKTLQDVDLTAPRNSLIAVVGKVG 662

  Fly   484 SGKSSLIQAILGELPAESGEIKVNGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYAKVVKKCAL 548
            ||||||:||:|||:....|.|.|||.::|..|:||:.:.|:|.||.||:|.||:||.:|:..|||
 Worm   663 SGKSSLLQALLGEMGKLRGRIGVNGRVAYVPQQPWIQNMTLRDNITFGRPFDRKRYDQVLYACAL 727

  Fly   549 ERDFELLPFKDKTIVGERGASLSGGQKARISLARAVYRETSIYLLDDPLSAVDTHVARHLFEQCM 613
            :.|.::||..|:|.:||:|.:||||||||:|||||||:...:|||||||||||.||.||:||:.:
 Worm   728 KADIKILPAGDQTEIGEKGINLSGGQKARVSLARAVYQNLDVYLLDDPLSAVDAHVGRHIFEKVI 792

  Fly   614 --RGYLRERIVILATHQLQFLQHADQIVIMDKGRVSAVGTYESL-RESGLDFASMLADPERDEQS 675
              .|.|||:..||.||.|.:.:.||:|::|.:|::...||:|.| :..||.|..|.......:.|
 Worm   793 GPNGLLREKTRILVTHGLTYTKMADEILVMLEGKIEESGTFEHLIKRRGLFFDFMEEYKSGSDNS 857

  Fly   676 EERSRSRSGSY--THSHSDQRRNSEQSLLSMAD---------------SCMDDLE---------- 713
            .|...|:...:  .........|.|..:|::.:               |.|...|
 Worm   858 SEAGGSQDDDFEAIGGEIQDYMNPEDVVLTVTNDLDETIRTPELTTQISTMSSPEKPPTGTSPAA 922

  Fly   714 -AEQANNQERQEA---GQIGLRLYSKYFKAGGGFFAFFVMMGFCVLSQGLASLGDYFLSYWVTKK 774
             .|..|...::|.   |::.:..|..|.|| .|:......:||.::...|..|..::||.|
 Worm   923 ATESQNKLIKKEGIAQGKVEIATYQLYVKA-AGYLLSIAFIGFFIVYMTLQILRSFWLSAW---- 982

  Fly   775 GNVAYRADNNDTTRSEELEPRLSTWLRDIGLSVDAEMLDTYIFTVITVLTILVTVARSFLFFNLA 839
                  :|..|.. |....|....|  .:|:.......:|..|.|..:..:.|           .
 Worm   983 ------SDEYDPD-SPSAHPMAKGW--RLGVYGALGFSETACFFVALLALVFV-----------G 1027

  Fly   840 MKASIRLHNSMFRGITRAAMYFFNTNPSGRILNRFSKDMGQVDEILPAVMMDVIQIFLALAGIVI 904
            .:||..||..:...:.|:.|.|::|.|.||||||.:||:..:|.:||.....::...|.:|..:|
 Worm  1028 QRASKNLHGPLIHNLMRSPMSFYDTTPLGRILNRCAKDIETIDMMLPMNFRYLVMCVLQVAFTLI 1092

  Fly   905 VIAVVNPLFLIPTVVLGIIFYQLRTFYLKTSRDVKRMEAITRSPVYSHLAASLTGLSTIRAFGAQ 969
            ||.:..|||.:..:.|.:|:.....:|:.|||.:||:|::.|||:|||...::.|.::|||||..
 Worm  1093 VIIISTPLFAVVILPLALIYLIFLRYYVPTSRQLKRLESVHRSPIYSHFGETIQGAASIRAFGKV 1157

  Fly   970 RVLEAEFDNYQDMHSSAFYMFISTSRAFGYWLDCF--CVIY----IAIITLSF-FIFPPANGGDV 1027
            .....:.....|......|..:.::|.....|:..  |:|:    .|:::..| :|..|   |.:
 Worm  1158 DEFRQDSGRILDTFIRCRYSSLVSNRWLAVRLEFVGNCIIFFAALFAVLSKEFGWITSP---GVI 1219

  Fly  1028 GLAITQAMGMTGMVQWGMRQSAELENTMTAVERVVEYEDIEPEGALEAP---ADKKPPKSWPEQG 1089
            |::::.|:.:|.::.:.:||.:|:|..:.:||||.||.: .|.   |||   ..::|...||.:|
 Worm  1220 GVSVSYALNITEVLNFAVRQVSEIEANIVSVERVNEYTN-TPN---EAPWRIEGREPAPGWPSRG 1280

  Fly  1090 KIVFDELSLRYTPDPKSENVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFR-LSYNDGSVLID 1153
            .:.||..|.||...  .:.||..:|..:...||:||||||||||||...|||| :....|.::||
 Worm  1281 VVKFDGYSTRYREG--LDLVLHDISADVAAGEKIGIVGRTGAGKSSFALALFRMIEAAGGRIVID 1343

  Fly  1154 KRDTSEMGLHDLRSKISIIPQEPVLFSGTMRYNLDPFDEYSDDKLWRSLEEVKLKEVVADLPSGL 1218
            ..:.|::|||||||.|:||||:|||||||:|:|||||..||||::||:||...||...|.||.||
 Worm  1344 DVEVSQIGLHDLRSNITIIPQDPVLFSGTLRFNLDPFFTYSDDQIWRALELAHLKHFAAGLPDGL 1408

  Fly  1219 QSKITEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQTTIRNKFKECTVLTI 1283
            ..||:|.|.|.||||||||.||||:||..|:||:|||||.||..||.|||.|||.:||||||.||
 Worm  1409 LYKISEAGENLSVGQRQLVALARALLRHTRVLVLDEATAAVDVATDALIQETIREEFKECTVFTI 1473

  Fly  1284 AHRLHTIMDSDKVLVMDAGRAVEFGTPYELLTLAD-SKVFHGMV 1326
            ||||:||||.|:::|:|.|..:||.||..|  :|| :..|..||
 Worm  1474 AHRLNTIMDYDRIMVLDKGSILEFDTPDAL--MADKNSAFAKMV 1515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7627	NP_609215.3	PLN03130	13..1348	CDD:215595	476/1399 (34%)
mrp-7	NP_507812.3	MRP_assoc_pro	14..1518	CDD:188098	481/1409 (34%)