Protein Alignment CG7806 and YOR1

DIOPT Version :10

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_011797.3
• Gene: YOR1 / 853198
• SGDID: S000003513
• Length: 1477
• Species: Saccharomyces cerevisiae
• Alignment Length: 1527
• Identity: 413/1527 - (27%)
• Similarity: 700/1527 - (45%)
• Gaps: 297/1527 - (19%)

  Fly   180 VTLIPKGSA---VYSSLPRSGVSAREDEGLL---------SQRYTYFQFD----LNES------- 221
            |.|.||.||   :.:.:.:...|:.:|:.||         ::..||...|    :.||
Yeast    21 VVLSPKASASSDISTDVDKDTSSSWDDKSLLPTGEYIVDRNKPQTYLNSDDIEKVTESDIFPQKR 85

  Fly   222 -----------HLGHAQDE--------ANLGSRFLFHWVQPLILKGVAGKLRKIEDLFDLPDALN 267
                       .:....||        .|:.|...|.||.|::..|....::. .|||.:...::
Yeast    86 LFSFLHSKKIPEVPQTDDERKIYPLFHTNIISNMFFWWVLPILRVGYKRTIQP-NDLFKMDPRMS 149

  Fly   268 ITRLSE------------------KLHLALSQSQ----------SLWRALHRCFGVEFYLIGILR 304
            |..|.:                  |.|...::.:          ::.|||...|..::::..:..
Yeast   150 IETLYDDFEKNMIYYFEKTRKKYRKRHPEATEEEVMENAKLPKHTVLRALLFTFKKQYFMSIVFA 214

  Fly   305 LIADLSGFAGPLLLGGLLRQDHADPNQVYY---------YALGLFGSTLLSAVCATHFDWRMAMV 360
            ::|:.:....|::...|:  :..:...:::         ||:|......::.:...||.....:.
Yeast   215 ILANCTSGFNPMITKRLI--EFVEEKAIFHSMHVNKGIGYAIGACLMMFVNGLTFNHFFHTSQLT 277

  Fly   361 SMKMRVGVVNSIYRKALEARG-LKESKPD--LLNLMSTDTDRIVNSCISFH-FFWSIPFKLFTTL 421
            .::.:..:..:..:|...|.. .:...|:  :.:.::||..|| ...:||. |....|..|...:
Yeast   278 GVQAKSILTKAAMKKMFNASNYARHCFPNGKVTSFVTTDLARI-EFALSFQPFLAGFPAILAICI 341

  Fly   422 YLLYLQLGAAFLAGV----------IFAALLIPINRWLAKRIGIFSSGLMTAKDARLSATTETMQ 476
            .||.:.||...|.|:          :||..||     |..||   ::.:.|  |||::...|.:.
Yeast   342 VLLIVNLGPIALVGIGIFFGGFFISLFAFKLI-----LGFRI---AANIFT--DARVTMMREVLN 396

  Fly   477 GAKQIKINAWEDIFITKIRGLRQEELRFLSK----RKYLDAMCVYFWATTPVLMCLLTFGVSVLM 537
            ..|.||...|||.:...|:.:|.:|:..:.|    |.:|.||.:    :.|.:..|:||.....:
Yeast   397 NIKMIKYYTWEDAYEKNIQDIRTKEISKVRKMQLSRNFLIAMAM----SLPSIASLVTFLAMYKV 457

  Fly   538 -------GNPLIASTTYTSVALLYMLIGPLNAFPWVLNGLIEAWVSIKRVQQLMDVPNLDYSSYY 595
                   || :.||.:...|..|.|...|:     .:...|:..:.:.|:|.|::.|..|.:...
Yeast   458 NKGGRQPGN-IFASLSLFQVLSLQMFFLPI-----AIGTGIDMIIGLGRLQSLLEAPEDDPNQMI 516

  Fly   596 NPIMRGSGG---------------------SGAGDDAPLDA-----------------PKASVLQ 622
            .  |:.|.|                     :.|.::|..:|                 |.||..:
Yeast   517 E--MKPSPGFDPKLALKMTHCSFEWEDYELNDAIEEAKGEAKDEGKKNKKKRKDTWGKPSASTNK 579

  Fly   623 MK-CASFCHDSD--EQTSPTPFR-MKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGE 683
            .| ..:...|.|  |....|.|| .||:|.|||.|:.:.|.||:|.||||.|:|:..:::.|||:
Yeast   580 AKRLDNMLKDRDGPEDLEKTSFRGFKDLNFDIKKGEFIMITGPIGTGKSSLLNAMAGSMRKTDGK 644

  Fly   684 VCVQELTTGFGYVPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQIL-GGDLVGVGE 747
            |.|.......||    ||:|..::||||::|:.|:::.|..|:..|:|:.||.|| .||:..:||
Yeast   645 VEVNGDLLMCGY----PWIQNASVRDNIIFGSPFNKEKYDEVVRVCSLKADLDILPAGDMTEIGE 705

  Fly   748 NGRTLSGGQRARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCILRLLKHKTRIVVTRNIQ 812
            .|.||||||:||:.|||:||:.|.:||.|||||::|:.|.:||:..|:..:|.:||||:.|..:.
Yeast   706 RGITLSGGQKARINLARSVYKKKDIYLFDDVLSAVDSRVGKHIMDECLTGMLANKTRILATHQLS 770

  Fly   813 LFFHANQILQV-KDGQL---------LPSEYMTQSIELSL--DEDADDEQEPTV----------- 854
            |...|::::.: .|||:         ..::.:...::.|.  .|..|:|||..|
Yeast   771 LIERASRVIVLGTDGQVDIGTVDELKARNQTLINLLQFSSQNSEKEDEEQEAVVAGELGQLKYES 835

  Fly   855 --------RRRSVELS--------------NQYDKKSLDSLLLEELREYGHLSGNVFTCYWKAVT 897
                    ::::.|:|              :..::::::|:.|:..|||  :...|..  |..:.
Yeast   836 EVKELTELKKKATEMSQTANSGKIVADGHTSSKEERAVNSISLKIYREY--IKAAVGK--WGFIA 896

  Fly   898 SPLAFTVLLSVVLMQLTRNLSDAWLAYWVTETTLDPHKNDTSLDHILMRPTVGNETESGHTTKFY 962
            .||...:::......|   .|..||:||    |.:..||         ||           ..||
Yeast   897 LPLYAILVVGTTFCSL---FSSVWLSYW----TENKFKN---------RP-----------PSFY 934

  Fly   963 LS-----IFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNR 1022
            :.     :|.|....|...|:..|.     ||.|:.:::.:.:|:::....::.|.|.:||||||
Yeast   935 MGLYSFFVFAAFIFMNGQFTILCAM-----GIMASKWLNLRAVKRILHTPMSYIDTTPLGRILNR 994

  Fly  1023 FSSDTNTVDDSLPFILNILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHASRDI 1087
            |:.||:::|:.|...|.::.:|.|.:||...:.:..:||..:.|..::.|::.:...|:.:.|:|
Yeast   995 FTKDTDSLDNELTESLRLMTSQFANIVGVCVMCIVYLPWFAIAIPFLLVIFVLIADHYQSSGREI 1059

  Fly  1088 KRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRF--QRDFQV-KLEESIKAQLTQSAAQQWLALR 1149
            |||.:...|.:|.:..|.|.|:.||::.|:..||  :.||.: |:.|   |.......|:|:.:.
Yeast  1060 KRLEAVQRSFVYNNLNEVLGGMDTIKAYRSQERFLAKSDFLINKMNE---AGYLVVVLQRWVGIF 1121

  Fly  1150 LQLLG---TLLVGGAGLLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVER 1211
            |.::.   .|::    .|..:|.:...:...||:.::|.|.:.|.|..:|.|:.:||.::.:.||
Yeast  1122 LDMVAIAFALII----TLLCVTRAFPISAASVGVLLTYVLQLPGLLNTILRAMTQTENDMNSAER 1182

  Fly  1212 IDQY---LQLEEEQNASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERIGIV 1273
            :..|   |.||.... .....||..||:.|.:.|..|..:||..|...|:.:....::.|:|||.
Yeast  1183 LVTYATELPLEASYR-KPEMTPPESWPSMGEIIFENVDFAYRPGLPIVLKNLNLNIKSGEKIGIC 1246

  Fly  1274 GRTGAGKTSVLAALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPR 1338
            |||||||:::::||.|:..||.|:|.:|.|::..|.|..||.::.:|.|:|.||.||:|:||||.
Yeast  1247 GRTGAGKSTIMSALYRLNELTAGKILIDNVDISQLGLFDLRRKLAIIPQDPVLFRGTIRKNLDPF 1311

  Fly  1339 HGFYDSEIWHAIKNSAA--------ATLLVQQLGGLDGK---------VETCGNNLSAGQRQLLC 1386
            :...|.|:|.|:....|        ..|......|..||         ||..|:|.|.|:||||.
Yeast  1312 NERTDDELWDALVRGGAIAKDDLPEVKLQKPDENGTHGKMHKFHLDQAVEEEGSNFSLGERQLLA 1376

  Fly  1387 LARALLKNAKVVAIDEGTSNLDDESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGR 1451
            |.|||::.:|::.:||.||::|.|:|..||..:...|..||:|.|||||:.:...|||:||:.|.
Yeast  1377 LTRALVRQSKILILDEATSSVDYETDGKIQTRIVEEFGDCTILCIAHRLKTIVNYDRILVLEKGE 1441

  Fly  1452 ICEEGNPQSLASDSSTIFYGMLLAQDIDPGEF 1483
            :.|...|.:|.|...:||..|.....|...:|
Yeast  1442 VAEFDTPWTLFSQEDSIFRSMCSRSGIVENDF 1473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	410/1514 (27%)
YOR1	NP_011797.3	MRP_assoc_pro	92..1468	CDD:188098	396/1449 (27%)