Protein Alignment CG7806 and YBT1

DIOPT Version :9

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_013052.1
• Gene: YBT1 / 850678
• SGDID: S000003971
• Length: 1661
• Species: Saccharomyces cerevisiae
• Alignment Length: 1528
• Identity: 420/1528 - (27%)
• Similarity: 721/1528 - (47%)
• Gaps: 217/1528 - (14%)

  Fly   118 VVHSGFLL-TARQYGELSHRGSLLINVVWLTVVVLDAVWL-RTSRHFSW---WP---WSLATLVC 174
            ::||..|| ...:..|.:.:|::...|.|..:.::.::.| ..:::|.:   :|   ||::.:..
Yeast   151 IIHSFILLHYVNKNPEFTQQGTITGLVEWCALFIIVSLRLANVNQNFKFINKYPGNLWSVSFINY 215

  Fly   175 DLLFGVTLIPKGSAVYSSLPRSGVSAREDEGLLSQRYTYFQFDLN-------------------- 219
            ..|| :::|         ||...:........:|::|...|..:|
Yeast   216 LALF-ISMI---------LPFRSIFIHHINSPISRKYYISQISINLALFLLLFFARIRNNFAIIY 270

  Fly   220 --ESHLGHAQDEANLGSRFL-FHWVQPLILKGVAGKLR-KIEDLFDLPDALNITRLSEKLHLALS 280
              :|.:..:.:.....:.|: :.|:...:.|  |.|:. |::|::.|........:.:|....:.
Yeast   271 KTDSWITPSPEPVTSIAGFICWAWLDSFVWK--AHKVSIKVKDIWGLMMQDYSFFVVKKFRYFVD 333

  Fly   281 QSQSLWR--ALHRCFGVEFYLI--GILRLIADLSGFAGPLLLGGLLR----QDHADPNQVYYYAL 337
            ......|  :|:..|....||:  .....:..:..|...:||..:|.    |..|..|..::|..
Yeast   334 HKVKRKRIFSLNLFFFFSNYLVLQCFWAFLGSVLSFIPTVLLKRILEYVEDQSSAPSNLAWFYVT 398

  Fly   338 GLFGSTLLSAVC---ATHFDWRMAMVSMKMRVGVVNSIYRKALEAR-GLKESKPD---------- 388
            .:|...:|.|:|   |..|..|   |.::|:..:::.||.|||..: ...::||.
Yeast   399 VMFVGRILVAICQAQALFFGRR---VCIRMKSIIISEIYTKALRRKISTNKTKPSNEDPQEINDQ 460

  Fly   389 -----------------LLNLMSTDTDRIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGV 436
                             ::|||:.|..::...|...|.|..........|.|||..||.|.:.||
Yeast   461 KSINGDEESTSSANLGAIINLMAIDAFKVSEICGYLHSFLEAFVMTVVALALLYRLLGFAAIVGV 525

  Fly   437 IFAALLIPINRWLAKRIGIFSSGLMTAKDARLSATTETMQGAKQIKINAWEDIFITKIRGLRQEE 501
            :....::|:|..|||.||......:...|.|:....|..|..:.||..:||:.|...|..:|:.|
Yeast   526 LIIVAMLPLNYKLAKYIGDLQKKNLAVTDNRIQKLNEAFQAIRIIKYFSWEENFEKDINTIRENE 590

  Fly   502 LRFLSKRKYLDAMCVYFWATTPVLMCLLTFGVSV-LMGNPLIASTTYTSVALLYMLIGPLNAFPW 565
            |..|..|..:.::..:.|..||.::...:|...: :.|..|.....:|:::|..:|..||:....
Yeast   591 LSLLLMRSIVWSISSFLWFVTPTIVTAASFAYYIYVQGEVLTTPVAFTALSLFTLLRDPLDRLSD 655

  Fly   566 VLNGLIEAWVSIKRVQQLMDVPNLDYSSYYNPIMRGSGGSGAGDDAPLDAPKASVLQMKCASFCH 630
            :|:.::::.||:.|||..::  ..|...|              |...:| |..:....:.::...
Yeast   656 MLSFVVQSKVSLDRVQDFLN--ENDTKKY--------------DQLTID-PNGNRFAFENSTISW 703

  Fly   631 DSDEQTSPTPFRMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCV------QEL 689
            |.|.|    .|::||:|::.|.|:|..:.||.|.||:|.|.|::..:...:|:|.|      |||
Yeast   704 DKDNQ----DFKLKDLNIEFKTGKLNVVIGPTGSGKTSLLMALLGEMYLLNGKVVVPALEPRQEL 764

  Fly   690 -------TTGFGYVPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQIL-GGDLVGVG 746
                   |....|..|:.||...|:::||::.:.|:|..||.|:.||.|:.|.:|| .|||..:|
Yeast   765 IVDANGTTNSIAYCSQAAWLLNDTVKNNILFNSPFNEARYKAVVEACGLKRDFEILKAGDLTEIG 829

  Fly   747 ENGRTLSGGQRARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCIL-RLLKHKTRIVVTRN 810
            |.|.||||||:.||:||||:|.:.:..||||.||::|:|.|..|..:||. .|::.:|.|:|:.|
Yeast   830 EKGITLSGGQKQRVSLARALYSNARHVLLDDCLSAVDSHTASWIYDNCITGPLMEDRTCILVSHN 894

  Fly   811 IQLFF-HANQILQVKDG--------------------QLLPSEYMTQ---SIELSLDEDADDEQE 851
            |.|.. :|..::.::||                    :|:.|..:::   |..|:..........
Yeast   895 IALTLRNAELVVLLEDGRVKDQGDPIDMLQKGLFGEDELVKSSILSRANSSANLAAKSSTSLSNL 959

  Fly   852 PTVRRRSVELSN---QYDKKSLD-------------SLLLEELREYGHLSGNVFTCY------WK 894
            |.|:.:.|.::|   .::.|.|.             .|:.||.:|.|.:..:|:..|      ||
Yeast   960 PAVKEQQVSVNNNSSHFEAKKLQKSLRTEAERTEDGKLIKEETKEEGVVGLDVYKWYLKIFGGWK 1024

  Fly   895 AVTSPLAFTVLLSVVLM-QLTRNLSDAWLAYWVTETTL-----------------DPHKNDTSLD 941
            .|      :.|.|:.|: ||.......|:..|.:...:                 ..|..|....
Yeast  1025 IV------SFLASLFLIAQLLYIGQSWWVRAWASHNVIAKIIPRAQRAIAFISKKASHLIDWRGS 1083

  Fly   942 HILMRPTVGNETESGHTTKFYLSIFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFA 1006
            ..:...:..|:..|||:|.:||.::..|..:.:|:...:..|...|||.|:..:...:|.||:.:
Yeast  1084 SQISMASAENQPSSGHSTMYYLVLYLIIGFAQALLGAGKTILNFVAGINASRKIFNMILNKVLHS 1148

  Fly  1007 KFNFFDITSVGRILNRFSSDTNTVDDSL-PFILNILLAQLAGLVGALCVSLYAMPWLGLVIIPMV 1070
            |..|||.|..|||:||||.|...:|..| |:|.....:.:..|...:.::.....:|.:.|:..:
Yeast  1149 KIRFFDATPTGRIMNRFSKDIEAIDQELTPYIQGAFYSLIECLSTVILITFITPQFLSVAIVVSI 1213

  Fly  1071 PIYLSLQQRYRHASRDIKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKA 1135
             :|..:...|...||::||..|.:.||:|.||:|||.|:||||:.....||.::...|::|:.|.
Yeast  1214 -LYYFVGYFYMAGSRELKRFESISRSPIYQHFSETLVGVTTIRAFGDEGRFMQENLHKIDENNKP 1277

  Fly  1136 QLTQSAAQQWLALRLQLLGTLLVGGAGLLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVA 1200
            ......|.:|||.|:.::|:|::.||||......:: .:.|:.|:.::||:|.|.....|:...:
Yeast  1278 FFYLWVANRWLAFRIDMIGSLVIFGAGLFILFNINN-LDSGMAGISLTYAISFTEGALWLVRLYS 1341

  Fly  1201 ETEQELVAVERIDQYLQLEEEQNASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTE 1265
            |.|..:.:|||:.:|:::|:|........||..||..|.:...::.|.|..:|...::.::|..:
Yeast  1342 EVEMNMNSVERVKEYMEIEQEPYNEHKEIPPPQWPQDGKIEVNDLSLRYAPNLPRVIKNVSFSVD 1406

  Fly  1266 AFERIGIVGRTGAGKTSVLAALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGT 1330
            |..:|||||||||||::::.||.|......|.|::|.:::..:.|..||..|.:|.|:|.||.||
Yeast  1407 AQSKIGIVGRTGAGKSTIITALFRFLEPETGHIKIDNIDISGVDLQRLRRSITIIPQDPTLFSGT 1471

  Fly  1331 VRENLDPRHGFYDSEIWHAIK-------------------NSAAATLL--VQQLGGLDGKVETCG 1374
            ::.||||...|.|.:|:.|:|                   |.|::|..  |.:...|..::...|
Yeast  1472 IKTNLDPYDEFSDRQIFEALKRVNLISEEQLQQGATRETSNEASSTNSENVNKFLDLSSEISEGG 1536

  Fly  1375 NNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDDESDLSIQQALRNAFKSCTLLFIAHRLRGLH 1439
            :|||.|||||:||||:||::.|::.:||.|:::|..||..||:.:|..|:..|:|.||||||.:.
Yeast  1537 SNLSQGQRQLMCLARSLLRSPKIILLDEATASIDYSSDAKIQETIRKEFQGSTILTIAHRLRSVI 1601

  Fly  1440 AMDRIIVLDDGRICEEGNPQSLASDSSTIFYGM 1472
            ..|:|:|:|.|.:.|..:|.||..:..:.||.|
Yeast  1602 DYDKILVMDAGEVKEYDHPYSLLLNKQSAFYSM 1634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	419/1526 (27%)
		ABC_membrane	328..560	CDD:294371	65/263 (25%)
		ABCC_MRP_domain1	621..827	CDD:213217	84/241 (35%)
		ABC_membrane	948..1192	CDD:279056	79/244 (32%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	88/240 (37%)
YBT1	NP_013052.1	MRP_assoc_pro	<353..1639	CDD:188098	385/1314 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2300
OMA	1	1.010	-	-		QHG53842
OrthoFinder	1	1.000	-	-		FOG0000087
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100026
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.670