DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7806 and ABCC13

DIOPT Version :9

Sequence 1:	NP_609207.1	Gene:	CG7806 / 34140	FlyBaseID:	FBgn0032018	Length:	1487	Species:	Drosophila melanogaster
Sequence 2:	NP_001323940.1	Gene:	ABCC13 / 815414	AraportID:	AT2G07680	Length:	1426	Species:	Arabidopsis thaliana

Alignment Length:	1398	Identity:	485/1398 - (34%)
Similarity:	756/1398 - (54%)	Gaps:	137/1398 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 VVWLTVVV-----LDAVWLRTSRHFSWWPW------------------SLATLVCDLLFGVTL-- 182
            |:|:.|::     ..|..:.||:...:| |                  .:..::.|:.||:::
plant    99 VMWIAVILSLKFACCACHVFTSQILCFW-WIFRFLTDALHLNMIFTLQEICLIMLDIAFGISINV 162

  Fly   183 --IPKGSAVYSSLPRSGVSAREDEGLLSQRYTYFQFDLNESHLGHAQDEANLGSRFLFHWVQPLI 245
              |.:.......|....:...:|:..:.:..::  :||                 |.|.::..::
plant   163 LRIKQAHPKIIPLEDPLIEDDDDQKRIEKNGSW--WDL-----------------FTFGYIGSIM 208

  Fly   246 LKGVAGKLRKIEDLFDLPDALNITRLSEKLHLALSQSQS---------LWRALHRCFGVEFYLIG 301
            ..|...:| ::|:|..||..::.....|.| |...|.|.         :| :::..:|..::.:|
plant   209 KHGSVKQL-ELENLLTLPPEMDPFTCCENL-LRCWQLQECNNYSTPSLIW-SIYGVYGWPYFRLG 270

  Fly   302 ILRLIADLSGFAGPLLLGGLLR--QDHADPNQVYYYALGLFGSTLLSAVCATHFDWRMAMVSMKM 364
            :|::..|..||||||||..|::  :..:..:..|..|:.|...::..:...|.:.:|::.:.:|:
plant   271 LLKVFNDCIGFAGPLLLNRLIKYLEKGSGSSVGYTLAISLGFISIFKSFLDTQYTFRLSKLKLKL 335

  Fly   365 RVGVVNSIYRKAL-----EARGLKESKPDLLNLMSTDTDRIVNSCISFHFFWSIPFKLFTTLYLL 424
            |..:::.||||.|     ...|..|.  ::...||.|.|||||.|.|.|..||:|.::...||||
plant   336 RSSIMSVIYRKCLWVNTANRSGFSEG--EIQTFMSVDADRIVNLCNSLHDLWSLPLQIGIALYLL 398

  Fly   425 YLQLGAAFLAGVIFAALLIPINRWLAKRIGIFSSGLMTAKDARLSATTETMQGAKQIKINAWEDI 489
            |.|:..|||:|:....||||:|:|::..|...:..:|..||.|:..|.|.:...:.:|:..|::.
plant   399 YTQVKFAFLSGLAITILLIPVNKWISVLIASATEKMMKLKDERIRKTGELLTNIRTLKMYGWDNW 463

  Fly   490 FITKIRGLRQEELRFLSKRKYLDAMCVYFWATTPVLMCLLTFGVSVLMGNPLIASTTYTSVALLY 554
            |...::..|..|:..|:.||||||.||:||||||.|..|.|||:..|||:.|.|:|.:|.:||..
plant   464 FADWLKETRATEVTHLATRKYLDAWCVFFWATTPTLFSLCTFGLFALMGHQLDAATVFTCLALFN 528

  Fly   555 MLIGPLNAFPWVLNGLIEAWVSIKRVQQLMDVPNLDYSSYYNPIMRGSGGSG-AGDDAPLDAPKA 618
            .||.|||:||||:||||:|::|.:||.:.:..  |::|..:      |..|| ..:|..:....|
plant   529 SLISPLNSFPWVINGLIDAFISTRRVSKFLCC--LEHSRDF------SIDSGFTSEDLAVCVEDA 585

  Fly   619 SVLQMKCASFCHDSDEQTSPTPFRMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGE 683
            |         |..|..........:|.:::.:..|..|.:.|.||.||:|.|::::..::|..|.
plant   586 S---------CTWSSNVEEDYNLTIKQVSLRVPKGSFVAVIGEVGSGKTSLLNSLLGEMRCVHGS 641

  Fly   684 VCVQELTTGFGYVPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQIL-GGDLVGVGE 747
            :.   |.....||||.|||..||:|:||::|..||.:.|...|.||||:.|:.:: |||:..:|:
plant   642 IL---LNGSVAYVPQVPWLLSGTVRENILFGKPFDSKRYFETLSACALDVDISLMVGGDMACIGD 703

  Fly   748 NGRTLSGGQRARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCIL-RLLKHKTRIVVTRNI 811
            .|..||||||||.|||||||....:||||||||::|:.|...|::..:| .||..|||::.|.||
plant   704 KGLNLSGGQRARFALARAVYHGSDMYLLDDVLSAVDSQVGCWILQRALLGPLLNKKTRVMCTHNI 768

  Fly   812 QLFFHANQILQVKDGQL--------LPSEYMTQSIELSLDEDADDEQEPTVRRRSVELS----NQ 864
            |....|:.|:.:..|::        :|.. ::.:..|:.:.|.......|.|:.::.:.    ::
plant   769 QAISCADMIVVMDKGKVNWSGSVTDMPKS-ISPTFSLTNEFDMSSPNHLTKRKETLSIKEDGVDE 832

  Fly   865 YDKKSLDSLLLEELREYGHLSGNVFTCYWKAVTSP--LAFTVLLSVVLMQLTRNLSDAWLAYWVT 927
            ..:.:.|.:.|||.:| |.:...|:..|  ||.|.  :...:|:|.||||.:||.:|.||:|||.
plant   833 ISEAAADIVKLEERKE-GRVEMMVYRNY--AVFSGWFITIVILVSAVLMQGSRNGNDLWLSYWVD 894

  Fly   928 ETTLDPHKNDTSLDHILMRPTVGNETESGHTTKFYLSIFTAIAVSNSLVTLARAFLFAYAGIKAA 992
            :|                     .:..|.::|.|||.:.....:.||::||.|||.||:.|:|||
plant   895 KT---------------------GKGVSHYSTSFYLMVLCIFCIINSILTLVRAFSFAFGGLKAA 938

  Fly   993 IFMHEKLLKKVMFAKFNFFDITSVGRILNRFSSDTNTVDDSLPFILNILLAQLAGLVGALCVSLY 1057
            :.:|..|:.|::.|...|||.|..||||||||||..|:|||||||||||||...||:|.:.|..|
plant   939 VHVHNALISKLINAPTQFFDQTPSGRILNRFSSDLYTIDDSLPFILNILLANFVGLLGIIVVLSY 1003

  Fly  1058 AMPWLGLVIIPMVPIYLSLQQRYRHASRDIKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRFQ 1122
            ......|:::|...||..||..||..||:::||.|.:.||:|..|||||.|.:|||:.::...|.
plant  1004 VQVLFLLLLLPFWYIYSKLQVFYRSTSRELRRLDSVSRSPIYASFTETLDGSSTIRAFKSEEHFV 1068

  Fly  1123 RDFQVKLEESIKAQLTQSAAQQWLALRLQLLGTLLVGGAGLLAAITASHT-----TNPGLVGLCI 1182
            ..|...|....:...::..|..||:|||||||:::|....::|.:.:...     ..||||||.:
plant  1069 GRFIEHLTLYQRTSYSEIIASLWLSLRLQLLGSMIVLFVAVMAVLGSGGNFPISFGTPGLVGLAL 1133

  Fly  1183 SYALSITGQLGDLLHAVAETEQELVAVERIDQYLQLEEEQNASGSAEPPFGWPTQGVLSFREVQL 1247
            |||..:...||.||.:..|||:|:|:|||:.||:.:.:|: .||.......||..|::.|..|.:
plant  1134 SYAAPLVSLLGSLLTSFTETEKEMVSVERVLQYMDVPQEE-VSGPQSLSDKWPVHGLVEFHNVTM 1197

  Fly  1248 SYREHLAPALRGITFQTEAFERIGIVGRTGAGKTSVLAALLRVAPLTHGEIRLDQVNLKTLPLSV 1312
            .|...|.|||..|:|..:....:|::|||||||:|:|.||.|:.|:..|||.:|..|:..||:..
plant  1198 RYISTLPPALTQISFTIQGGMHVGVIGRTGAGKSSILNALFRLTPVCSGEILVDGKNISHLPIRE 1262

  Fly  1313 LRERIGVITQEPFLFEGTVRENLDPRHGFYDSEIWHAIKNSAAATLLVQQLGGLDGKVETCGNNL 1377
            ||..:.|:.|.||||:|::|:||||.....|..||. |.:.......|:.:||||..|:..|.:.
plant  1263 LRSCLAVVPQSPFLFQGSLRDNLDPLGLSEDWRIWE-ILDKCKVKAAVESVGGLDSYVKESGCSF 1326

  Fly  1378 SAGQRQLLCLARALLKNAKVVAIDEGTSNLDDESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMD 1442
            |.||||||||||||||::|::.:||.|:|:|..:...:...:.:..|..|::.||||:..:..:|
plant  1327 SVGQRQLLCLARALLKSSKILCLDECTANIDVHTASLLHNTISSECKGVTVITIAHRISTVVDLD 1391

  Fly  1443 RIIVLDDGRICEEGNPQSLASDSSTIFYGMLLA 1475
            .|::||.|.:.|:|.||.|..|.|:.|...:.|
plant  1392 SILILDRGILVEQGKPQHLLQDDSSTFSSFVRA 1424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	484/1393 (35%)
		ABC_membrane	328..560	CDD:294371	87/236 (37%)
		ABCC_MRP_domain1	621..827	CDD:213217	80/207 (39%)
		ABC_membrane	948..1192	CDD:279056	104/248 (42%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	90/219 (41%)
ABCC13	NP_001323940.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	178	1.000	Domainoid score	I1074
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H58616
Inparanoid	1	1.050	761	1.000	Inparanoid score	I102
OMA	1	1.010	-	-		QHG53842
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	1	1.000	-	-		FOG0000087
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100026
Panther	1	1.100	-	-	LDO	PTHR24223
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5384
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840