Protein Alignment CG7806 and abcc6a

DIOPT Version :9

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: XP_009300481.1
• Gene: abcc6a / 566555
• ZFINID: ZDB-GENE-050517-18
• Length: 1507
• Species: Danio rerio
• Alignment Length: 1621
• Identity: 458/1621 - (28%)
• Similarity: 737/1621 - (45%)
• Gaps: 291/1621 - (17%)

  Fly     9 DFAWNWTQFCPTGLKPFANETNDLLPCFQEILL------QLPVYTLFAAISAYNFGNQSRHVVRN 67
            |..|:|.|...|.....:|       |||..:|      .|.|.:.|..:..|..|       |.
Zfish    11 DPLWDWNQTWYTHRPELSN-------CFQNTVLVWAPCIYLWVLSPFYCLHLYCHG-------RG 61

  Fly    68 GLQLRML-SIRTFLAMVLALLPVAKVFAFHQQGVELFAADLLVVSAECIMWVVHSGFLLTARQYG 131
            .|.|..| :.:..|...||      .|.|    ||.|                   ::|..|:..
Zfish    62 RLPLSSLCNAKLLLGFFLA------SFGF----VEFF-------------------YILLERRLE 97

  Fly   132 ELSHRGSLLINVV-WLTVVVLDAV--WLRT----SRHFSWWPWSLATLVCDLLFGVTLIPKGSAV 189
            ...|...||..:: .||||:...|  |.|.    |..|.::.|.|..| |      ::||..:.|
Zfish    98 IHQHLVFLLSPIMRSLTVVLAVCVIHWERVRGCRSSVFLFFFWLLGVL-C------SIIPLHAKV 155

  Fly   190 YSSLPRSGVSAREDEGLLSQ--RY----TYFQFDLNESHLGHAQDEANLG--------------- 233
            ..::         ::||...  ||    :||...|.:..|....|:|.||
Zfish   156 QLAV---------EQGLSPDIVRYLAFFSYFALQLAQLFLSCFADQAPLGKAVHKNACPVQDASF 211

  Fly   234 -SRFLFHWVQPLILKGVAGKL---------------RKIEDLFD--------------------- 261
             |:.||.|...||.||....|               |.|.||.:
Zfish   212 LSKILFWWFSGLIFKGYRSPLQAEDLWSLREEDTSERIISDLEEEWTAKRTKLQQQENHMSTSAA 276

  Fly   262 ----LPDALNITRLSEKLHLALSQSQSLWRALHRCFGVEFYLIGILRLIA-DLSGFAGPLLLG-- 319
                |||...:.|   |:....|....|.|.|.|.|| .::|.|.|.||. |:..|:.|.:|.
Zfish   277 LGSRLPDQAQLLR---KIQKEQSSGFCLLRTLARSFG-PYFLTGTLCLIVHDVFMFSVPQVLSLL 337

  Fly   320 -GLLRQDHADPNQVYYYALGLFGSTLLSAVCATHFDWRMAMVSMKMRVGVVNSIYRKALEARGLK 383
             |.::.:.....:.|:||..:|..:.|.:|....:.:....|.|:::..|:..:|||:|......
Zfish   338 LGFMKDEDTPLWKGYFYATLMFLLSCLQSVFNHQYTYTCFTVGMRVKTAVMGLVYRKSLVMNSSA 402

  Fly   384 E---SKPDLLNLMSTDTDRIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPI 445
            .   :..:::||:|.||.::::..:.|:..|..|.::...|:.|:..||.:.|||:.....:.|:
Zfish   403 RRTCTVGEIVNLVSADTQKLMDFVVYFNAVWLAPIEVTLCLFFLWQHLGPSALAGIATVIFIFPL 467

  Fly   446 NRWLAKRIGIFSSGLMTAKDARLSATTETMQGAKQIKINAWEDIFITKIRGLRQEELRFLSKRKY 510
            |.::|::........|...|.|:....|.:.|.|.:|..|||..|:.::.|.|::||:.|.|.:.
Zfish   468 NGFIARKRSKLQEIQMKYMDGRVKLMNEILNGIKILKFYAWEKAFLEQVLGYREKELKTLKKSQI 532

  Fly   511 LDAMCVYFWATTPVLMCLLTFGVSVLMG--NPLIASTTYTSVALLYMLIGPLNAFPWVLNGLIEA 573
            |.::.:..:.::..|:....|||.||:.  |.|.|...:.|:||:.:|..||:..|:.::..::|
Zfish   533 LYSVSLASFNSSSFLIAFAMFGVYVLIDDKNVLDAQKIFVSMALINILKTPLSQLPFAMSTTMQA 597

  Fly   574 WVSIKRVQQLM--------DVPNLDYSSYYNPIMRGSGGSGAGDDAPLDAPKASVLQMKCASFCH 630
            .||:||:.:.:        :|....:.|..:.::..:|......|.|           .|
Zfish   598 LVSLKRLGKFLCQDELKPDNVARESFKSDVDGVVFDNGTFSWSKDGP-----------PC----- 646

  Fly   631 DSDEQTSPTPFRMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCVQELTTGFGY 695
                        :|.|:|.:..|.||.:.|.||.||||.|||::...:...|.|.|:   ....|
Zfish   647 ------------LKRISVKVPCGSLVAVVGHVGSGKSSLLSAMLGETEKRSGTVSVK---GSIAY 696

  Fly   696 VPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQIL-GGDLVGVGENGRTLSGGQRAR 759
            |||..|:|..:::|||::|.:..|.||:.||.||||..||..| .||...:||.|..|||||:.|
Zfish   697 VPQQAWIQNASLQDNILFGREKKESWYQRVLEACALLPDLDNLPAGDATEIGEKGLNLSGGQKQR 761

  Fly   760 VALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCI--LRLLKHKTRIVVTRNIQLFFHANQILQ 822
            |:||||||:...||||||.||::||||.:||....|  ..:|:.|||::||..:.....|:.||.
Zfish   762 VSLARAVYRKGDVYLLDDPLSAVDAHVGQHIFNKVIGPKGILRDKTRVLVTHGMSFLPQADLILV 826

  Fly   823 VKDGQ----------------------------------------------LLPSEYMTQSIELS 841
            :.||:                                              |..::||..|.:||
Zfish   827 LVDGEISERGSYQELLNRNGAFADFIHTFANSERKECFSEALQRGSRKSVRLSVTDYMPFSRDLS 891

  Fly   842 LDE---------------DADDEQEPTVRRRSVELSNQYDKKSLDSLLLEELREYGHLSGNVFTC 891
            .::               |:|::..|               :.|..|...:....|.:...::..
Zfish   892 QEQLIGGDTNSIAIEPLPDSDEDHIP---------------EDLGKLTKVDKARIGRVKLEMYIE 941

  Fly   892 YWKAVTSPLAFTVLLSVVLMQLTRNLSDAWLAYWVTETTLDPHKNDTSLDHILMRPTVGNETESG 956
            |::.:..||..:::......|.....::.||:.|..:    |..|.|.|:
Zfish   942 YFRTIGLPLIISIVFLYAFQQAASLSNNYWLSLWADQ----PVINGTQLN--------------- 987

  Fly   957 HTTKFYLSIFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILN 1021
              |...|.::.|:..:..:.........:...|.|:..:|..||..|:.:..:||:.|..|.:||
Zfish   988 --TDLKLGVYGALGFAQGISIFGTTVAISLGCIIASRHLHLDLLNNVLHSPMSFFESTPSGNLLN 1050

  Fly  1022 RFSSDTNTVDDSLPFILNILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHASRD 1086
            ||:.:.:.:|:.:|..|.::|:....|.....:.|.|.|:..::|:|||.:|..:|..|...|..
Zfish  1051 RFAKEIDAIDNMIPDGLKMMLSYFFKLTEVCIIVLMATPFAAVIILPMVFLYGFIQSFYVATSCQ 1115

  Fly  1087 IKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAAQQWLALRLQ 1151
            ::||.|.:.||:|||..||:||.:.||:.....||......|::.:..|...:..|.:||.:.|:
Zfish  1116 LRRLESVSRSPIYTHLNETVQGASVIRAFNEQSRFIMGANHKVDHNQTAYFPRFIATRWLGVNLE 1180

  Fly  1152 LLGTLLVGGAGLLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERIDQYL 1216
            .||..:|..|.:| ::.|..|.:||:|||.:|::|.:||.|..::.:..:.|..:|:|||:.:|.
Zfish  1181 FLGNGIVLAASIL-SVMAKGTLSPGMVGLAVSHSLQVTGFLSWIVRSWTDVENNIVSVERVKEYA 1244

  Fly  1217 QLEEEQ--NASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERIGIVGRTGAG 1279
            ...:|.  :..||:.|| .||..|.:.|::..|.||:.|..||:||:......|:||||||||||
Zfish  1245 DTPKEAAWSIEGSSLPP-SWPQTGTIEFQDYGLQYRKGLELALKGISVHIHEREKIGIVGRTGAG 1308

  Fly  1280 KTSVLAALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPRHGFYDS 1344
            |:|:...:.|:.....|||.:|.:|:..:.|..||.||.:|.|:|.||.|::|.||||.:.:.|.
Zfish  1309 KSSLALGIFRILEAAKGEIYIDGINIAEIGLHDLRSRITIIPQDPVLFSGSLRMNLDPFNAYSDE 1373

  Fly  1345 EIWHAIKNSAAATLLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDD 1409
            |:|:|::.:.....:.:....|:.:....|.|||.|||||:|||||||:..||:.:||.|:.||.
Zfish  1374 EVWNALELAHLKNFVSELPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKVLVLDEATAALDL 1438

  Fly  1410 ESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIFY 1470
            |:|..||..:|:.|:.|.:|.|||||..:....::||:|.|.:.|..:|.:|.:.....:|
Zfish  1439 ETDTLIQSTIRSQFEDCAVLTIAHRLNTIMDYTKVIVMDKGHVVEMDSPSNLIAKRGQFYY 1499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	458/1621 (28%)
		ABC_membrane	328..560	CDD:294371	62/236 (26%)
		ABCC_MRP_domain1	621..827	CDD:213217	85/208 (41%)
		ABC_membrane	948..1192	CDD:279056	71/243 (29%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	91/219 (42%)
abcc6a	XP_009300481.1	MRP_assoc_pro	5..1506	CDD:188098	458/1621 (28%)
		ABC_membrane	317..584	CDD:279056	70/266 (26%)
		ABCC_MRP_domain1	630..831	CDD:213217	88/231 (38%)
		ABC_membrane	955..1218	CDD:279056	77/284 (27%)
		ABCC_MRP_domain2	1267..1487	CDD:213211	91/219 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	1	1.000	-	-		FOG0000087
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100026
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.720