Protein Alignment CG7806 and Mrp5

DIOPT Version :10

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_001262747.1
• Gene: Mrp5 / 42362
• FlyBaseID: FBgn0038740
• Length: 1408
• Species: Drosophila melanogaster
• Alignment Length: 1352
• Identity: 410/1352 - (30%)
• Similarity: 641/1352 - (47%)
• Gaps: 159/1352 - (11%)

  Fly   227 QDEANLGSRFLFHWVQPLILKGVAGKLRKIEDLFDLPDALNITR---LSEKLHLA---------- 278
            ::::|:.|..:|.:..|...||    .:|..|..||..||...|   |..||..|
  Fly    14 REKSNIFSSLMFCFAMPTFFKG----RKKTLDENDLYRALQEHRSDHLGSKLSAAWEKEVEKKRK 74

  Fly   279 LSQSQSLWRALHRCFGVEFYLIGILRLIADLSGF--AGPLLLGGLL-------RQDHADPNQVYY 334
            ..::.||.:|....||.....:|::..|.:: ||  ..||.||||:       .|:..:..:.|.
  Fly    75 KKKTPSLLKASMNVFGWRLAGLGLVLFILEI-GFRVTQPLFLGGLVAYYADASNQEGDNQTKAYL 138

  Fly   335 YALGLFGSTLLSAVCATHF--DWRMAM--VSMKMRVGVVNSIYRKALE----ARGLKESKPDLLN 391
            ||||:    :|::.|...|  .:.:.|  :.||.|:.:.:.||||||.    |.| ..:...::|
  Fly   139 YALGV----ILTSACNVLFMHPYMLGMFHIGMKARIAMTSMIYRKALRLSRTALG-DTTIGQVVN 198

  Fly   392 LMSTDTDRIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPINRWLAKRIGIF 456
            |:|.|..|:..|.|..::.|..|.::....||:|.::|.:...||....|.||:..:|.|:..:.
  Fly   199 LISNDVGRLDVSVIHMNYLWLGPVEIGIITYLMYREIGISAFFGVAVMLLFIPLQAYLGKKTSVL 263

  Fly   457 SSGLMTAKDARLSATTETMQGAKQIKINAWEDIFITKIRGLRQEELRFLSKRKYLDAMC---VYF 518
            ........|.|:....|.:.|.:.||:.|||..|...|..:|.:|:..:....|:....   :.|
  Fly   264 RLKTALRTDERVRMMNEIISGIQVIKMYAWEIPFSKMINYVRTKEMNAIRNVNYIRGTLQSFIMF 328

  Fly   519 WATTPVLMCLLTFGVSVLMGNPLIASTTYTSVALLYMLIGPLNA-FPWVLNGLIEAWVSIKRVQQ 582
            .....|.:.|:.|   ||:|..|.|...:...|...:|...:.. ||..::...|..|||:|:|.
  Fly   329 VTRISVFVSLVGF---VLLGKLLTAEKAFVITAYYNILRNTMTVYFPMGISQFAELLVSIRRIQT 390

  Fly   583 LM---DVPNLDYSSYYNPIMRGSGGSGAGDDAPLDAPKASVLQMKCASFCHDSDEQTSP------ 638
            .|   :....|.|...:....|..|..|   .|..|....||:        .|..:||.
  Fly   391 FMLHEETKVRDKSEDLDEQKLGKAGLIA---EPTVAQTTGVLK--------PSSRRTSEAEHSIV 444

  Fly   639 ------------TPFRMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCVQELTT 691
                        |...:.:|::..|..|||.:.||||.||||.:.|::..|....|.|   ::..
  Fly   445 ISKLKAKWDQKNTDNTLDNISLKFKPRQLVAVIGPVGSGKSSLIQAVLGELNPDSGSV---KVNG 506

  Fly   692 GFGYVPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQILG-GDLVGVGENGRTLSGG 755
            ...|..|.|||..||:|.||::|...|:..|:||:..||||.|.::|. .|...|||.|.:||||
  Fly   507 TLSYASQEPWLFTGTVRQNILFGLPMDKHRYRTVVKRCALERDFELLPYADKTIVGERGASLSGG 571

  Fly   756 QRARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCILRLLKHKTRIVVTRNIQLFFHANQI 820
            |:||::||||||:...:|||||.||::|.||.||:...|:...|:.:..::||..:|....|:.|
  Fly   572 QKARISLARAVYRKADIYLLDDPLSAVDTHVGRHLFDQCMRGFLREEIVLLVTHQLQFLEQADVI 636

  Fly   821 LQVKDGQLLPS---EYMTQS----IELSLDEDADDE-------------QEPTVRRRSVELSNQY 865
            :.:..|::...   |.|.:|    .::..|....||             |...:|.|...:|:.
  Fly   637 VIMDKGKISAMGTYESMAKSGLDFAQMLTDPSKKDEGAGDAPDKKSLSRQNSKLRDRHGSISSM- 700

  Fly   866 DKKSLDSLLLE------ELREYGHLSGNVFTCYWKAVTSPLAFTVLLSVVLMQLTRNLSDAWLAY 924
             :.:.:||..|      |.|..|.:...::..|:.|....|........:..|:..:..|.:|:|
  Fly   701 -ESAAESLAAESPMQTQEGRVEGRIGMKLYKKYFGANGYGLFIVFAFFCIGAQVLASGGDIFLSY 764

  Fly   925 WVTETTLDPHKN-DTSLDHILMR-----PTVGNETESGHTTKFYLSIFTAIAVSNSLVTLARAFL 983
            ||       :|| :...|..:.|     |......::.....:|   ||.|.||..:.:|.|:.|
  Fly   765 WV-------NKNGEAERDTFMARLRRAFPETRINADTDPVDIYY---FTGINVSVIIFSLVRSML 819

  Fly   984 FAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNRFSSDTNTVDDSLPF----ILNILLAQ 1044
            |.|..::::..:|..:.:.|..|..:||:....||||||||.|...||:.||.    ::.|.||
  Fly   820 FFYLAMRSSTTLHNTMFQGVTRAAMHFFNTNPSGRILNRFSKDLGQVDEILPSVMMDVMQIFLA- 883

  Fly  1045 LAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHASRDIKRLSSNAMSPLYTHFTETLQGL 1109
            :.|:|..||:   ...|..|..:.:|.::..|:..|...|||:|||.:...||:|:|.:.:|.||
  Fly   884 IVGIVVVLCI---INVWYILATVFLVIVFYLLRVFYLSTSRDVKRLEAVTRSPIYSHLSASLNGL 945

  Fly  1110 TTIRSMRASPRFQRDFQVKLEESIKAQ----LTQSAAQQWLALRLQLLGTLLVGGAGLLAAITAS 1170
            .|||:..|......:|....:......    .|..|...||.....:          .:|.||.|
  Fly   946 ATIRAFGAQKELIAEFDNYQDMHSSGYYMFLATSRAFGYWLDCVCVV----------YIAVITLS 1000

  Fly  1171 ----HTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERIDQYLQLEEEQN--ASGSAE 1229
                ...|.|.|||.|:.|:.:||.:...:...||.|..:.||||:.:|..||.|.:  :..:.:
  Fly  1001 FFLFSPENGGDVGLAITQAMGMTGMVQWGMRQSAELENTMTAVERVVEYEDLEPEGDFESKPNKK 1065

  Fly  1230 PPFGWPTQGVLSFREVQLSYREHLAP--ALRGITFQTEAFERIGIVGRTGAGKTSVLAALLRVAP 1292
            ||..||..|.:.|.::.|.|....|.  .||.:....|..|::||||||||||:|::.||.|::
  Fly  1066 PPKDWPEDGKIVFDDLSLKYFPDKAADYVLRSLNIAIEGCEKVGIVGRTGAGKSSLINALFRLS- 1129

  Fly  1293 LTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPRHGFYDSEIWHAIKNSAAAT 1357
            ...|.|.:|:.:...|.|..||.:|.:|.|||.||.||:|.||||...:.|:::|.:::......
  Fly  1130 YNEGAILIDRRDTNDLGLHDLRSKISIIPQEPVLFSGTMRYNLDPFDEYSDAKLWESLEEVKLKQ 1194

  Fly  1358 LLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDDESDLSIQQALRNA 1422
            ::.....||..|:...|.|.|.|||||:|||||:|:..:::.:||.|:|:|.::|..||..:||.
  Fly  1195 VVADLPSGLQSKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQTTIRNK 1259

  Fly  1423 FKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNP-QSLASDSSTIFYGML 1473
            ||.||:|.|||||..:...|:::|:|.|:..|.|:| :.|.:....:|:.|:
  Fly  1260 FKDCTVLTIAHRLHTVMDSDKVLVMDAGKAVEFGSPFELLTTSEKKVFHSMV 1311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	409/1349 (30%)
Mrp5	NP_001262747.1	MRP_assoc_pro	79..1315	CDD:188098	393/1283 (31%)