Protein Alignment CG7806 and abcc4

DIOPT Version :9

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_001007039.2
• Gene: abcc4 / 368620
• ZFINID: ZDB-GENE-030616-511
• Length: 1331
• Species: Danio rerio
• Alignment Length: 1323
• Identity: 425/1323 - (32%)
• Similarity: 683/1323 - (51%)
• Gaps: 136/1323 - (10%)

  Fly   230 ANLGSRFLFHWVQPLILKGVAGKLRKIEDLFDLPDALNITRLSEKLHLALSQSQSLW-------- 286
            |||.|:..|.|:.||...|...:|.: :|:|::.......:|.|:|       ||.|
Zfish    20 ANLFSQIFFCWLNPLFSIGSKRRLEE-DDMFNVLPEDRSKKLGEEL-------QSYWDQEKEKAA 76

  Fly   287 ---------RALHRCFGVEFYLIGILRLIADLSGFAGPLLLGGLLR-------QDHADPNQVYYY 335
                     :|:.||:...:.::|:..||.:......|:.||.|::       .|.|..::.|.|
Zfish    77 KELKTPKLTKAIIRCYWKSYAVLGVFTLIEESIKVIQPVFLGKLIKYFENYRHDDMAALSEAYGY 141

  Fly   336 ALGLFGSTLLSAVCATHFDWRMAMVSMKMRVGVVNSIYRKAL----EARGLKESKPDLLNLMSTD 396
            |.|:..|||..|:....:.:.:....||:|:.:.:.||||||    .|.| :.:...::||:|.|
Zfish   142 ATGVCLSTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYRKALCLSAAAMG-QTTTGQIVNLLSND 205

  Fly   397 TDRIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPINRWLAKRIGIFSSGLM 461
            .::.....|..||.|..|.:....:.||:.::|.:.|||:.....|:|:.....|....:.|...
Zfish   206 VNKFDELTIFLHFLWVGPLQAAAVIGLLWQEIGPSCLAGMAVLVFLMPLQTMFGKLFSKYRSKTA 270

  Fly   462 TAKDARLSATTETMQGAKQIKINAWEDIFITKIRGLRQEELRFLSKRKYLDAMCVYFWATTPVLM 526
            ...|:|:....|.:.|.:.||:.|||..|...:..:|::|:..:....||..:.:..:.|...::
Zfish   271 ALTDSRIRTMNEVVSGIRIIKMYAWEKPFAMLVNDVRRKEISKIMSSSYLRGLNMASFFTANKII 335

  Fly   527 CLLTFGVSVLMGNPLIAS------TTYTSVALLYMLIGPLNAFPWVLNGLIEAWVSIKRVQQLMD 585
            ..:||.|.||:||.:.||      :.|::|.|...|.     ||..:..:.|:.:||:|:::.:.
Zfish   336 LFVTFTVYVLVGNTMSASRVFVAVSLYSAVRLTVTLF-----FPAAIEKVSESAISIRRIKKFLL 395

  Fly   586 VPNLDYSSYYNPIMRGSGGSGAGDDAPL--DAPKASVLQMKCASFCHDSDEQTSPTPFRMKDINV 648
            :..|                 ..:..||  :..|...::|: ...|:......:||   ::::..
Zfish   396 LDEL-----------------VKNHLPLSQEEKKEPSVEMQ-DLICYWDKTLDAPT---LQNVCF 439

  Fly   649 DIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCVQ-ELTTGFGYVPQSPWLQRGTIRDNIV 712
            .:|.|||:.:.||||.||||.||.::..|....|.:.|: |||    |..|.||:..||||.||:
Zfish   440 TVKPGQLLAVIGPVGAGKSSLLSTVLGELPAEKGVIKVKGELT----YASQQPWVFPGTIRSNIL 500

  Fly   713 WGAQFDEQWYKTVLHACALEEDLQIL-GGDLVGVGENGRTLSGGQRARVALARAVYQDKKVYLLD 776
            :|.:...|.|:.||.||||:.|:::| .|||..:|:.|.||||||:|||.||||||||..:||||
Zfish   501 FGKELQPQRYERVLRACALKRDMELLPDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLD 565

  Fly   777 DVLSSLDAHVARHIIKHCILRLLKHKTRIVVTRNIQLFFHANQILQVKDGQLLP----SEYMTQS 837
            |.||::||.|:||:.:.|:..:||.|.||:||..:|....|||||.:|:|.::.    ||.....
Zfish   566 DPLSAVDAEVSRHLFEQCVCGILKDKPRILVTHQLQYLKAANQILVLKEGHMVARGSYSELQQSG 630

  Fly   838 IELSLDEDADDEQEP--------------TVRRRSVE------LSNQYDKKSLDS----LLLEEL 878
            ::.:.....|:|:|.              ||.:.||.      ||.:.|...|.:    .:.|||
Zfish   631 LDFTSLLKKDEEEESGSEKGEAPRSPRSRTVSQNSVRSHSSSVLSVKDDSDQLPAEPVHTMAEEL 695

  Fly   879 REYGHLSGNVFTCYWKAVTSPLAFTVLLSV-VLMQLTRNLSDAWLAYWVTE-TTLDPHKNDTSLD 941
            |..|::...::..|::|..:.:...:||.: :|.|....|.|.||:||.|| ..||.:.|:|:.
Zfish   696 RSEGNIGIRMYWKYFRAGANVVMLVLLLLLNLLAQTFYILQDWWLSYWATEQEKLDHNTNNTNT- 759

  Fly   942 HILMRPTVGNETESGHTTK-----FYLSIFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLK 1001
                     |.|.:|:||:     |||.|:..:..:..:....|..:...|.:.:|..:|.::..
Zfish   760 ---------NNTSAGNTTQQLDLNFYLGIYAGLTGATIVFGFMRCLIMFNALVSSAEMLHNRMFN 815

  Fly  1002 KVMFAKFNFFDITSVGRILNRFSSDTNTVDDSLPFILNILLAQLAGLVGALCVSLYAMPWLGLVI 1066
            .::.....||||..:||||||||.|...:|..||:.....:.....:||.:.|:...:||:.:.:
Zfish   816 SILRTPVRFFDINPIGRILNRFSKDIGHLDSLLPWTFVDFIQVFLQIVGVIAVASSVIPWILIPV 880

  Fly  1067 IPMVPIYLSLQQRYRHASRDIKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEE 1131
            :|::..:|.|::.:...|||:||:.|...||:::|.:.:||||.|||:.:|..|||:.|....:.
Zfish   881 LPLLICFLFLRRYFLRTSRDVKRIESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDL 945

  Fly  1132 SIKAQLTQSAAQQWLALRLQLLGTLLVGGAGLLAAITA------SHTTNPGLVGLCISYALSITG 1190
            ..:|........:|.|:||.       |...:...|||      ..|.|.|.|||.:|||:::.|
Zfish   946 HSEAWFLFLTTSRWFAVRLD-------GMCSVFVTITAFGCLLLKDTMNAGDVGLALSYAVTLMG 1003

  Fly  1191 QLGDLLHAVAETEQELVAVERIDQYLQLEEEQNASGSAEPPFGWPTQGVLSFREVQLSYREHLAP 1255
            .....:...||.|..:.:|||:.:|.:||.|........|...||.:|:::|..|..||......
Zfish  1004 MFQWGVRQSAEVENMMTSVERVVEYTELESEAPWETQKRPSPDWPNRGLITFDRVNFSYSSDGPV 1068

  Fly  1256 ALRGITFQTEAFERIGIVGRTGAGKTSVLAALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVI 1320
            .|:.|:......|::||||||||||:|:::||.|::. ..|:|.:|.|....:.|..||:::.:|
Zfish  1069 VLKNISAMFRPREKVGIVGRTGAGKSSLISALFRLSE-PEGKILVDGVLTSEIGLHDLRQKMSII 1132

  Fly  1321 TQEPFLFEGTVRENLDPRHGFYDSEIWHAIKNSAAATLLVQQLGGLDGKVETCGNNLSAGQRQLL 1385
            .|:|.||.||:|:||||.:...|.::|.|::.......:.:..|.|:.::...|:|.|.|||||:
Zfish  1133 PQDPVLFTGTMRKNLDPFNQHSDHDLWKALEEVQLKAAVEELPGKLETELAESGSNFSVGQRQLV 1197

  Fly  1386 CLARALLKNAKVVAIDEGTSNLDDESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDG 1450
            |||||:|:..:|:.|||.|:|:|..:|..||:.:|:.||.||:|.|||||..:...|||:|||.|
Zfish  1198 CLARAILRKNRVLIIDEATANVDPRTDELIQKTIRDKFKECTVLTIAHRLNTIIDSDRILVLDAG 1262

  Fly  1451 RICEEGNPQSLASDSSTIFYGML 1473
            ||.|...|..|..:.|.|||.|:
Zfish  1263 RIHEYDAPHVLLQNQSGIFYKMV 1285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	424/1320 (32%)
		ABC_membrane	328..560	CDD:294371	66/241 (27%)
		ABCC_MRP_domain1	621..827	CDD:213217	94/207 (45%)
		ABC_membrane	948..1192	CDD:279056	77/254 (30%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	91/219 (42%)
abcc4	NP_001007039.2	SunT	11..1289	CDD:331423	425/1323 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100026
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.720