Protein Alignment CG7806 and MRP

DIOPT Version :9

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_723772.2
• Gene: MRP / 34686
• FlyBaseID: FBgn0032456
• Length: 1549
• Species: Drosophila melanogaster
• Alignment Length: 1635
• Identity: 480/1635 - (29%)
• Similarity: 756/1635 - (46%)
• Gaps: 254/1635 - (15%)

  Fly     2 SSVVD--WGDFAWNWTQFCPTGLKPFANETNDLLPCFQEILLQLPVYTLFAAISAYNF----GNQ 60
            ||.:|  .|...||.|:..      :.|:. |..|||::..|.......:.|...::|    .:.
  Fly     6 SSPMDRFCGSTFWNATETW------YTNDP-DFTPCFEQTALVWTPCAFYWAFVIFDFYYLKASL 63

  Fly    61 SRHVVRNGLQLRMLSIRTFLAMVLAL-LPVAKVFAFHQQGVELFAADL---LVVSAECIMWVVHS 121
            .|::..|.|.:....:...|.::.|| |.:|.|.......:.|:..|:   ::..|..::..:
  Fly    64 DRNIPWNKLNVSKALVNLGLLVITALDLIMALVKKGGDSELPLYDLDVWGPIIKFATFLLLFI-- 126

  Fly   122 GFLLTARQYGELSHRGSLLINVVWLTVVVLDAVWLRT------------------SRHFSWWPWS 168
             |:...|:|| :...|...|  .|..:.||.....||                  .:.|||..:.
  Fly   127 -FIPLNRKYG-VQTTGCQFI--FWFLLTVLSIPRCRTEVRLDAERQKILNSQQPSEQDFSWEEYQ 187

  Fly   169 LATLVCDLLF-GVTLIPKGSAVYSSLPRSGVSAREDEGLLSQRYTYFQFDLNESHLGHAQDEANL 232
            ..:......| .:.||....|  ..:||.               |.:|...||.    .:..|:.
  Fly   188 FVSFFIFFTFTSIMLILNCFA--DGMPRQ---------------TKYQRGENEI----PELSASF 231

  Fly   233 GSRFLFHWVQPLILKGVAGKLRKIEDLFDL----------------------PDALNITRLSEKL 275
            .||..:.|...:.|||....|.: :||:||                      .:..|..|:..|.
  Fly   232 LSRITYQWFDKMALKGYRNPLEE-KDLWDLRPQDSCSEVMPIFAHHWNQNVRKNYKNKARVEPKA 295

  Fly   276 HLALSQ----------------SQSLWRALHRCFGVEFYLIGILRLIADLSGFAGP----LLLGG 320
            ..:...                ..|:...:::.||..|....:::|..|...||.|    |::..
  Fly   296 QFSNGNVTFENPHGEKNGRKKGMASIMPPIYKSFGGVFLFGALMKLFTDTLTFAQPQVLSLIISF 360

  Fly   321 LLRQDHADPN-QVYYYALGLFGSTLLSAVCATHFDWRMAMVSMKMRVGVVNSIYRKALEARG--L 382
            :..|| |:|. :...||:.||............:..||.:|.:::|..::|:||||||....  .
  Fly   361 VEAQD-AEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYRKALRISNSTK 424

  Fly   383 KESK-PDLLNLMSTDTDRIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPIN 446
            |||. .:::|||:.|..|.:......:..||.|.::...||.|:.|||.:.|||:....:|||:|
  Fly   425 KESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVN 489

  Fly   447 RWLAKRIGIFSSGLMTAKDARLSATTETMQGAKQIKINAWEDIFITKIRGLRQEELRFLSKRKYL 511
            ..:|.||..:....|..||.|:....|.:.|.|.:|:.|||..|..::..:|.:|:..|....||
  Fly   490 GVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIATLRSTAYL 554

  Fly   512 DAMCVYFWATTPVLMCLLTFGVSVLM--GNPLIASTTYTSVALLYMLIGPLNAFPWVLNGLIEAW 574
            :|...:.|:..|.|:.|:||...||.  .|.|.......|:||..::..||...|.:...:.|..
  Fly   555 NAGTSFLWSCAPFLVSLVTFATYVLTSEANQLSVEKVLVSIALFDLMKLPLTILPMLSVDIAETQ 619

  Fly   575 VSIKRVQQLMDVPNLDYSSYYNPIMRGSGGSGAGDDAPLDAPKASVLQMKCASFCHDSDEQTSPT 639
            ||:.|:.:.::...||.:|..:                 |:.|...:.::...|.. .||.|
  Fly   620 VSVNRINKFLNSEELDPNSVLH-----------------DSSKPHPMSIENGEFSW-GDEIT--- 663

  Fly   640 PFRMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCVQELTTG-FGYVPQSPWLQ 703
               :::||:::|.|.||.:.|.||.||||.:.|.:..::...|.|    .|.| ..||||..|:|
  Fly   664 ---LRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVV----NTVGKLAYVPQQAWIQ 721

  Fly   704 RGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQIL-GGDLVGVGENGRTLSGGQRARVALARAVY 767
            ..|:||||::|..:|.:.|..|:.||||..|:.|| .|||..:||.|..|||||:.|::||||||
  Fly   722 NATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVY 786

  Fly   768 QDKKVYLLDDVLSSLDAHVARHIIKHCI--LRLLKHKTRIVVTRNIQLFFHANQILQVKDGQLLP 830
            .|..:|||||.||::||||.:||.:..|  ..:|..|:|::||..:......:.|..:|.|::..
  Fly   787 SDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISE 851

  Fly   831 SEYMTQSIE----------LSLDEDADDEQE------------------PTVRR-----RSVELS 862
            |....|.::          ..|.|..::|:|                  .||.:     |:..||
  Fly   852 SGTFDQLVKNKGAFADFIIQHLQEGNEEEEELNQIKRQISSTADVPELLGTVEKAIKLARTESLS 916

  Fly   863 NQYDKKSLDSL-----------------------------------LLE-ELREYGHLSGNVFTC 891
            :.....|.|||                                   |:| |..:.|.:...|:..
  Fly   917 DSISVTSADSLMGGGGSLRRRTKRQDSHDSVASAASLKKKQEVEGKLIETEKSQTGGVEFAVYKH 981

  Fly   892 YWKAVTSPLAFTVLLSVVLMQLTRNLSDAWLAYWVTETTLDPHKNDTSLDHILMRPTVGNETESG 956
            |.|:|...|:...|:...:.|..:..|:.||..|..:..:   .|||.|
  Fly   982 YIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWANDQNV---ANDTGL---------------- 1027

  Fly   957 HTTKFYLSIFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKF-NFFDITSVGRIL 1020
              ...||.::.|......::......:....|.:||..:|.:||..::.... .|||||.:||:|
  Fly  1028 --RDMYLGVYGAFGFGQGVLAYFAVVIVYLGGFQAAKTIHNELLAVIIRGSVCRFFDITPIGRLL 1090

  Fly  1021 NRFSSDTNTVDDSLPFILNILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHASR 1085
            |.||.|.:.||:.||..::..:..:..::..:.|...:.|....||:|:..:|...|:.|...||
  Fly  1091 NSFSGDMDVVDEELPATMDSFMTFIFMVLATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSR 1155

  Fly  1086 DIKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAAQQWLALRL 1150
            .:.||.|.:.||:|:||:||:.|.:|||:.....||..:...|::::...:.....|.:|||:||
  Fly  1156 QLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANRWLAIRL 1220

  Fly  1151 QLLGTLLVGGAGLLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERIDQY 1215
            :::|.|::..|.|.|.:...  ||||||||.:||||.:|..|..|:...::.|..:|:||||.:|
  Fly  1221 EMVGNLIILFASLFAVLGGQ--TNPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEY 1283

  Fly  1216 --------LQLEEEQNASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERIGI 1272
                    .:||:::|      .|..||.:|.:.|:..|:.|||.|...|||::|..:..|::||
  Fly  1284 GETKQEAPWELEQDKN------KPKNWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGI 1342

  Fly  1273 VGRTGAGKTSVLAALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDP 1337
            ||||||||:|:..||.|:.....|.|.:|.|::.::.|.:||.|:.:|.|:|.||.|::|.||||
  Fly  1343 VGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDP 1407

  Fly  1338 RHGFYDSEIWHAIKNSAAATLLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDE 1402
            .....|.|||.|::.|...:.:.....||:.::...|.|||.|||||:|||||||:..||:.:||
  Fly  1408 FEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDE 1472

  Fly  1403 GTSNLDDESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSST 1467
            .|:.:|.|:|..||:.:|..||.||:|.|||||..:...|::||||.|:|.|..:|..|..:..:
  Fly  1473 ATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKS 1537

  Fly  1468 IFYGMLLAQD 1477
            .||.|  |:|
  Fly  1538 AFYSM--AKD 1545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	475/1624 (29%)
		ABC_membrane	328..560	CDD:294371	74/237 (31%)
		ABCC_MRP_domain1	621..827	CDD:213217	84/209 (40%)
		ABC_membrane	948..1192	CDD:279056	76/244 (31%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	98/219 (45%)
MRP	NP_723772.2	MRP_assoc_pro	14..1548	CDD:188098	477/1627 (29%)
		ABC_membrane	338..601	CDD:279056	83/263 (32%)
		ABCC_MRP_domain1	649..848	CDD:213217	84/209 (40%)
		ABC_membrane	988..1260	CDD:279056	87/294 (30%)
		ABCC_MRP_domain2	1308..1528	CDD:213211	98/219 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I246
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	1	1.000	-	-		FOG0000087
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100026
Panther	1	1.100	-	-	P	PTHR24223
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.870