Protein Alignment CG7806 and abc3

DIOPT Version :9

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_595055.1
• Gene: abc3 / 2540937
• PomBaseID: SPBC359.05
• Length: 1465
• Species: Schizosaccharomyces pombe
• Alignment Length: 1567
• Identity: 462/1567 - (29%)
• Similarity: 742/1567 - (47%)
• Gaps: 251/1567 - (16%)

  Fly    39 ILLQLPVYTLFAAISA---YNFGNQSRHVVRNGLQLRMLSIRTFLAMVLALLPVAKVFAFHQQ-- 98
            ::|.:|  .|||.:|.   |.|..:.|....:..|...:.::.|   .:||:.:.:::..::.
pombe    10 LVLLIP--NLFALVSGGLQYVFDVRRRIFRPHFSQFWTIWMKFF---SIALVIITQIYVGYKTKN 69

  Fly    99 -GVELFAADLLVVSAECIMWVVHSGFLLTARQYGELSHRGSLLINVVWLTVVVLDAVWLRTSRHF 162
             |...|:     |...|.:.     ||..|.|........||||  .||..||...:.|..|.:.
pombe    70 IGWNFFS-----VVTYCFVL-----FLQFAEQSTLRVPMASLLI--FWLLKVVTSLLILLFSPYI 122

  Fly   163 SWWPW----SLATLVCDLLFGVT--LIPKGSAVYSSLPRSGVSAREDEGLLSQRYTYFQFDLNES 221
            :....    :|.||.|.|:..::  .:|..:.|:.|...:.|   |::|:......|
pombe   123 AITSMARLLTLITLFCSLVCFISEVYVPPCNRVWYSDDTNEV---EEKGIRPSEVRY-------- 176

  Fly   222 HLGHAQDEANLGSRFLFHWVQPLILKGVAGKLRKIEDLFDLPDALNITRLSEKLHLALS------ 280
                    ||:.|:..|.|:...|..|....|:: .|::.||.    ...|..|.:...
pombe   177 --------ANIFSKLSFSWISSFIKFGYTNYLKE-SDVWLLPP----DERSGNLIIGFEDWWIYH 228

  Fly   281 -----QSQSLWRALHRCFGVEFY-------LIGILRLIADLSGFAGP-------LLLGGLLRQDH 326
                 :|..||:.|       |:       ||.|.:||.|:..|..|       |.:......:.
pombe   229 SKNKRRSLFLWKLL-------FFNHWKLVALITITKLIQDVLAFVQPTLIQKTILFISSYTSPNP 286

  Fly   327 ADPNQVYYYALGLFGSTLLSAVCATHFDWRMAMVSMKMRVGVVNSIYRKAL----EARGLKESKP 387
            ..|::.:..|:.:..:..|..:....::..:.::.|:.:..::.|||||:|    .|| ...|..
pombe   287 ESPSRGFIIAILVLVANFLQTLLLQQYNQLIMLLGMRWKTELLASIYRKSLLLSSSAR-QNRSIG 350

  Fly   388 DLLNLMSTDTDRIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPINRWLAKR 452
            |::|.|:.||.:|.:..|......|.||::...|..||..:|.:...||..:.:|.|.|..:|..
pombe   351 DIINYMAVDTQKISDLPIYLFIIVSGPFQIALALSNLYHLMGYSAFTGVAASVILFPCNIIVANV 415

  Fly   453 IGIFSSGLMTAKDARLSATTETMQGAKQIKINAWEDIFITKIRGLRQ-EELRFLSKRKYLDAMCV 516
            ...|.|.||..||:|....||.:...:.||:.|||..|:.|:..:|. :||..|.|..::.|:..
pombe   416 YKKFQSILMKNKDSRSKLMTEIINNIRSIKLYAWETPFLQKLLHIRNTKELSMLKKIGFITAIGD 480

  Fly   517 YFWATTPVLMCLLTFGVSVLM---GNPLIASTTYTSVALLYMLIGPLNAFPWVLNGLIEAWVSIK 578
            :.|..|.:::..:.||..::.   ...|.|...:.:|:|..:|..||...|.|::.|:||.||:.
pombe   481 FAWIFTTIIVTTVAFGAFIIFHGKTQALTADIVFPAVSLFNLLQFPLAMLPTVISSLLEASVSVS 545

  Fly   579 RVQQLMDVPNLDYSSYYNPIMRGSGGSGAGDDAPLDAPKASVLQMKCASFCHDS---DEQTSPTP 640
            |:.:.:....||    ||.:.|...         .:.|....|::|..:|....   .:|.:||
pombe   546 RIYEFLIAQELD----YNGVQRFPA---------TEIPHEICLEIKSGTFSWSKKTLKQQVTPT- 596

  Fly   641 FRMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEV--CVQELTTGFGYVPQSPWLQ 703
              ::.||...|.|:|.||.|.||.||||.|.|.:.|:....|.|  |     ....|..|.||:.
pombe   597 --LRQINFVAKNGELTCIFGKVGAGKSSLLEACMGNMYKNSGSVFQC-----GSLAYAAQQPWIF 654

  Fly   704 RGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQIL-GGDLVGVGENGRTLSGGQRARVALARAVY 767
            ..|||:||::|::||.:.|:..:|||.|:.|.:|. .||...||:.|.:|||||::|::||||:|
pombe   655 DATIRENILFGSEFDPELYEKTIHACCLKRDFEIFTEGDQTEVGQKGASLSGGQKSRISLARAIY 719

  Fly   768 QDKKVYLLDDVLSSLDAHVARHIIK-----------HCI------LRLLKHKTRIVVTRN----- 810
            ....:|||||||||:|.||:|.:||           ||:      |.:||....|.:..|
pombe   720 SQADIYLLDDVLSSVDQHVSRDLIKNLFGPEGFLRTHCVVLTTNSLNVLKEADSIYILSNGKIVE 784

  Fly   811 ----IQLFFHANQILQ--------VKDGQLLPSEYMTQ--SIELSLDEDADDEQEPTVRRRSVEL 861
                ..||...|..|:        .||.|.|| |:.|.  |.::||        .|::....:|.
pombe   785 KGNYEHLFVSTNSELKQQLSEFNDEKDTQPLP-EHTTSYPSTQISL--------APSIHVEGLET 840

  Fly   862 ---------SNQY--------------DKKSLDSLLLEELREYGHLSGNVFTCYWKAVTSPLA-- 901
                     ||:|              |.|.......:||.:.|.:..:|:..|:|:.:..|.
pombe   841 YSSSERKDSSNKYKSRKRNPIRQKVTEDDKGKCVAQTDELVQRGKVKWHVYWMYFKSCSIGLILL 905

  Fly   902 -FTVLLSVVLMQLTRNLSDAWLAYWVTETTLDPHKNDTSLDHILMRPTVGNETESGHTTKFYLSI 965
             |..::|.::|.:..|:   ||.:|..|       |..|            .:|...:..|||.|
pombe   906 YFFFIISGIMMNVATNV---WLKHWSEE-------NGKS------------SSELNPSPYFYLGI 948

  Fly   966 F------TAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNRFS 1024
            :      :...:|:|.:|:.     ...||::..::|:.:||.::.|...||:.||.||||||||
pombe   949 YLFFGFLSCAFISSSSLTMT-----VLCGIRSGRYLHDSMLKTILRAPMGFFETTSSGRILNRFS 1008

  Fly  1025 SDTNTVDD--SLPFIL---NILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHAS 1084
            :|...||:  ||.|:.   |.:  |:..::|.:|   |:.|...|:|:|:..:||..:..|...|
pombe  1009 NDVYKVDEVVSLTFMFFFRNSI--QVLFILGVIC---YSAPLSLLLIVPLFFLYLYNRAYYVRTS 1068

  Fly  1085 RDIKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAAQQWLALR 1149
            |::|||.:...||||.|..|:|.||:|||:......|..:..::::.:.:......::.:|.|:|
pombe  1069 RELKRLDNVTRSPLYAHVQESLSGLSTIRAYGMQETFVEENDLRIDTNHRVWFMFFSSSRWQAIR 1133

  Fly  1150 LQLLGTLLV---GGAGLLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVER 1211
            ::.:|.|::   ...|:|:||..|  .||||||..:|||:.||..|..::....:.|...|:|||
pombe  1134 VECIGDLIIFCTAFYGILSAIKGS--PNPGLVGFSLSYAIQITQGLSFIVQQSVDAENNTVSVER 1196

  Fly  1212 IDQYLQLEEE------QNASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERI 1270
            |.:|:.::.|      :|     .||..|||.|.:||......|||.|:.||..|..:....|:|
pombe  1197 ILEYINVKSEAPEIIPEN-----RPPCEWPTDGAVSFNHYSAKYREDLSFALNNINIEISPREKI 1256

  Fly  1271 GIVGRTGAGKTSVLAALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENL 1335
            ||||||||||:::..||.|:...|.|:|.:|..::....|..||.|:.:|.||..:|||.:||||
pombe  1257 GIVGRTGAGKSTLAMALFRIIEPTEGKIEIDNEDITKFGLYDLRSRLSIIPQESQIFEGNIRENL 1321

  Fly  1336 DPRHGFYDSEIWHAIKNSAAATLLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAI 1400
            ||.|...|.:||..::.::....:.|...||..:|...|.|.|:|||||:||||.||.:.:::.:
pombe  1322 DPNHRLTDKKIWEVLEIASLKNCISQLEDGLYSRVAEGGANFSSGQRQLICLARVLLTSTRILLL 1386

  Fly  1401 DEGTSNLDDESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDS 1465
            ||.|:::..|:|..:||.:|..||..|:|.:|||:..:...|||:|||.|::.|....:.|..:.
pombe  1387 DEATASVHAETDAIVQQTIRKRFKDRTILTVAHRINTVMDSDRILVLDHGKVVEFDATKKLLENK 1451

  Fly  1466 STIFYGM 1472
            .::||.:
pombe  1452 DSMFYSL 1458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	462/1565 (30%)
		ABC_membrane	328..560	CDD:294371	64/239 (27%)
		ABCC_MRP_domain1	621..827	CDD:213217	89/245 (36%)
		ABC_membrane	948..1192	CDD:279056	83/257 (32%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	90/219 (41%)
abc3	NP_595055.1	MRP_assoc_pro	101..1464	CDD:188098	440/1461 (30%)
		ABC_membrane	254..527	CDD:294371	71/273 (26%)
		ABCC_MRP_domain1	575..781	CDD:213217	83/213 (39%)
		ABC_membrane	907..1177	CDD:279056	93/303 (31%)
		ABCC_MRP_domain2	1224..1443	CDD:213211	90/218 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000087
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100026
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.710