Protein Alignment CG7806 and Abcc12

DIOPT Version :10

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_766500.3
• Gene: Abcc12 / 244562
• MGIID: 2441679
• Length: 1366
• Species: Mus musculus
• Alignment Length: 1358
• Identity: 357/1358 - (26%)
• Similarity: 646/1358 - (47%)
• Gaps: 147/1358 - (10%)

  Fly   228 DEANLGSRFLFHWVQPLILKGVAGKLRKIEDL-----FDLPDALNITRL----SEKLHLALSQSQ 283
            |:|.|.|...|.|:.|::::.....| .::.|     :|..| :|..|.    .|::.....:..
Mouse    47 DDAGLLSFATFSWLTPVMIRSYKHTL-TVDTLPPLSPYDSSD-INAKRFQILWEEEIKRVGPEKA 109

  Fly   284 SLWRALHRCFGVEFYLIGILRLIADLSGFAGPLLLGGLLRQDHADPNQVYYYALGLFGSTLLSAV 348
            ||.|.:.:.......:..:..::..:....||.:|...:.| |.......:..:|:   .|..|:
Mouse   110 SLGRVVWKFQRTRVLMDVVANILCIVMAALGPTVLIHQILQ-HITSISSGHIGIGI---CLCLAL 170

  Fly   349 CATHFD----WRMA-----MVSMKMRVGVVNSIYRKALEARGLKE-SKPDLLNLMSTDTDRIVNS 403
            ..|.|.    |.:|     ..:::::|.:...|:...|..:.|.. |..::||::|:|:..:..:
Mouse   171 FTTEFTKVLFWALAWAINYRTAIRLKVALSTLIFENLLSFKTLTHISAGEVLNILSSDSYSLFEA 235

  Fly   404 CISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPINRWLAKRIGIFSSGLMTAKDARL 468
            .:......:||..:.......:..||:..|.|:....:.|||..::||....|....::..|.|:
Mouse   236 ALFCPLPATIPILMVVCAVYAFFILGSTALVGISVYLIFIPIQMFMAKLNSTFRRSAISVTDKRV 300

  Fly   469 SATTETMQGAKQIKINAWEDIFITKIRGLRQEELRFLSKRKYLDAMCVYFWATTPVLMCLLTFGV 533
            ....|.:...|.||:.|||:.||..|..:|:.|.:.|.|..|:.:...........:..:.||..
Mouse   301 QTMNEFLTCIKLIKMYAWEESFINTIHDIRKREKKLLEKAGYVQSGNSALAPIVSTIAIVSTFTC 365

  Fly   534 SVLMGNPLIASTTYTSVALLYMLIGPLNAFPWVLNGLIEAWVSIKRVQQLMDVPNLDYSSYYNP- 597
            .:.:...|.|...::.:|:..::...:...|:.:..:.||.||::|::::: :.....|....|
Mouse   366 HIFLKRKLTAPVAFSVIAMFNVMKFSIAILPFSVKAVAEASVSLRRMKKIL-IAKSPPSYITQPE 429

  Fly   598 ------------------IMRGSGGSGAGDDAPLDAPKASVLQM--------KCASFCHDSDE-- 634
                              |.|.|           |.|||.:.:.        :..|....||:
Mouse   430 DPDTILLLANATLTWEQEINRKS-----------DPPKAQIQKRHVFKKQRPELYSEQSRSDQGV 483

  Fly   635 -----QTSPTPFRMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCVQELTTGFG 694
                 |:......:.:|:..::.|:::.|.|.||.||||.:||::..:|...|.|.|   .....
Mouse   484 ASPEWQSGSPKSVLHNISFVVRKGKVLGICGNVGSGKSSLISALLGQMQLQKGVVAV---NGPLA 545

  Fly   695 YVPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQILG-GDLVGVGENGRTLSGGQRA 758
            ||.|..|:..|.:|:||::|.:::.|.|:..:|.|.|::||..|. |||..:||.|..||||||.
Mouse   546 YVSQQAWIFHGNVRENILFGEKYNHQRYQHTVHVCGLQKDLNSLPYGDLTEIGERGVNLSGGQRQ 610

  Fly   759 RVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCILRLLKHKTRIVVTRNIQLFFHANQILQV 823
            |::||||||.::::|||||.||::||||.:|:.:.||.:.||.||.::||..:|.....::::.:
Mouse   611 RISLARAVYANRQLYLLDDPLSAVDAHVGKHVFEECIKKTLKGKTVVLVTHQLQFLESCDEVILL 675

  Fly   824 KDGQL---------------------------------LPSEYMTQSIELS---LDEDA------ 846
            :||::                                 :.:..|.::::.|   .||||
Mouse   676 EDGEICEKGTHKELMEERGRYAKLIHNLRGLQFKDPEHIYNVAMVETLKESPAQRDEDAVLASGD 740

  Fly   847 --DDEQEPTVRRRSVELSNQYDKKS-LDSLLLEELREYGHLSGNVFTCYWKAVTSPL-AFTVLLS 907
              |:.:||       |.....|..: ...|:..|..:.|.::...:..|.||....| :|.||..
Mouse   741 EKDEGKEP-------ETEEFVDTNAPAHQLIQTESPQEGIVTWKTYHTYIKASGGYLVSFLVLCL 798

  Fly   908 VVLMQLTRNLSDAWLAYWV---TETTLDPHKNDTSLDHILMRPTVGNETESGHTTK--FYLSIFT 967
            ..||..:...|..||..|:   ::.......|.|:.          |..::...||  .|..::.
Mouse   799 FFLMMGSSAFSTWWLGIWLDRGSQVVCASQNNKTAC----------NVDQTLQDTKHHMYQLVYI 853

  Fly   968 AIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNRFSSDTNTVDD 1032
            |..||..:..:.:.|.|....:.|:..:|.::..|::.:..:|||.|..||::||||.|.:.:|.
Mouse   854 ASMVSVLMFGIIKGFTFTNTTLMASSSLHNRVFNKIVRSPMSFFDTTPTGRLMNRFSKDMDELDV 918

  Fly  1033 SLPFILNILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHASRDIKRLSSNAMSP 1097
            .|||.....|.|...:|..|.:.....|.:.:|:..:..|:|.|.:.:....:::|::.:.:.||
Mouse   919 RLPFHAENFLQQFFMVVFILVIMAAVFPVVLVVLAGLAVIFLILLRIFHRGVQELKQVENISRSP 983

  Fly  1098 LYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAAQQWLALRLQLLGTLLVGGAG 1162
            .::|.|.::|||..|.:..........|:...:|:....|..:.|.:|.|||:.:|..::.....
Mouse   984 WFSHITSSIQGLGVIHAYDKKDDCISKFKTLNDENSSHLLYFNCALRWFALRMDILMNIVTFVVA 1048

  Fly  1163 LLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERIDQYLQ--LEEEQNAS 1225
            ||..::.| :.:....||.:||.:.::|.|...:....||:.:..:.|.:.:|:.  :.|..:..
Mouse  1049 LLVTLSFS-SISASSKGLSLSYIIQLSGLLQVCVRTGTETQAKFTSAELLREYILTCVPEHTHPF 1112

  Fly  1226 GSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERIGIVGRTGAGKTSVLAALLRV 1290
            .....|..||::|.::|::.::.||::....|.|:....::.:.:|||||||:||:|:..||.|:
Mouse  1113 KVGTCPKDWPSRGEITFKDYRMRYRDNTPLVLDGLNLNIQSGQTVGIVGRTGSGKSSLGMALFRL 1177

  Fly  1291 APLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPRHGFYDSEIWHAIKNSAA 1355
            .....|.|.:|:|::.|:.|..||.::.:|.|:|.||.||||.||||.....|..:||.::.:..
Mouse  1178 VEPASGTIIIDEVDICTVGLEDLRTKLTMIPQDPVLFVGTVRYNLDPLGSHTDEMLWHVLERTFM 1242

  Fly  1356 ATLLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDDESDLSIQQALR 1420
            ...:::....|..:|...|.|.|.|:|||||:|||||:|:|::.:||.|:::|.::|..:|..::
Mouse  1243 RDTIMKLPEKLQAEVTENGENFSVGERQLLCMARALLRNSKIILLDEATASMDSKTDTLVQSTIK 1307

  Fly  1421 NAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIFYGMLLAQDI 1478
            .||||||:|.|||||..:...|.::|:::|::.|...|:.||....:.| .||||.::
Mouse  1308 EAFKSCTVLTIAHRLNTVLNCDLVLVMENGKVIEFDKPEVLAEKPDSAF-AMLLAAEV 1364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	353/1350 (26%)
Abcc12	NP_766500.3	MRP_assoc_pro	43..1366	CDD:188098	357/1358 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	470..492		4/21 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	726..749		8/29 (28%)