Protein Alignment CG7806 and mrp-3

DIOPT Version :9

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_001359552.1
• Gene: mrp-3 / 181677
• WormBaseID: WBGene00003409
• Length: 1505
• Species: Caenorhabditis elegans
• Alignment Length: 1554
• Identity: 434/1554 - (27%)
• Similarity: 710/1554 - (45%)
• Gaps: 264/1554 - (16%)

  Fly    73 MLSIRTFLAMVLALLPVAKVFAF----------HQQGVELFAADLLVVSAECIMWVVHSGFLLTA 127
            ::|::.|:|   :||.:.::|.|          |:.    ..|||.::.      ..||..||
 Worm    54 LMSLKWFVA---SLLIIDRLFVFLLAVWESLFEHKN----VTADLFIIP------FFHSFTLL-- 103

  Fly   128 RQYGELSHRGSLLI--NVVWLTVVVLDAVWLRTSRHFSWWPWSLATLVCD-LLFGVTLIPKGSAV 189
                      :|||  |.|           .|...|      |...|.|. :||.|..:|:....
 Worm   104 ----------ALLIATNEV-----------RRAGIH------SSGPLFCIWMLFAVAAVPEFYQW 141

  Fly   190 YSSLPRSGVSAREDEGLLSQRYTYFQFDLNE----------------SHLGHAQDEANLGSRFLF 238
            .::..:..:.||.|........|||...:.|                .:|...::.||..||.|.
 Worm   142 MTTGSQPELVARIDFFRYVAYLTYFPLVVAEFVLHFVSDPFPMPRGYQNLKCPEENANFISRQLL 206

  Fly   239 HWVQPLILKGVAGKLRKIEDLFDLPDALN----------------------ITRLSEKLHLALSQ 281
            .|...:|..|....| ..:|:|::...::                      ..:|.:|...|.:.
 Worm   207 LWFTQIISLGYERTL-VADDVFEMDSQMDQEYLKARWKTEWLKQTEKAREKQVKLDDKRERARTG 270

  Fly   282 SQ------------------------------SLWRALHRCFGVEFYLIG--ILRLIADLSGFAG 314
            |:                              :||:.:      ::.::|  .::.::||..||.
 Worm   271 SEKAPLLGTFNNYGAVNLDDKDRVIVQPSVIVTLWQIM------KWEILGGSFIKFLSDLLQFAN 329

  Fly   315 PLLLGGLLRQDHADPNQVYY----YALGLFGSTLLSAVCATHFDWRMAMVSMKMRVGVVNSIYRK 375
            |..|..|:..... ||....    .|:|||.:..:.::....:...|..|..|::..:..::|.|
 Worm   330 PTFLNYLILFIET-PNAPLINGIGLAVGLFLAGQIKSLFMNTYFIAMTRVGAKIQTMLSCAVYEK 393

  Fly   376 AL----EARGLKESKPDLLNLMSTDTDRIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGV 436
            :|    .|| .:.:..:::|::|.|.||..........:||.||::...:.||...:|.|..||:
 Worm   394 SLLLSNTAR-RERTVGEMVNILSIDVDRFRMITPQIQQYWSSPFQIIICMVLLSQTIGVAVWAGI 457

  Fly   437 IFAALLIPIN--------RWLAKRIGIFSSGLMTAKDARLSATTETMQGAKQIKINAWEDIFITK 493
            :....::|||        ||..:        ||..||.|:....|.:.|.|.:|::|||......
 Worm   458 VVMISIVPINICVSMITKRWQLR--------LMKYKDERIRLINEVLNGIKVVKLSAWETAMEET 514

  Fly   494 IRGLRQEELRFLSKRKYLDAMCVYFWATTPVLMCLLTFGVSVLMG--NPLIASTTYTSVALLYML 556
            |..:|.:||:.:.:...|...........||.:.|.:|.|.||:.  |.|..:..:.|::|..:|
 Worm   515 IERVRDKELKMIKQSALLKTFADCLNVGAPVFVALSSFTVFVLIDPKNVLTPNIAFVSLSLFNLL 579

  Fly   557 IGPLNAFPWVLNGLIEAWVSIKRVQQLMDVPNLDYSSYYNPIMRGSGGSGAGDDAPLDAPKASVL 621
            .|||.....::...::..||.|||:..:....:|.::....| ||.             ...:.:
 Worm   580 RGPLMMAAELVAQTVQLVVSNKRVRTFLCEKEVDTAAIDKEI-RGE-------------LYTNTV 630

  Fly   622 QMKCASFCHDSDEQTSPTPFRMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCV 686
            ::...||..||.|...     :.||.....:.:||.:.|.||.||||.|.|.:..::...|.|.|
 Worm   631 EIHSGSFAWDSAEARI-----LSDIEFLAGSKELVTVVGSVGSGKSSLLLAALGEMEKVCGYVGV 690

  Fly   687 QELTTGFGYVPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDL-QILGGDLVGVGENGR 750
            :   ....|:.|.||:...:::.|::..|..::..||.|:.:|||:||| |:..||...:||.|.
 Worm   691 R---GSVAYLSQQPWILNQSLKKNVLMQADLNDVLYKKVIESCALKEDLKQLPDGDDTEIGEKGI 752

  Fly   751 TLSGGQRARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCI--LRLLKHKTRIVVTRNIQL 813
            .|||||:||:||||||||.|.||.|||.||::||||.:||..:.|  ..:|.|.|||:||.....
 Worm   753 NLSGGQKARIALARAVYQSKDVYFLDDPLSAVDAHVGKHIFDNVIGPNGMLSHTTRILVTNCTSF 817

  Fly   814 FFHANQILQVKDGQL---------------------LPSEYMTQSIELSLDEDADDEQEPTV--- 854
            ...:.:|:.:|||::                     :.:|| .|:.|.|.:|...:|....:
 Worm   818 LQESGKIIVMKDGRIKHCGTYNELLTDVEAREYLQEVDNEY-AQAQESSGEESGGEENSDILPGS 881

  Fly   855 -----------------RRRSVELSNQYDKKSLDSLLLEELREYGHLSGNVFTCYWKAV-----T 897
                             |::|  .|:..:||..|:|:.:|....|.::..|:..|:||:     .
 Worm   882 IASGSRMSRLSRLSKISRKKS--KSSIVEKKKPDALITKEEAAIGRVNPGVYLLYFKAMGIVTYV 944

  Fly   898 SPLAFTVLLSVVLMQLTRNLSDAWLAYWVTETTLDPHKNDTSLDHILMRPTVGNETESGHTTKFY 962
            .|.|..|:|: |...|.|:|   ||..| ::..:|.:..||.        :||..
 Worm   945 LPYAIAVVLN-VSFALGRSL---WLTAW-SDANIDINHPDTM--------SVGAR---------- 986

  Fly   963 LSIFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNRFSSDT 1027
            |.::....::..:.......|....|:.|:..:|:.||..|:....::||||.:|||:||.:.|.
 Worm   987 LGVYAGFGITEVIFLFFSLVLLLIGGVAASKNLHKPLLHNVLRNPLSYFDITPIGRIINRLAKDM 1051

  Fly  1028 NTVDDSLPFILNILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHASRDIKRLSS 1092
            ..||..|......|:..|..:|..:.:..|..|....:|||:..||..:.:....::|.::|::|
 Worm  1052 EVVDLRLSSSFRFLVMALINMVQTVLIVSYTTPLFIAIIIPVFIIYFFVLKYSIKSTRQLQRIAS 1116

  Fly  1093 NAMSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAAQQWLALRLQLLGTLL 1157
            ...||::::|:|||||::|:|:.:.|..|.|.....|...:|.......|.:||::||:|||.::
 Worm  1117 LTRSPIFSNFSETLQGISTVRAFQWSDEFVRRNDEHLNTHVKCSYYSQMANRWLSIRLELLGNIV 1181

  Fly  1158 VGGAGLLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERIDQYLQLEEEQ 1222
            :..|.:||.|........|::||.:||:|:||..|...:..:.|.|..:|:|||||:|.:.:.|.
 Worm  1182 IFSAAILAIIGKESGITAGMLGLSVSYSLNITFMLNMFVRQINEVETNVVSVERIDEYSKTKSEA 1246

  Fly  1223 N-ASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERIGIVGRTGAGKTSVLAA 1286
            . ...:...|..|||.|.::..:....||:.|...|:.|:......:::|:.|||||||:|:..|
 Worm  1247 EWRLDNNNLPSNWPTGGAVNIEDYSCRYRDELDLVLKQISLNILPGQKVGVCGRTGAGKSSLALA 1311

  Fly  1287 LLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPRHGFYDSEIWHAIK 1351
            |.|:.....|.|.:||.....:.|..|||::.:|.||..||..|:|.|:||:..|.|.::|.|::
 Worm  1312 LFRIVEAADGNISIDQTITSHIGLHDLREKLTIIPQENVLFANTLRFNIDPKGQFTDQQLWLALE 1376

  Fly  1352 NS---AAATLLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDDESDL 1413
            ||   |...||..:   |:..|...|.|.|.||||||||.||||:.:||:.:||.|:.:|:.:|.
 Worm  1377 NSNLKAHVELLPHK---LESPVAEGGENFSVGQRQLLCLTRALLRKSKVLVLDEATAGIDNRTDT 1438

  Fly  1414 SIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIFYGM 1472
            .:|..:|..|...|::.|||||..:...|||||:|.|||.|:|.|..|..:.::.|||:
 Worm  1439 MVQATIREKFADSTIITIAHRLHTIIDYDRIIVMDAGRIVEDGIPGELLKNRNSQFYGL 1497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	433/1552 (28%)
		ABC_membrane	328..560	CDD:294371	64/249 (26%)
		ABCC_MRP_domain1	621..827	CDD:213217	82/208 (39%)
		ABC_membrane	948..1192	CDD:279056	71/243 (29%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	89/222 (40%)
mrp-3	NP_001359552.1	MRP_assoc_pro	25..1501	CDD:188098	434/1554 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53842
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	1	1.000	-	-		FOG0000087
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100026
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.730