Protein Alignment CG7806 and mrp-5

DIOPT Version :9

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_510479.1
• Gene: mrp-5 / 181587
• WormBaseID: WBGene00003411
• Length: 1427
• Species: Caenorhabditis elegans
• Alignment Length: 1410
• Identity: 409/1410 - (29%)
• Similarity: 670/1410 - (47%)
• Gaps: 191/1410 - (13%)

  Fly   180 VTLIPKGSAVYSSLPRS-----------GVSAREDEG--------LLSQRYTYFQFDLNESHLGH 225
            |.|...|:.||.::..|           |.:.|:..|        |:..|.|    :.|:::.|.
 Worm     8 VCLQQSGTGVYENVVYSKETSDRAKRYAGDTNRKTIGRYSAAVQNLIPLRTT----ERNKNNGGS 68

  Fly   226 AQDEANLGSRFLFHWVQPLILKGVAGKLRKIE----DLFDLPDALNITRLS---EKLHLALSQSQ 283
            ..|:|.|.|...:.||.|.:.:.|.|||.:.:    ..:| ...||:.||.   |....|.::|.
 Worm    69 RIDDAGLFSFVTYSWVFPYLYQAVRGKLDRNQVWGCSFYD-SCGLNMARLEVLWEDEKKANAKSP 132

  Fly   284 SLWRALHRCFGVEFYLIGILRLIADLSGFAGPL-----LLGGLLRQDHADPNQVYYYALGLFGST 343
            ||::.::|......:....:.....:.||.||.     |:......:..:.:::.|    .:|..
 Worm   133 SLFKVIYRFISTRLWFSCAVFFFCLIFGFIGPTCFIRRLIAFAENPERDEQSRIVY----SYGIA 193

  Fly   344 LLSAVCATHF--------DWRMA-MVSMKMRVGVVNSIYRKALEARGL-KESKPDLLNLMSTDTD 398
            |::|:....|        .|.:: ...:::|..|:..:|:..|.::.| .:::.|::|:.:.|..
 Worm   194 LVAAISVVEFARVLSYGATWAVSYRTGIRVRGAVLALLYKNVLNSKDLCGKTESDVINIFANDGQ 258

  Fly   399 RIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPINRWLAKRIGIF------S 457
            |:.::.            .|..|.|    :|...|.|.| ..||:.|.||....|.:|      .
 Worm   259 RLFDAV------------TFAPLVL----VGPLVLVGGI-GYLLMVIGRWSLLGILVFFVFDVIQ 306

  Fly   458 SGL-----------MTAKDARLSATTETMQGAKQIKINAWEDIFITKIRGLRQEELRFLSKRKYL 511
            .||           :...:.|:|...|.::..:.:|:|.||.||..||...|:||...:.|..|.
 Worm   307 FGLGKSMVACRNLAIVKTEKRISMMAEIIKYIRIVKMNGWEQIFSAKIDQFRKEEKVQIRKSGYA 371

  Fly   512 DAMCVYFWATTPVLMCLLTFGVSVLMGNPLIASTTYTSVALLYMLIGPLNAFPWVLNGLIEAWVS 576
            .::.:......||:..:|||...||.||.|:||..::::.:.::::..:...|:....|.||.|:
 Worm   372 QSLAIACGPVVPVVAAILTFVGVVLAGNDLLASDAFSAITVYFVMLFGIRMIPYGSRYLAEAVVA 436

  Fly   577 IKRVQQLMDVPNLDYSSYYNPIMRGSGGSGAGDDAPLDAPKAS-VLQMKCASFCHDSDEQTSPTP 640
            ::|:|:.:.:.  .|:.|  |:..       .:|..||...|: ..|.|.|.  ...||...||.
 Worm   437 MRRIQEYLLLE--QYAPY--PVTN-------AEDVVLDCQGATYTYQPKAAK--APVDETKEPTE 488

  Fly   641 ----------FRMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCVQELTTGFGY 695
                      |......:.||.|:.:.:.|.||.|||:.|.||..::..||..:.|....|  .|
 Worm   489 NEVIVVETPVFTCSFDKLSIKRGEHIAVIGAVGCGKSAILKAISGHMFTTDDALSVDRSQT--VY 551

  Fly   696 VPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQILG-GDLVGVGENGRTLSGGQRAR 759
            |||..|:..||::|||::|.:.:.:.|...::.|.|.|||..|. ||...|||.|.||||||:||
 Worm   552 VPQKAWIFNGTVQDNILFGDKMNSERYYKAVNGCQLTEDLTTLSVGDRTEVGERGATLSGGQKAR 616

  Fly   760 VALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCILRLLKHKTRIVVTRNIQLFFHANQILQVK 824
            |||||||:|.|.:||.||:.:|||..||..|.:..|.:|||.|..::||.|::|..|.:::|.|:
 Worm   617 VALARAVFQTKNLYLFDDIFASLDKKVANKIHEEIIQKLLKKKALMMVTNNMELLHHFDRVLFVE 681

  Fly   825 DGQLLP-----------SEYMT--------QSIELSLDEDADDEQEPT------VRRRSVELSNQ 864
            .|.::.           ..|.|        |:...:.....|...:|.      :|..|.:|...
 Worm   682 GGNIVADGNHDILYEKNDAYKTFVDACETYQATSGATSPCGDGPAQPAPLDAEILRNSSEDLKGD 746

  Fly   865 YDKKSLDSLLLEEL----------REYGHLSGN--VFTCYWKAVTSPLAFTVLLSVVLMQLTRNL 917
            .||...|.   |::          ::|.|.:|.  ::||        |....:::||
 Worm   747 ADKLISDE---EDMGNSTIAWRIYKQYIHAAGGWPIWTC--------LVIGFIVNVV-------- 792

  Fly   918 SDAWLAYWVTETTLDPHKNDTSLDHILMRPTVGNETE---------SGHTTKFYLSIFTAIAVSN 973
            |:.:..||::......|...|         |:.|.||         ....|.||.:::....|..
 Worm   793 SNIFSTYWLSRWLKKGHDETT---------TITNGTEFLEMKTSLADSPVTGFYAAVYLVALVVL 848

  Fly   974 SLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNRFSSDTNTVDDSLPFIL 1038
            ::..|.:|.:|....:.||..:|:::.:.|:....:|||.|..||||||||.|.:.:|..|||..
 Worm   849 TISGLFKACVFVKVSLTAATRLHDRMFQAVIHGATSFFDSTPTGRILNRFSKDMDEIDVKLPFTA 913

  Fly  1039 NILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHASRDIKRLSSNAMSPLYTHFT 1103
            .:.|..:...:|.|.|.....|:..|..||:..:::.....:|...|::||....:.||||.|.:
 Worm   914 EVFLQNMITCLGFLVVITSVFPYFLLFAIPLFVVFVVFVSCFRAGIRNLKRSEHISRSPLYDHVS 978

  Fly  1104 ETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAAQQWLALRLQLLGTLLVGGAGLLAAIT 1168
            .:|:|:|||.:.:.|.||....:..|:.:..|.....:|.:|||:.|.||..::.....|| .:.
 Worm   979 ASLEGITTIHTFQQSNRFLEVLKKHLDCNSGAIFMFQSAMRWLAVWLDLLVVVMTAIVALL-TVM 1042

  Fly  1169 ASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERIDQY---LQLEEEQNASGSAEP 1230
            .:.|.:|...|:.|::|:.::|.....:....|.|.::.:|||:..|   :..:.|.|.....:.
 Worm  1043 LTGTVSPADAGMAIAFAVQMSGIFQFAVRTQTELEAKMTSVERVSYYADNIPEDGEWNTRQGLDI 1107

  Fly  1231 PFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERIGIVGRTGAGKTSVLAALLRVAPLTH 1295
            ...||..|.::|.||.|.||:....||..|||:.:..|::||:||||:||:|:...:.|:.|:|:
 Worm  1108 ESSWPANGQINFSEVNLRYRKSHPLALNDITFEIKGGEKVGIIGRTGSGKSSLANLIFRLYPVTN 1172

  Fly  1296 GEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPRHGFYDSEIWHAIKNSAAATLLV 1360
            |.|.:|.|:::|:.|..||..|..|.|:|.||.||||.||||...:.||.||.|::.....| ||
 Worm  1173 GTIYIDGVDIRTVGLVKLRRGISAIAQDPSLFSGTVRFNLDPSLEYSDSMIWEALEKCHLKT-LV 1236

  Fly  1361 QQLG-GLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDDESDLSIQQALRNAFK 1424
            |.|. .|:..|...|||.|.|:|||.|||||||..:::|.:||.|:::|..:|..||:.::..|.
 Worm  1237 QSLDKKLEADVSHGGNNFSVGERQLFCLARALLMKSRIVILDEATASVDAGTDKLIQEVIKTVFA 1301

  Fly  1425 SCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIF 1469
            ..|::.|||||..:..||||:.|.:|::.....||.:..|..:::
 Worm  1302 DATVIIIAHRLDNVRNMDRIMHLKNGKLINFTTPQEMFKDDWSVY 1346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	409/1410 (29%)
		ABC_membrane	328..560	CDD:294371	59/258 (23%)
		ABCC_MRP_domain1	621..827	CDD:213217	87/216 (40%)
		ABC_membrane	948..1192	CDD:279056	74/252 (29%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	95/220 (43%)
mrp-5	NP_510479.1	MRP_assoc_pro	90..1340	CDD:188098	387/1316 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100026
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820