Protein Alignment CG7806 and pgp-14

DIOPT Version :9

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_510128.1
• Gene: pgp-14 / 181416
• WormBaseID: WBGene00004008
• Length: 1327
• Species: Caenorhabditis elegans
• Alignment Length: 1416
• Identity: 300/1416 - (21%)
• Similarity: 564/1416 - (39%)
• Gaps: 333/1416 - (23%)

  Fly   256 IEDLFDLPDALNITRLSEKLHLALSQSQ--------------SLWRALHRCFGVEF-YLIGILRL 305
            ::|..|.|.....:.|.:.|:.||.:..              .|:|     :|.:| ||:..:..
 Worm    50 VDDDDDAPKMYTPSLLEKILNYALCRGDIANQQLEAQPVSIPGLFR-----YGKKFDYLLLFIGT 109

  Fly   306 I-ADLSGFAGPL--LLGGLLR-------------QDHADPNQVYYYALGLFGS--TLLSAVCATH 352
            | |.:||.:.|:  |:.|.:.             ::.|:.|...:..:|:|.|  ..:..:|..|
 Worm   110 ICAIISGVSQPILALVSGRVTNALLVYPPTSKQFRNKANENVYIFLGIGIFISITNFIQYMCFQH 174

  Fly   353 FDWRMAMVSMKMRV-----------------GVVNSIYRKALEARGLKESKPDLLNLMSTDTDRI 400
            ...|: |..|:.|.                 |.:.:....::|.  ::|...|.|.::......:
 Worm   175 CCTRV-MAQMRHRFVYSVLRQNAGWFDKNHSGTITTKLNDSMER--IREGIGDKLGVLLRGFAML 236

  Fly   401 VNS-CISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPINRWLAKR-IGIFSSGLMTA 463
            :.: .:::.:.|.          |..:.||.|....:..:.|...:.....|. ||:..:|
 Worm   237 IAAIVVAYIYEWR----------LASMMLGVAPTCCICMSLLARQMTSTTIKELIGVGKAG---- 287

  Fly   464 KDARLSATTETMQGAKQIK-INAWEDIFITKIRGLRQEELRFLSKRKYLDAMCVYFWA------- 520
                 |...|::.|.:.:: .|..|::.     |..:.||.  ..||:  |:...||:
 Worm   288 -----SIAEESLMGVRTVQAFNGQEEMV-----GRYEAELE--KGRKF--AVWKGFWSGFFGGLF 338

  Fly   521 ---TTPVLMCLLTFGVSVL-MGNPLIASTTYTSVALLYMLIGP--LNAFPWVLNGLIEAWVSIKR 579
               ....|.|.:.:|..:| :|  :|.:.....:.::.||:|.  |......:..|:.|.||...
 Worm   339 FFWLFSFLGCGMLYGAYLLKVG--IITTPGDVFIVVMSMLLGAYFLGLISPHMMVLLNARVSAAS 401

  Fly   580 VQQLMD-VPNLD-YSSYYNPIMRGSGGSGAGDDAPLDAPKASVLQMKCASFCHDSDEQTSPTPFR 642
            :.|.:| ||.:| ||.....:....|.                ::.:...|.:.|.:...    .
 Worm   402 IYQTIDRVPKIDPYSKAGKRLQNVVGR----------------VKFENVHFRYPSRKDAK----I 446

  Fly   643 MKDINVDIKAGQLVCIEGPVGGGKSSFLSAIV------ANLQCTDG----EVCVQELTTGFGYVP 697
            :..:|:.::.|..|.:.|..|.|||:.:..:.      |.....||    |:.::.|....|.|.
 Worm   447 LNGLNLVVEPGTSVALVGHSGCGKSTSVGLLTRLYEPEAGNVTIDGTDVRELNIEWLRNTVGIVQ 511

  Fly   698 QSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQIL-----GGDLVGVGENGRTLSGGQR 757
            |.|.|...||.:|::.|.....:  :|::..|.:......:     |.|.: :|:.|..|||||:
 Worm   512 QEPILFNDTIHNNLLIGNPGSTR--ETMIEVCKMANAHDFIEKMPKGYDTL-IGDGGVQLSGGQK 573

  Fly   758 ARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCILRLLKHKTRIVVTRNIQLFFHANQILQ 822
            .|||:||.:.:|.||.|||:..|:|||. :..|::..:....|.:|.|::...:.....|::|:.
 Worm   574 QRVAIARTLIRDPKVLLLDEATSALDAQ-SESIVQSALNNASKGRTTIMIAHRLSTIREADKIVF 637

  Fly   823 VKDGQL-----------LPSEY--MTQSIELSLDEDADDEQE-------PTVR------------ 855
            .:.|.:           |...|  :.::.:...|.:|.:|.|       .|.|
 Worm   638 FEKGVIVEAGNHEELVRLGGRYFDLVKAQQFKADPEATEEFEEEEIDLDDTSRSSRRSSMTSARS 702

  Fly   856 -----RRSVELSNQY--DKKSLD-------------SLLLEE-------LREYGHLSGNVFTCYW 893
                 ||...|::.:  .|:|..             :::.|:       |..:.:..||....:.
 Worm   703 GSEAFRRGNSLNDSFSGSKRSAQADAENSAFAANEAAIMAEDGQITAGYLDIFKNAKGNYLYMFL 767

  Fly   894 KAVTSPLAFTVLLSVVLMQLTRNLSDAWLAYWVTE-TTLDPHKNDTSLDHILMRPTVGNETESGH 957
            ..|     |.::..:.|..|      |.:..||.| .|..|:..                 ...|
 Worm   768 GTV-----FALIRGLELPAL------ALIFGWVFEGFTFVPYGG-----------------RMMH 804

  Fly   958 TTKFYLSIFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFD--ITSVGRIL 1020
            .....:..|.::.|......||.:.|||......::....:..:.:::...::||  ..:.|:::
 Worm   805 RMAMAVIAFASVGVGVWFSQLASSVLFAVVSENLSMRFRVQSFRNLLYQDASYFDNPAHAPGKLI 869

  Fly  1021 NRFSSDT---NTVDDS----LPFILNILLAQLA---------GLVGALCVSLYAMPWLGLVIIPM 1069
            .|.:||.   ..|.|:    :.:.|..::|.:|         |::|...:.|.|...:||.
 Worm   870 TRLASDAPNIKAVVDARMLQVIYALAAIIANIAIAFIYCWQIGILGTSLILLLAFVMIGLA---- 930

  Fly  1070 VPIYLSLQQRYRHASRDIKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIK 1134
                      |:.:..:::::.::....:   ..|.::.:.||:.:.....|...:|...::..:
 Worm   931 ----------YKISLMNVEQIQNDDAGRI---AIEIIENVKTIQLLTRCELFFDHYQTSSKQQKR 982

  Fly  1135 AQLTQSAAQQWLALRLQLLGTLLVGGAGLLAAITASHTTNPGLVGLCISYALSI----------- 1188
            ::|.:                      |::.||..|.|.:.....:|.:||:.|
 Worm   983 SELKK----------------------GMIEAINYSLTQSFMYFMMCFTYAVGIRIIYQGDKSSD 1025

  Fly  1189 ---TGQLGDLLHAVAETEQELVAVERIDQYL-QLEEEQNASGS------AEPPFG-------WPT 1236
               .|.:..:|.|        |||....||. :..:.:.|:|.      .:|..|       ...
 Worm  1026 DTFKGIIAMMLGA--------VAVMNSAQYFPEFVKAKTAAGMLFNIIYRKPRTGDLMEGDRPEI 1082

  Fly  1237 QGVLSFREVQLSYREH-LAPALRGITFQTEAFERIGIVGRTGAGKTSVLAALLRVAPLTHGEIRL 1300
            :|.:.|..|:.||.:. |.|.::|:.:.....:.:.:||.:|:||::.:..|.|...:|.|.:|:
 Worm  1083 RGNILFENVKFSYPQRPLQPIMKGLQWTALRGQTVALVGPSGSGKSTNIGMLERFYDVTGGALRI 1147

  Fly  1301 DQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPRHGFYD---SEIWHAIKNSAAATLLVQQ 1362
            |..:::.|.|..||.::.::.|||.||.||:|||:  ..|..|   .:|..|::.:.|...|...
 Worm  1148 DGQDIRKLSLFHLRTQMALVGQEPRLFAGTIRENV--CLGLKDVPLEKINQALELANANRFLANL 1210

  Fly  1363 LGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDDESDLSIQQALRNAFKSCT 1427
            ..|:|..|...|..||.||:|.:.:||||:::.|::.:||.||.||.||:.::|:||..|.:..|
 Worm  1211 PAGIDTDVGEKGGQLSGGQKQRIAIARALVRDPKILLLDEATSALDSESERAVQEALDRAREGRT 1275

  Fly  1428 LLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIFYGMLLAQDI 1478
            .:.|||||..:...|.|:.:|.|::.|.||...|...... :|.::..||:
 Worm  1276 CITIAHRLSSIQNSDLIVYIDKGKVQEAGNHTQLMHQKGR-YYKLIKKQDL 1325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	298/1408 (21%)
		ABC_membrane	328..560	CDD:294371	47/266 (18%)
		ABCC_MRP_domain1	621..827	CDD:213217	56/220 (25%)
		ABC_membrane	948..1192	CDD:279056	42/275 (15%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	77/223 (35%)
pgp-14	NP_510128.1	PTZ00265	104..1321	CDD:240339	285/1351 (21%)
		ABC_membrane	109..377	CDD:279056	53/300 (18%)
		ABC_MTABC3_MDL1_MDL2	429..666	CDD:213216	59/244 (24%)
		ABC_membrane	769..1039	CDD:294371	54/344 (16%)
		ABC_MTABC3_MDL1_MDL2	1086..1323	CDD:213216	79/239 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000