Protein Alignment CG7806 and pgp-5

DIOPT Version :9

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_001257116.1
• Gene: pgp-5 / 181276
• WormBaseID: WBGene00003999
• Length: 1252
• Species: Caenorhabditis elegans
• Alignment Length: 1213
• Identity: 271/1213 - (22%)
• Similarity: 487/1213 - (40%)
• Gaps: 278/1213 - (22%)

  Fly   397 TDRIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPINRWLAKRIGIFSSGLM 461
            ||.::.:.::|:..|.:      ..|      |..|..|::.:.||   :.|          |.|
 Worm   180 TDFVIGTILAFYTDWRL------ACY------GTVFSFGIVLSGLL---DSW----------GKM 219

  Fly   462 TAKDARLSATTETMQGAKQIKINA---WEDIFITKIRGLRQEELRFLSK----RKY--------- 510
            ...:.:    .|.:..|..|...|   ::.  ::.:.|.:||..|:..:    .||
 Worm   220 KNNEKQ----NEHISNAGSIAFQALGCYKT--VSSLNGQQQEVERYTEELKNGEKYALNRAFVFS 278

  Fly   511 LDAMCVYFWATTPVLMCLLTFGVSVLMGNPLIASTTYTSVALLYMLIGPLNAFPWVLNG---LIE 572
            |.....||: |..:...:|.||.:::....:.....   |.:||          ::|.|   |.|
 Worm   279 LSRSADYFF-TNALNFVILYFGANMIYEGTIEPGVV---VRILY----------YILFGSYCLGE 329

  Fly   573 AWVSIKRVQQLMDVPNLDYSSYYNPIMRGSGGSGAGDDAPLDAPKASVLQMKCASFCHDSDEQTS 637
            |.:.|.|:...:                           ||..|.|.:|....|:......|:..
 Worm   330 AILHISRLASAI---------------------------PLTVPIADILLDSDATADEFFSEEIK 367

  Fly   638 PT--------------PFR-----MKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGE 683
            .|              |.|     :|:|:.:::.|:.:.:.|..|.|||:.:..::.......|.
 Worm   368 DTFQGIISFKNVLFSYPTRPDVPVLKEISFNVQGGECIALVGASGSGKSTVIQLLLHYYNIDSGR 432

  Fly   684 VC----------VQELTTGFGYVPQSPWLQRGTIRDNIVWGA--QFDEQWYKTVLHACALEEDLQ 736
            :.          :::|....|.|.|.|.|...:|.:||.:|.  ..:::....:.:|.|.:....
 Worm   433 ISIDGNDIYNINIKQLRQAMGVVFQEPVLFNTSIEENIRFGKPDATEQEIIDALKNANAFDFVCN 497

  Fly   737 ILGGDLVGVGENGRTLSGGQRARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCILRLLKH 801
            ...|....|||.|..|||||:.|:|:||.:.::.::.|||:..|:|| :.:..|::..:.:....
 Worm   498 FPDGIKTIVGERGAQLSGGQKQRIAIARTLVRNPRILLLDEATSALD-NESEFIVQEALQKASIG 561

  Fly   802 KTRIVVTRNIQLFFHANQILQVKDGQLLP-------------SEYMTQSIELSLDEDADDEQEPT 853
            :|.|||...:....:||:|:.::.|:::.             ...:.|:..:|.:.:..:|.|..
 Worm   562 RTTIVVAHRLSTIRNANKIIVMEKGEIVEVGDHKQLIAMNGVYNNLVQTQLMSTNYEKMNENEER 626

  Fly   854 VRRRSV-------ELSNQ-------YDKKSLDSLLLEELREYGHLSGNVFTC----YWKAVTSPL 900
            |.|:|.       |:|:|       |.||     |:.|::|.|....|:  |    |.::
 Worm   627 VTRQSSHSDFPSNEISHQKIDQEDDYVKK-----LIAEIKEEGAKKSNI--CEIIKYCRS----- 679

  Fly   901 AFTVLLSVVLMQLTRNLSDAWLAYWVTETTL-----DPHKNDTSLDHILMRPTVGNETESGHTTK 960
            .:.:|...||....:.:      |:...:.|     :.:..|.  |.:|.:            :.
 Worm   680 EYCILFIAVLGSAIQGI------YYPLSSQLMIKSYEAYAFDK--DEMLSK------------SH 724

  Fly   961 FYLSIFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFD--ITSVGRILNRF 1023
            |:......:|.:..:....:.:.|.....|.:|.:.....|.:|.....|:|  ..:..|:.||.
 Worm   725 FWALSILFLAFTRPIFIFFQYYFFGKTAEKLSIKLRSMSFKHLMSLPCAFYDDPCHTATRLSNRL 789

  Fly  1024 SSD----TNTVDDSLPFILNILLAQLAGLVGALCVSLYAMPW-LGLVIIPMVP-IYLS------- 1075
            ::|    |..|||.|..::..|:|.|..::.:...|     | :.|.::...| :||:
 Worm   790 NADSSNVTAAVDDRLGSVIMTLVAILLAVIMSFFYS-----WKMSLQVLMFCPLLYLAGYCNDNF 849

  Fly  1076 LQQRYRHASRDIKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPR---FQRDFQVKLEES-IKAQ 1136
            :.|.....|...::.:..|:        |.|:.:.|:|::....|   .......|:..| .|..
 Worm   850 VDQAVEEDSIAFEKSNRAAI--------EALENVRTVRALNMENRVILLVTSHLQKIRNSYFKRA 906

  Fly  1137 LTQSAAQ------------------QWLALRLQLL--GTLLVGGAGLLAAITASHTTNPGLVGLC 1181
            :.|..|.                  .||.||.::|  .|.||       .:|.|.|.
 Worm   907 VIQGTANGFACSCYFFIYAVSFKFGTWLVLREEILPMDTYLV-------LMTLSMTA-------- 956

  Fly  1182 ISYALSITGQLGD---LLHAVAETEQELVAVERIDQYLQLEEEQNASGSAEPPFGWPTQGVLSFR 1243
             |||.|....|.|   .:|| |.....|.....|..|...:.::|..           .|.:..:
 Worm   957 -SYAGSAVAYLPDHRKAIHA-AGLIFHLFTYPAIMPYDSSQGKRNIK-----------NGEIELK 1008

  Fly  1244 EVQLSYREHL-APALRGITFQTEAFERIGIVGRTGAGKTSVLAALLRVAPLTHGEIRLDQVNLKT 1307
            .|...|.:.. ...|.|::.:..|...:.:||.:|:||:::::.|.|......||:::|:.|:..
 Worm  1009 NVSFEYAQRSDKMILDGVSLKLPAGRTLALVGPSGSGKSTIISLLERFYHAVDGEVKIDEENVVD 1073

  Fly  1308 LPLSVLRERIGVITQEPFLFEGTVREN--LDPRHGFYDSEIWHAIKNSAAATLLVQQLGGLDGKV 1370
            :.|..|||.:.:::|||.||..:::||  ....|.....||..|:|.:.|.:.:.|...|||..|
 Worm  1074 VNLHHLRESVSLVSQEPVLFNCSIKENFLFGISHNASQLEIDQALKVANAFSFVSQFPQGLDTLV 1138

  Fly  1371 ETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDDESDLSIQQALRNAFKSCTLLFIAHRL 1435
            ...|..||.||:|.:.:|||:|:|.||:.:||.||.||.:|:..:|.||..|.:..:.:.:||||
 Worm  1139 GERGAQLSGGQKQRIAIARAILRNPKVLLLDEATSALDSDSEKVVQNALDTASERLSTVVVAHRL 1203

  Fly  1436 RGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIFYGMLLAQDI 1478
            ..:...|.|.||.:|::.|:|..:.|....| |::.::..|.|
 Worm  1204 STVVNADSIAVLKNGKVAEQGTHEELLRKRS-IYWRLVQKQGI 1245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	269/1205 (22%)
		ABC_membrane	328..560	CDD:294371	33/178 (19%)
		ABCC_MRP_domain1	621..827	CDD:213217	55/236 (23%)
		ABC_membrane	948..1192	CDD:279056	55/282 (20%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	74/222 (33%)
pgp-5	NP_001257116.1	PTZ00265	27..1241	CDD:240339	269/1207 (22%)
		ABC_membrane	41..322	CDD:294371	33/186 (18%)
		ABC_MTABC3_MDL1_MDL2	374..611	CDD:213216	53/237 (22%)
		ABC_membrane	688..955	CDD:294371	57/306 (19%)
		ABC_MTABC3_MDL1_MDL2	1005..1243	CDD:213216	76/238 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000