Protein Alignment CG7806 and Abcc1

DIOPT Version :10

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_032602.1
• Gene: Abcc1 / 17250
• MGIID: 102676
• Length: 1528
• Species: Mus musculus
• Alignment Length: 1631
• Identity: 511/1631 - (31%)
• Similarity: 775/1631 - (47%)
• Gaps: 275/1631 - (16%)

  Fly     6 DWGDFAWNWTQFCPTGLKPFANETNDLLPCFQE-ILLQLPVYTLFAAISAYNFGNQSRHVVRNGL 69
            |..|..|:|.....|       ...|...|||. :|..:|.:.|::....| |...||| .|..:
Mouse    10 DGSDPLWDWNVTWHT-------SNPDFTKCFQNTVLTWVPCFYLWSCFPLY-FFYLSRH-DRGYI 65

  Fly    70 QLRMLS-IRTFLAMVLALLPVAKVF-AFHQQGVELFAADLLVVSAECI-MWVVHSGFLLTARQYG 131
            |:..|: .:|.|...|.::..|.:| :|.::...:..|.:|:||...: :.::.:.||:
Mouse    66 QMTHLNKTKTALGFFLWIICWADLFYSFWERSQGVLRAPVLLVSPTLLGITMLLATFLI------ 124

  Fly   132 ELSHRGSLLINVVWLTVVVLDAVWLRTSRHFSWWPWSLATLVCDLLFGVTLIPKGSAVYSSLPRS 196
            :|..|..:..:.:.||                :|   |..|:|.|..      ..|.:.|:|.:
Mouse   125 QLERRKGVQSSGIMLT----------------FW---LVALLCALAI------LRSKIISALKK- 163

  Fly   197 GVSAREDEGLLSQRYTYFQFDLNESHLGHAQD------------------EANLGSRFLFHWVQP 243
              .|..|....|..|.||...|.:..|....|                  .|:..||..|.|:..
Mouse   164 --DAHVDVFRDSTFYLYFTLVLVQLVLSCFSDCSPLFSETVHDRNPCPESSASFLSRITFWWITG 226

  Fly   244 LILKGVAGKLRKIEDLFDL-----------------------------------------PDALN 267
            :::.|....|.. .||:.|                                         |...:
Mouse   227 MMVHGYRQPLES-SDLWSLNKEDTSEEVVPVLVNNWKKECDKSRKQPVRIVYAPPKDPSKPKGSS 290

  Fly   268 ITRLSEKLHLALSQS------QSLWRALHRCFGVEFYLIGILRLIADLSGFAGPLLLGGLLR--Q 324
            ...::|::...:.:|      .||::.|::.||..|.:..:.:.:.||..||||.:|..::.  .
Mouse   291 QLDVNEEVEALIVKSPHKDREPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPKILELIINFVN 355

  Fly   325 DHADPN-QVYYYALGLFGSTLLSAVCATHFDWRMAMVS-MKMRVGVVNSIYRKAL---EARGLKE 384
            |...|: |.|:|...||.|..|..: |.|..:.:..|| |:::..||.::|||||   .|.....
Mouse   356 DREAPDWQGYFYTALLFVSACLQTL-ALHQYFHICFVSGMRIKTAVVGAVYRKALLITNAARKSS 419

  Fly   385 SKPDLLNLMSTDTDRIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPINRWL 449
            :..:::||||.|..|.::.....:..||.|.::...||.|:|.||.:.||||....|::|:|..:
Mouse   420 TVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYFLWLSLGPSVLAGVAVMILMVPLNAVM 484

  Fly   450 AKRIGIFSSGLMTAKDARLSATTETMQGAKQIKINAWEDIFITKIRGLRQEELRFLSKRKYLDAM 514
            |.:...:....|.:||.|:....|.:.|.|.:|:.|||..|..|:..:|||||:.|.|..||.|:
Mouse   485 AMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMSIRQEELKVLKKSAYLAAV 549

  Fly   515 CVYFWATTPVLMCLLTFGVSVLMG--NPLIASTTYTSVALLYMLIGPLNAFPWVLNGLIEAWVSI 577
            ..:.|..||.|:.|.||.|.|.:.  |.|.|...:.|:||..:|..|||..|.|::.:::|.||:
Mouse   550 GTFTWVCTPFLVALSTFAVFVTVDERNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSL 614

  Fly   578 KRVQQLMDVPNLDYSSYYNPIMRGSGGSGAGDDAPLDAPKASVLQMKCASFCHDSDEQTSPTPFR 642
            ||::..:....|:..|    |.|.|..||.|:.          :.:|.|:|.....|     |..
Mouse   615 KRLRIFLSHEELEPDS----IERRSIKSGEGNS----------ITVKNATFTWARGE-----PPT 660

  Fly   643 MKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCVQELTTGFGYVPQSPWLQRGTI 707
            :..|...|..|.||.:.|.||.||||.|||::|.:...:|.|   .|.....||||..|:|..::
Mouse   661 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHV---TLKGSVAYVPQQAWIQNDSL 722

  Fly   708 RDNIVWGAQFDEQWYKTVLHACALEEDLQIL-GGDLVGVGENGRTLSGGQRARVALARAVYQDKK 771
            |:||::|....|.:||.|:.||||..||:|| .||...:||.|..|||||:.||:||||||.:..
Mouse   723 RENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSD 787

  Fly   772 VYLLDDVLSSLDAHVARHIIKHCI--LRLLKHKTRIVVTRNIQLFFHANQILQVKDGQLLPSEYM 834
            :||.||.||::||||.:||.:..:  :.|||:||||:||..|......:.|:.:..|::  || |
Mouse   788 IYLFDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKI--SE-M 849

  Fly   835 TQSIELSLDED----------ADDEQEPTVRRRSVELSNQYDKKSLDSLL--------------- 874
            ....|| ||.|          |:.||:......||..|.:..|...:.:|
Mouse   850 GSYQEL-LDRDGAFAEFLRTYANAEQDLASEDDSVSGSGKESKPVENGMLVTDTVGKHLQRHLSN 913

  Fly   875 --------------LEELREYG-------------HLSGNV-FTCYWKAVTSPLAFTVLLSVVLM 911
                          :.||::.|             ..:|.| .:.||..:.:...|...||:.|.
Mouse   914 SSSHSGDTSQQHSSIAELQKAGAKEETWKLMEADKAQTGQVQLSVYWNYMKAIGLFITFLSIFLF 978

  Fly   912 ---QLTRNLSDAWLAYWVTETTLDPHKNDTSLDHILMRPTVGNETESGHTTKFYLSIFTAIAVSN 973
               .::...|:.||:.|..:                  |.|.|.|::..  .|.||::.|:.:
Mouse   979 LCNHVSALASNYWLSLWTDD------------------PPVVNGTQANR--NFRLSVYGALGI-- 1021

  Fly   974 SLVTLARAFLFAYA------GIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNRFSSDTNTVDD 1032
                |..|.:|.|:      ||.|:..:|..||..|:.:..:||:.|..|.::||||.:.:|||.
Mouse  1022 ----LQGAAIFGYSMAVSIGGIFASRRLHLDLLYNVLRSPMSFFERTPSGNLVNRFSKELDTVDS 1082

  Fly  1033 SLPFILNILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHASRDIKRLSSNAMSP 1097
            .:|.::.:.:..|..::||:.:.|.|.|...::|.|:..:|..:|:.|..:||.:|||.|.:.||
Mouse  1083 MIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSP 1147

  Fly  1098 LYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAAQQWLALRLQLLGTLLVGGAG 1162
            :|:||.|||.|::.||:.....||.....:|::|:.||......|.:|||:||:.:|..:|..|.
Mouse  1148 VYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAA 1212

  Fly  1163 LLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERIDQYLQLEEE-----Q 1222
            |.|.| :.|:.:.|||||.:||:|.||..|..|:...:|.|..:|||||:.:|.:.|:|     |
Mouse  1213 LFAVI-SRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ 1276

  Fly  1223 NASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERIGIVGRTGAGKTSVLAAL 1287
            ..:    ||..||..|.:.||:..|.|||.|...|:.|....|..|::||||||||||:|:...|
Mouse  1277 ETA----PPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGL 1337

  Fly  1288 LRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPRHGFYDSEIWHAIKN 1352
            .|:.....|||.:|.||:..:.|..||.:|.:|.|:|.||.|::|.||||...:.|.|:|.|:
Mouse  1338 FRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMAL-- 1400

  Fly  1353 SAAATLLVQQLGGLDGKVET--------C---GNNLSAGQRQLLCLARALLKNAKVVAIDEGTSN 1406
                     :|..|.|.|..        |   |.|||.|||||:|||||||:..|::.:||.|:.
Mouse  1401 ---------ELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAA 1456

  Fly  1407 LDDESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIFYG 1471
            :|.|:|..||..:|..|:.||:|.|||||..:....|:||||.|.:.|.|.|..|..... |||.
Mouse  1457 VDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELLQQRG-IFYS 1520

  Fly  1472 MLLAQD 1477
            |  |:|
Mouse  1521 M--AKD 1524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	508/1624 (31%)
Abcc1	NP_032602.1	MRP_assoc_pro	7..1527	CDD:188098	511/1631 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	876..895		4/18 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	909..929		0/19 (0%)